Surgical site fire caused by alcohol and diathermy

Kaya, Burak; Işılgan, Servet Elçin; Çerkez, Cem; Ulusoy, Sinan; Serel, Savaş

doi:10.1007/s00238-014-0980-2

Cited by 1 publication

(1 citation statement)

References 6 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Particularly, the features of peripheral microhemodynamics in rats were studied under different conditions (aging, stress, acute and chronic hypoxia, hypothermia, ischemia/reperfusion syndrome) and on T2DM model [92][93][94][95][96][97][98][99][100][101][102][103][104]. A significant number of studies was aimed at investigation of the effect of physiologically active compounds and pharmacological substances on the processes occurring in skin microvascular bed in animals [105][106][107][108][109][110]. It should be noted that microcirculation changes under stimuli were estimated only by the total skin perfusion in most animal studies.…”

Section: Investigation Of Microcirculation Disorders In Animals On Mo...mentioning

confidence: 99%

Skin Microhemodynamics and Mechanisms of Its Regulation in Type 2 Diabetes Mellitus

et al. 2022

View full text Add to dashboard Cite

The review presents modern ideas about peripheral microhemodynamics, approaches to the ana-lysis of skin blood flow oscillations and their diagnostic significance. Disorders of skin microhemodynamics in type 2 diabetes mellitus (DM) and the possibility of their interpretation from the standpoint of external and internal interactions between systems of skin blood flow regulation, based on a comparison of couplings in normal and pathological conditions, including models of pathologies on animals, are considered. The factors and mechanisms of vasomotor regulation, among them receptors and signaling events in endothelial and smooth muscle cells considered as models of microvessels are discussed. Attention was drawn to the disturbance of Ca 2+ -dependent regulation of coupling between vascular cells and NO-dependent regulation of vasodilation in diabetes mellitus. The main mechanisms of insulin resistance in type 2 DM are considered to be a defect in the number of insulin receptors and impaired signal transduction from the receptor to phosphatidylinositol-3-kinase and downstream targets. Reactive oxygen species plays an important role in vascular dysfunction in hyperglycemia. It is assumed that the considered molecular and cellular mechanisms of microhemodynamics regulation are involved in the formation of skin blood flow oscillations. Parameters of skin blood microcirculation can be used as diagnostic and prognostic markers for assessing the state of the body.

show abstract