Surgical Resection of Grade II Astrocytomas in the Superior Frontal Gyrus

Peraud, Aurelia; Meschede, Magnus; Eisner, Wilhelm; Ilmberger, J.; Reulen, H. J.

doi:10.1097/00006123-200205000-00009

Cited by 51 publications

(42 citation statements)

References 27 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Presumably, any unnoticed white matter injury of the primary motor fibers, such as the corticospinal tract, could cause permanent motor weakness. Peraud et al 17 and Kasasbeh et al 7 showed that the distance between the resected area and the precentral gyrus was significantly related to both transient and permanent neurological impairments. Moreover, the anterior-posterior extent of the resected SMA was the most frequently reported risk factor of SMA syndrome in previous reports.…”

Section: Discussionmentioning

confidence: 99%

Risk factor analysis of the development of new neurological deficits following supplementary motor area resection

Kim

et al. 2013

JNS

View full text Add to dashboard Cite

Object Supplementary motor area (SMA) resection often induces postoperative contralateral hemiparesis or speech disturbance. This study was performed to assess the neurological impairments that often follow SMA resection and to assess the risk factors associated with these postoperative deficits. Methods The records for patients who had undergone SMA resection for pharmacologically intractable epilepsy between 1994 and 2010 were gleaned from an epilepsy surgery database and retrospectively reviewed in this study. Results Forty-three patients with pharmacologically intractable epilepsy underwent SMA resection with intraoperative cortical stimulation and mapping while under awake anesthesia. The mean patient age was 31.7 years (range 15–63 years), and the mean duration and frequency of seizures were 10.4 years (range 0.1–30 years) and 14.6 per month (range 0.1–150 per month), respectively. Pathological examination of the brain revealed cortical dysplasia in 18 patients (41.9%), tumors in 16 patients (37.2%), and other lesions in 9 patients (20.9%). The mean duration of the follow-up period was 84.0 months (range 24–169 months). After SMA resection, 23 patients (53.5%) experienced neurological deficits. Three patients (7.0%) experienced permanent deficits, and 20 (46.5%) experienced symptoms that were transient. All permanent deficits involved contralateral weakness, whereas the transient symptoms patients experienced were varied, including contralateral weaknesses in 15, apraxia in 1, sensory disturbances in 1, and dysphasia in 6. Thirteen patients recovered completely within 1 month. Univariate analysis revealed that resection of the SMA proper, a shorter lifetime seizure history (< 10 years), and resection of the cingulate gyrus in addition to the SMA were associated with the development of neurological deficits (p = 0.078, 0.069, and 0.023, respectively). Cingulate gyrus resection was the only risk factor identified on multivariate analysis (p = 0.027, OR 6.530, 95% CI 1.234–34.562). Conclusions Resection of the cingulate gyrus in addition to the SMA was significantly associated with the development of postoperative neurological impairment.

show abstract

Section: Discussionmentioning

confidence: 99%

Risk factor analysis of the development of new neurological deficits following supplementary motor area resection

Kim

et al. 2013

JNS

View full text Add to dashboard Cite

show abstract

“…233 Similarly, in neuro-oncological surgery, many patients display sequelae due to an interruption of the white matter fibers. 234,235 Consequently, during surgery in eloquent areas, the systematic use of intraoperative subcortical stimulation seems mandatory, to better understand underlying anatomo-functional connectivity 141,142,236 and to avoid postsurgical sequelae, which will always be possible despite cortical plastic potential. 237 …”

Section: Surgical Resectionmentioning

confidence: 99%

Brain plasticity: From pathophysiological mechanisms to therapeutic applications

Duffau

2006

Journal of Clinical Neuroscience

301

183

View full text Add to dashboard Cite

“…Near-complete functional recoverability from injury is expected, usually occurring within 4 to 8 weeks (45). However, subtle underutilization of contralateral limbs or delay in speech initiation may persist.…”

Section: Functional Topography Of Premotor Areasmentioning

confidence: 99%