Surgical resection of pulmonary metastases from colorectal adenocarcinoma

Wilking, Nils; Petrelli, Nicholas J.; Herrera, Lemuel; Régal, Anne-Marie; Mittelman, Arnold

doi:10.1007/bf02554142

Cited by 67 publications

(15 citation statements)

References 7 publications

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“…Some studies indicated the number of pulmonary metastases as a prognostic factor. 3,5,7,9,[13][14][15][16][17] Other studies reported the maximum size of lung metastasis, 5,12 disease-free interval, 10,18 prethoracotomy carcinoembryonic antigen (CEA) level, 7,16 hilar/mediastinal lymph node metastasis, 12,13 and the history of other metastatic sites 13 as significant prognostic factors. However, no definitive indications have been established at present.…”

mentioning

confidence: 99%

Extranodal Cancer Deposit at the Primary Tumor Site and the Number of Pulmonary Lesions Are Useful Prognostic Factors After Surgery for Colorectal Lung Metastases

Ishikawa¹,

Hashiguchi²,

Mochizuki³

et al. 2003

Diseases of the Colon &Amp; Rectum

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An extranodal cancer deposit at the primary tumor site is a new significant prognostic factor after resection of lung metastases from colorectal cancer. A two-ranked classification by extranodal cancer deposit and the number of pulmonary lesions can provide useful prognostic information for the treatment of lung metastasis. Surgical resection of pulmonary metastasis is expected to be very useful for patients in Group A.

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confidence: 99%

Extranodal Cancer Deposit at the Primary Tumor Site and the Number of Pulmonary Lesions Are Useful Prognostic Factors After Surgery for Colorectal Lung Metastases

Ishikawa¹,

Hashiguchi²,

Mochizuki³

et al. 2003

Diseases of the Colon &Amp; Rectum

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“…The liver is often the first site of metastasis from colorectal cancer and may be the only site of spread in as many as 30–40% of patients with advanced disease 5 . Lung metastasis is the most common extra‐abdominal site of metastasis and is the second most common site of metastasis 6,7 . Surgery remains the only potential curative treatment for patients with colorectal metastasis, especially for lung metastasis.…”

Section: Discussionmentioning

confidence: 67%

Liver and lung resection for colorectal metastasis

Li¹,

Cheung²,

Ho³

et al. 2007

Surgical Practice

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Aim:To examine the survival benefit of liver and lung resection for colorectal metastasis and the potential prognostic factors that affect patient survival. Methods: All patients who had resection of lung or liver metastasis for colorectal metastasis in Queen Elizabeth Hospital, Hong Kong from 1995 to 2004 were retrospectively reviewed. The overall and disease-free survival was analysed, in particularly between liver and lung metastasis. All factors that may have affected the survival were entered into Cox's proportional hazards regression model to identify significant variables associated with survival. Results: At 5 years, the overall survival of patients who had resection of lung and liver metastasis was 44% and 38%, respectively; the disease-free survival was 26% and 24%, respectively. Overall and disease-free survival of patients with resection of lung metastasis was comparable to those with resection of liver metastasis. The differentiations of primary tumour and time to metastasis were shown to be significant prognostic factors influencing overall survival. Those patients with systemic chemotherapy after resection of colorectal metastasis demonstrated a significantly higher probability of overall survival. Conclusion: Resection of lung and liver metastases from colorectal origin was safe and both procedures improved survival. The use of chemotherapy after resection of metastasis significantly improved the overall survival.

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“…7 Where technically feasible, resection of metastatic deposits in the lungs or liver is advisable. 25,26 The chemotherapeutic agents in use include 5-FU, irinotecan, leucovorin, and the more recent anti-vascular endothelial growth factor, bevacizumab. 7 Radiotherapy finds use in cases of rectal cancer to reduce the risk of local recurrence.…”

Section: Discussionmentioning

confidence: 99%

Colonic cancer in adolescents. A report of three cases

et al. 2009

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Colorectal cancer is a common malignant neoplasm in adults, with a peak incidence of 60–79 years. About 1 million cases of the disease and half a million deaths associated with it are reported world-wide each year. Colorectal cancer, however, is very uncommon in children and adolescents. This is a presentation of 3 cases of colon cancer in Nigerians aged 17 and 19 years. Two of them were adenocarcinoma and the other leiomyosarcoma. The pathogenesis and aspects of management are discussed.

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Surgical resection of pulmonary metastases from colorectal adenocarcinoma

Cited by 67 publications

References 7 publications

Extranodal Cancer Deposit at the Primary Tumor Site and the Number of Pulmonary Lesions Are Useful Prognostic Factors After Surgery for Colorectal Lung Metastases

Extranodal Cancer Deposit at the Primary Tumor Site and the Number of Pulmonary Lesions Are Useful Prognostic Factors After Surgery for Colorectal Lung Metastases

Liver and lung resection for colorectal metastasis

Colonic cancer in adolescents. A report of three cases

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