Surgical Resection Versus Laparoscopic Radiofrequency Ablation in Patients With Hepatocellular Carcinoma and Child-Pugh Class A Liver Cirrhosis

Abstract

Our data were obtained from a large number of HCC cases and support similar survival rates after HR or LRFA for single HCC nodules on Child-Pugh class A liver cirrhosis, despite a marked increase in HCC recurrence rates after LRFA.

Systematic review and meta-analysis of survival and disease recurrence after radiofrequency ablation for hepatocellular carcinoma

“…In some studies RFA was used in combination with surgery for disease that was otherwise not treatable by resection alone. 45,46,64,65 , whereas those in the resection group were 0-10 per cent 45,46,56,62,64 and 33-51 per cent 45,46,64,65 . None of the eight studies showed significant differences in overall survival rates between the RFA and resection groups.…”

“…None of the eight studies showed significant differences in overall survival rates between the RFA and resection groups. However, patients treated with resection had significantly lower local recurrence rates 46,56,64 , and higher disease-free survival rates 62,65 . Survival rates were rounded to the nearest figure.…”

Laparoscopic Liver Resection for Hepatocellular Carcinoma: Korean Experiences

“…LLR has become a good option for the treatment of HCC. However, LLR for cirrhotic patients is still not widely adopted [13,14]. Many reports have suggested that LLR for small HCC is associated with similar or reduced morbidity in cirrhotic patients compared with an open resection [15,16,17].…”

“…Many reports have suggested that LLR for small HCC is associated with similar or reduced morbidity in cirrhotic patients compared with an open resection [15,16,17]. There may be an advantage of LLR over open liver resection in that the former does not interrupt the collateral vessels on the abdominal wall [14]. Laparoscopic resection of hepatocellular cancers in a cirrhotic liver is feasible and safe in experienced centers, and follow-up data from a few study groups have suggested that the long-term oncologic outcome has not been compromised by the laparoscopic approach compared with open resection [2,4,8,18,19].…”

Recurrent hepatocellular carcinoma successfully treated with laparoscopic thermal ablation

“…Unfortunately, as many as 50-70% of patients who initially undergo HR or thermal ablation (TA) for HCC will experience a recurrence in the remnant liver within 5 years [3][4][5]. To date, salvage HR has been the preferred treatment for intrahepatic recurrence, resulting in further prolongation of survival [5,6].…”