Surgical Treatment and Recurrence Rate of Aneurysmal Bone Cysts in Children

Dormans, John P.; Hanna, B Guirguis; Johnston, Douglas R.; Khurana, Jasvir S.

doi:10.1097/01.blo.0000126336.46604.e1

Cited by 145 publications

(128 citation statements)

References 14 publications

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“…The 5% recurrence rate demonstrated in this series, particularly with juxtaphyseal lesions, provides an acceptable comparative recurrence rate [1,11,16,17,25,28,33,35,36,42,44] with which to pursue further study of this percutaneous treatment option. Furthermore, when recurrence (evidence of residual foci of tumor cells) occurs, patients are able to pursue a minimally invasive option of percutaneous treatment of small recurrent foci.…”

Section: Resultsmentioning

confidence: 82%

“…In addition, evidence of new bone healing provides key information for the physicians involved that treatment was progressing in the proper direction. Evidence of healing in 100% of patients compares favorably with surgical and nonsurgical care series [1,11,16,17,25,28,33,35,36,42,44].…”

Section: Resultsmentioning

confidence: 99%

“…The recurrence rate of ABCs after traditional surgical treatments ranges from 12% to 71% (71% in children \ 10 years) with 90% detected within 2 years of surgical treatment [11,16,17,25,28,35,42,44]. Recurrence is particularly associated with juxtaphyseal locations of ABCs in skeletally immature patients [16].…”

mentioning

confidence: 99%

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Percutaneous Doxycycline Treatment of Aneurysmal Bone Cysts With Low Recurrence Rate: A Preliminary Report

Shiels

Mayerson

2013

Clinical Orthopaedics &Amp; Related Research

105

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Section: Resultsmentioning

confidence: 82%

Section: Resultsmentioning

confidence: 99%

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Percutaneous Doxycycline Treatment of Aneurysmal Bone Cysts With Low Recurrence Rate: A Preliminary Report

Shiels

Mayerson

2013

Clinical Orthopaedics &Amp; Related Research

105

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“…In a case series of 40 patients, Gibbs et al reported local control rates of nearly 90 % after a median 7.2-year follow-up by curettage and high-speed burr without the use of liquid nitrogen, phenol, or other adjuvants [30]. Dormans et al reported that their surgical technique, which included the use of a highspeed burr resulted in an 82 % cure rate [31]. Wang et al concluded that high-speed burr in conjunction with curettage and bone graft was a reasonable approach to ABC treatment as they reported only one recurrence out of 31 patients in their case series.…”

Section: High Speed Burrmentioning

confidence: 99%

Current management of aneurysmal bone cysts

Park

Yang

Sheppard

et al. 2016

Curr Rev Musculoskelet Med

165

236

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Aneurysmal bone cysts (ABCs) are benign bone lesions arising predominantly in the pediatric population that can cause local pain, swelling, and pathologic fracture. Primary lesions, which constitute roughly two thirds of all ABCs, are thought to be neoplastic in nature, with one third of ABCs arising secondary to other tumors. Diagnosis is made with various imaging modalities, which exhibit characteristic features such as Bfluid-fluid levels,^although biopsy is critical, as telangiectatic osteosarcoma cannot be excluded based on imaging alone. Currently, the standard of care and most widely employed treatment is intralesional curettage. However, tumor recurrence with curettage alone is common and has driven some to propose a multitude of adjuvants with varying efficacy and risk profiles. Historically, therapies such as en bloc resection or radiation therapy were utilized as an alternative to decrease the recurrence rate, but these therapies imposed high morbidity. As a result, modern techniques now seek to simultaneously reduce morbidity and recurrence, the pursuit of which has produced preliminary study into minimally invasive percutaneous treatments and medical management.

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“…Young age has been associated with a higher risk of recurrence [1,2,10,18,19]. However, this remains controversial because at least one recent study suggests age does not predict recurrence [8].…”

Section: Introductionmentioning

confidence: 96%