Surgical stabilization of pathological neoplastic fractures

Colyer, Robert A.

doi:10.1016/s0147-0272(86)80005-8

Cited by 31 publications

(11 citation statements)

References 38 publications

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“…The overall rates of postoperative local complications vary widely with local complication rates ranging from less than 5% to more than 25% [5,11,23,29]. The local complication rate in this study of 5.6% is at the lower end of the scale and is comparable to the 3.4% reported by Wedin et al [26].…”

Section: Discussionsupporting

confidence: 67%

Treatment results of pathological fractures of the long bones: a retrospective analysis of 88 patients

Sarahrudi

Hora

Heinz

et al. 2006

International Orthopaedics (SICOT)

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Due to the advances in oncological therapy, the life expectancy of patients with malignant tumours and the incidence of pathological fractures have increased over the last decades. Pathological fractures of the long bones are common complications of metastatic disease; however, the outcome of different surgical techniques for the treatment of these fractures has not been clearly defined. The aim of this study was to evaluate differences in patient's survival and postoperative complications after the treatment of pathological fractures of the long bones. Eighty-eight patients with 96 pathological fractures of the long bones were analysed retrospectively. Seventy-five patients with 83 fractures received surgical treatment. The operative treatments used were intramedullary fixation, gliding screws, plate osteosynthesis or arthroplasty. Five patients were still alive at the end of data collection at a median time of 42.5 months, and 16.2% survived 1 year, 7% 2 years and 4% more than 3 years postoperatively. All surgically treated patients had a reduction of local pain and were able to walk after the operation. The overall rate of complications was 8%. Early palliative treatment of pathological fractures of the long bones is indicated in most patients in the advanced stage of metastatic disease. The low complication rate, reduction of local pain and early mobilisation justify the surgical stabilisation of fractures in this cohort of patients.

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Section: Discussionsupporting

confidence: 67%

Treatment results of pathological fractures of the long bones: a retrospective analysis of 88 patients

Sarahrudi

Hora

Heinz

et al. 2006

International Orthopaedics (SICOT)

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“…According to the literature, bone-related complications are the most likely to occur, although the reported data vary widely. Some studies found fixation failures in 4.7-9.2% of all operations; others found 19% osteosynthesisrelated complications and 19% tumor-related complications [6,8,[11][12][13]. We found bone-related complications after 20% of all operations (n ‫ס‬ 110) of which 11% was osteosynthesis-and 10% tumor-related.…”

Section: Discussionmentioning

confidence: 51%

Operative management of impending pathological fractures: A critical analysis of therapy

et al. 1997

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“…Orthopaedic surgery represents another and often complementary type of palliative treatment in patients with MRCC and osteolytic lesions to the shoulder girdle and/or humerus [12,13]. If only a single metastasis is detectable and the patient's expected life span is considered to be long, it may be worthwhile to resect the bone and soft tissue mass with a wide margin.…”

Section: Discussionmentioning

confidence: 99%