Surgical outcomes of anterior trans-obturator mesh and vaginal sacrospinous ligament fixation for severe pelvic organ prolapse in overweight and obese Asian women

Lo, Tsia‐Shu; Tan, Yiap Loong; Khanuengkitkong, Siwatchaya; Dass, Arjun

doi:10.1007/s00192-012-1940-7

Cited by 22 publications

(16 citation statements)

References 27 publications

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“…These properties of the mesh maintain strength, increase flexibility, and decrease load on the tissues9. It also reduced the immunogenic response and offered the greatest biocompatibility18.…”

Section: Discussionmentioning

confidence: 99%

“…However, varieties of LUTS including, de novo overactive bladder89, voiding dysfunction and de novo urinary stress incontinence10 may occur after mesh implantation surgery for POP. It would be difficult to differentiate if the LUTS were brought about by a transient physiologic phenomenon secondary to the surgical procedure or a result of a worrisome reaction to the mesh.…”

mentioning

confidence: 99%

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The immunohistochemical and urodynamic evaluation towards the collagen-coated and non-coated polypropylene meshes implanted in the pelvic wall of the rats

Lin

Yusoff

et al. 2016

Sci Rep

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Our aim is to study the inflammatory response towards the collagen-coated and non-coated polypropylene meshes in rats and the urodynamic investigation post-operatively. Forty-two female Sprague Dawley were divided into 7 groups of 6 rats; Control, Day 7 and 30 for Sham, Avaulta Plus (MPC), Perigee (MP). UDS were taken at days 7 and 30. Mesh with the vagina and bladder wall was removed and sent for immunohistochemical examination. Results showed intense inflammatory reaction on day 7 in the study groups which decreased on day 30. IL-1, TNF-α, MMP-2 and CD31 were observed to decrease from day 7 to day 30. NGF was almost normal on day 30 in all groups. UDS showed no difference in voiding pressure. Both Study and Sham groups had shorter voiding interval (VI) on day 7 but significantly lower in MPC. VI had significantly increased on day 30 in all groups. Voided volume was significantly lower in the mesh groups even when an increase was seen on day 30. In conclusion, the higher levels of IL-1, TNF-α and MMP-2 in collagen-coated polypropylene mesh imply greater inflammation than the non-coated polypropylene mesh. Mesh implantation can lead to shorter voiding interval and smaller bladder capacity.

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Section: Discussionmentioning

confidence: 99%

mentioning

confidence: 99%

The immunohistochemical and urodynamic evaluation towards the collagen-coated and non-coated polypropylene meshes implanted in the pelvic wall of the rats

Lin

Yusoff

et al. 2016

Sci Rep

Self Cite

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“…The outcome measure was the objective cure rate at last follow‐up (≥5 years), defined as POP‐Q ≤ 1 at the anterior vaginal wall and all compartments. Patient feedback on POPDI‐6 with no or mild sensation of protruding abdominal organ (question 3) and no or mild heaviness (question 2) were considered subjective success . For the two patients with recurrent prolapse who underwent repeat surgery before 5‐year follow‐up, assessment on the last visit prior to the second surgery was used in analysis.…”

Section: Methodsmentioning

confidence: 99%

Long‐term outcome of native tissue reconstructive vaginal surgery for advanced pelvic organ prolapse at 86 months: Hysterectomy versus hysteropexy

Pue

Hung

et al. 2015

J of Obstet and Gynaecol

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“…The superiority of using synthetic meshes has been well described in the literature 14-16. One study of the use of synthetic mesh via a double pass on the transobturator foramen also had satisfactory results with regard to anterior wall prolapse 17.…”

Section: Discussionmentioning

confidence: 91%

Sacrospinous ligament suspension with transobturator mesh versus sacral colpopexy for genital prolapse

Juliato

Mazzer

Diniz

et al. 2016

Clinics

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OBJECTIVE:To compare the safety and efficacy of abdominal sacral colpopexy and sacrospinous ligament suspension with the use of vaginal mesh for apical prolapse.METHOD:This retrospective study was conducted from 2005 to 2012 and included 89 women with apical prolapse who underwent surgery. Assessments included pre- and postoperative Pelvic Organ Prolapse Quantification (POP-Q) stage. Rates of objective cure and immediate/late complications were compared.RESULTS:In total, 41 of the 89 women underwent sacrospinous ligament suspension, and 48 of the women underwent abdominal sacral colpopexy. A total of 40.4% of the women had vault prolapse (p=0.9361). Most of them had no complications (93.2%) (p=0.9418). Approximately 30% of the women had late complications; local pain was the main symptom and was found only in women who underwent the abdominal procedure (25.6%) (p=0.001). Only the women who were submitted to the vaginal procedure had mesh exposure (18.4%). The objective success rate and the rate of anterior vaginal prolapse (p=0.2970) were similar for both techniques.CONCLUSION:Sacrospinous ligament suspension was as effective and had a similar objective success rate as abdominal sacral colpopexy for the treatment of apical prolapse. Sacrospinous ligament suspension performed with the use of vaginal mesh in the anterior compartment was effective in preventing anterior vaginal prolapse after surgery.

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Surgical outcomes of anterior trans-obturator mesh and vaginal sacrospinous ligament fixation for severe pelvic organ prolapse in overweight and obese Asian women

Abstract: There was no difference in the objective outcome of sacrospinous ligament fixation with anterior mesh repair surgery among the three Asian BMI categories; however, obese patients showed less improvement in POP symptoms and sexual function.

Cited by 22 publications

References 27 publications

The immunohistochemical and urodynamic evaluation towards the collagen-coated and non-coated polypropylene meshes implanted in the pelvic wall of the rats

The immunohistochemical and urodynamic evaluation towards the collagen-coated and non-coated polypropylene meshes implanted in the pelvic wall of the rats

Long‐term outcome of native tissue reconstructive vaginal surgery for advanced pelvic organ prolapse at 86 months: Hysterectomy versus hysteropexy

Sacrospinous ligament suspension with transobturator mesh versus sacral colpopexy for genital prolapse

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