Surgical Treatment for Pediatric Mediastinal Neurogenic Tumors

Fraga, Jose Carlos; Aydogdu, Bahattin; Aufieri, Roberto; Silva, Gabriel V.M.; Schopf, Luciano Ferraz; Takamatu, Eliziane E.; Brunetto, Algemir Lunardi; Kiely, Edward M.; Pierro, Agostino

doi:10.1016/j.athoracsur.2010.04.086

Cited by 45 publications

(41 citation statements)

References 17 publications

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“…They were mostly asymptomatic round or oval tumours with varying sizes, the largest occupying the whole chest with a maximum diameter of 21 cm. Surgical resection is the method of choice to achieve a complete cure [14]. Different surgical styles were applied towards benign and malignant tumours.…”

Section: Discussionmentioning

confidence: 99%

CT and MRI findings of thoracic ganglioneuroma

Guan

Zhang²,

Zeng³

et al. 2012

The British Journal of Radiology

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Objective: Thoracic ganglioneuroma is sporadic and rarely reported. Pre-operative misdiagnosis often occurs in clinical practice. To improve diagnostic accuracy and facilitate differential diagnosis, we summarised the CT and MRI findings of thoracic ganglioneuroma. Methods: 22 cases of thoracic ganglioneuroma confirmed by surgery and pathology were retrospectively analysed in terms of CT (16 cases) and MRI data (6 cases). Results: Of 22 lesions, 19 occurred in the posterior mediastinum, 2 in the lateral pleura and 1 in the right chest. The CT value of the plain scans ranged from 20 to 40 HU (mean 29.1 HU) in 16 cases. Punctate calcification was noted in four cases. Patchy fat density shadow was found in one case. Arterial-phase CT found nearly no enhancement (6 cases) or slight enhancement (10 cases) with a CT value of 0-12 HU (mean 5.8 HU). In the delayed phase, enhancement was strengthened progressively, and CT value of 10-20 HU (mean 13.6 HU) was achieved after 120 s. T 1 weighted images showed homogeneous hypointense signals in five cases and hypointense signals mixed with patchy hyperintense signal shadow in one case. T 2 weighted images demonstrated heterogeneous hyperintense signals in all six cases, of which the whorled appearance was noted in one case. Gadolinium-diethylenetriaminepentaacetic acid (Gd-DTPA)-enhanced MRI found mildly heterogeneous enhancement in the arterial phase, and progressive mild enhancement in the delayed phase. Conclusion: Thoracic ganglioneuroma shows hypodensity in plain CT. On CT and MRI, non-enhancement or slight enhancement in artery phase and progressive mild enhancement in delay phase are characteristic manifestations of ganglioneuroma in the thorax.

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Section: Discussionmentioning

confidence: 99%

CT and MRI findings of thoracic ganglioneuroma

Guan

Zhang²,

Zeng³

et al. 2012

The British Journal of Radiology

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“…2 Additionally, the use of thoracoscopy has led to a decreased intraoperative blood loss, [9][10][11] decreased postoperative pain, reduced hospital length of stay (LOS), [9][10][11][12][13] fewer chest tubes required and/or earlier removal, 9,13,14 improved cosmetic result, faster return to normal activity, and reduced pulmonary adhesions. 9,[15][16][17][18] Although there are no randomized controlled trials dealing with thoracoscopic and open lung resection, several case series pertaining to non-oncologic-associated thoracoscopic surgeries have demonstrated data to support some of the proposed advantages of a minimally invasive approach.…”

Section: Advantages Of Using a Thoracoscopic Approachmentioning

confidence: 98%

The Role of Thoracoscopic Surgery in Pediatric Oncology

Malkan

Loh

Fernández-Pineda

et al. 2014

Journal of Laparoendoscopic & Advanced Surgical Techniques

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The application of thoracoscopic surgical techniques to pediatric solid tumors represents an important adjunctive tool for the surgical management of childhood cancer. Nearly four decades has passed since the introduction of minimally invasive chest surgery in children, and although the adoption of minimally invasive surgery in general pediatric surgical practice is better recognized, its role in pediatric oncology is still considered a developing field. As no consensus exists regarding the use of thoracoscopy for pediatric thoracic solid tumors, the purpose of this article is to review the current literature surrounding the use of thoracoscopic interventions in pediatric oncology and examine established indications, procedures, and technologic advances.

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“…However, the development of smaller and more accurate surgical instruments and the improvement of surgical techniques have translated into better results for complex thoracoscopic procedures in infants and children [7]. Even in the absence of prospective or randomized studies with children, the literature so far indicates that video-assisted surgery is highly effective for the removal of mediastinal neurogenic tumors in this age group [7,8,10,16,17]. Videoassisted thoracoscopic surgery is associated with low morbidity and shorter operative time, surgery time, and hospital stay when compared with the conventional surgical techniques [7].…”

Section: Commentmentioning

confidence: 98%

“…In addition, no tumor recurrence was noted after a median follow-up of 16 months (range, 8.9-28.6 months). In addition to the surgical resection with tumor-free margins, the less aggressive biological behavior of these tumors located in the thorax has also contributed to a better prognosis regarding regression and aggressiveness [5,14,17].…”

Section: Commentmentioning

confidence: 98%