Surgical outcomes of scaphoid fracture osteosynthesis with magnesium screws

Abstract

Objectives This study aims to evaluate the mid-term functional and radiological outcomes of magnesium-based screws in the treatment of scaphoid fractures. Patients and methods Between February 2015 and February 2018, a total of 21 patients (18 males, 3 females; mean age: 28.5±5.8 years; range, 19 to 39 years) with acute scaphoid waist fractures who underwent fracture fixation with biologically degradable magnesium-based compression screws were retrospectively analyzed. Fractures were classified according to the Herbert and Fisher classification. The absence of pain on palpation and painless active range of motion were accepted as the signs of union. Results The mean follow-up was 43.3±5.3 (range, 36 to 52) months. According to the Herbert and Fisher classification, nine patients had type B1 and 12 patients had type B2 scaphoid fractures. Union was achieved in all cases. The mean time to union was 11.2±1.5 (range, 9 to 14) weeks. The mean grip strength, flexion, and extension were 43.57°, 73.57°, and 76.43°, respectively. The grip strength, pinch strength, and range of motion of the operated side were evaluated at the final follow-up visit and compared with the contralateral side (control group). No complication occurred. Any screw was not removed. Conclusion Magnesium-based compression screws can be safely used for acute scaphoid fractures considering their favorable functional and radiological results.

Biodegradable magnesium screw, titanium screw and direct embedding fixation in pedicled vascularized iliac bone graft transfer for osteonecrosis of the femoral head: a randomized controlled study

“…On the other hand, Mg 2+ promotes osteogenesis by promoting inflammatory immune microenvironment in the early stages of osteogenesis. Previous research has found that alginate hydrogels that sustain the release of Mg 2+ contributed to the infiltration and activation of CD68 + macrophages in bone defects during the early stages of bone healing [ 22 , 23 ]. They also found that Mg 2+ promoted the expression of the transient receptor potential cation channel M7 (TRPM7) and nuclear translocation of TRPM7 cleaved kinase fragments (M7CKs), leading to the differentiation of macrophages into the osteogenic subtype as well as promoting bone marrow recruitment and osteogenic differentiation.…”

Porous Mg–Hydroxyapatite Composite Incorporated with Aloe barbadensis Miller for Scaphoid Fracture Fixation: A Natural Drug Loaded Orthopedic Implant

“…The maximum release of 42 mg/L in the pure substrate was observed on the third day of immersion, followed by the aloe vera-loaded sample with 31.5 mg/L and the PLA-coated sample with a 20.7 mg/L Mg ions release rate. Afterward, this release rate seemed to reduce due to the oxide layer developed across the substrate, which restricted the Mg ions release into the immersion medium [66,67]. In the case of the aloe vera loaded sample, a possible reason for an initial burst of Mg ions can be the surface abrasion of the substrate when it was in contact with the corrosion medium.…”

Comparison between bioabsorbable magnesium and titanium compression screws for hallux valgus treated with distal metatarsal osteotomies: A meta-analysis

“…[ 8 ] Recently, alternative bioabsorbable magnesium-based screws have been introduced in orthopedic surgery. [ 9 ] Several studies[ 10 , 11 ] have compared biodegradable magnesium screws with metal screws in patients undergoing DMO. However, whether biodegradable magnesium screws are effective and safe as metallic screws in DMO still remains controversial.…”