Surgical Outcomes in Children with Primary Congenital Glaucoma: A 20-Year Experience

Yassin, Sanaa A.; Al-Tamimi, Elham R.

doi:10.5301/ejo.5000784

Cited by 28 publications

(48 citation statements)

References 41 publications

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“…This is in accordance with other published reports, as in the studies by Zagora et al 4 reporting bilateral involvement in 67.1% of PCG cases and the study by Yassin and Al-Tamimi 5 reporting bilateral involvement in 74% of PCG cases and is in contradistinction to other published reports, as in the study by Aziz et al 6 reporting bilateral involvement in 99.3% of cases, the study by Tamcelik et al 7 reporting bilateral involvement in 94.4% of cases, the study by Alanazi et al 8 reporting bilateral involvement in 82.6% of PCG cases, and the study by Taylor et al 1 reporting bilateral involvement in 82% of PCG cases. This higher bilaterality incidence in those reports may be related to the disease severity and underlying genetic abnormality in different communities and ethnic groups.…”

Section: Discussionsupporting

confidence: 93%

Fellow Eye in Unilateral Primary Congenital Glaucoma

Bayoumi

2017

Journal of Current Glaucoma Practice

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AimThis is a report of the incidence of bilateral cases in a cohort of primary congenital glaucoma (PCG) cases and a study of the biometric characteristics of the fellow normal eyes in unilateral cases.Materials and methodsThe charts of 134 PCG children were reviewed, of which 78 cases (58.2%) were found to have bilateral disease. The remaining 56 patients (41.8%) with unilateral disease had their fellow normal eyes compared with an age-matched cohort of ophthalmologically free children.ResultsThere were no differences between the normal fellow eyes of PCG cases and the control eyes in the corneal diameter and central corneal thickness (CCT), whereas the normal fellow eyes of PCG cases had higher intraocular pressure (IOP) and cup/disc (C/D) ratios.ConclusionThe fellow eyes of apparently unilateral PCG cases are not typically normal anatomically like other children unaffected by PCG.Clinical significanceA very high index of suspicion has to be kept for PCG cases that present apparently unilaterally, and meticulous prolonged follow-up is mandatory.How to cite this articleBayoumi NHL. Fellow Eye in Unilateral Primary Congenital Glaucoma. J Curr Glaucoma Pract 2017;11(1):28-30.

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Section: Discussionsupporting

confidence: 93%

Fellow Eye in Unilateral Primary Congenital Glaucoma

Bayoumi

2017

Journal of Current Glaucoma Practice

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“…Significantly higher preoperative IOP (mean 39.47 ± 2.18 mmHg, p = .000016) in infants from group I confirms the critical role of this factor in corneal damage and development of Haab's striae. Early trabeculectomy successfully lowered IOP in both our groups, which is in keeping with the findings of other studies (3,5,12). The mean postoperative IOP below 18 mmHg achieved in group I is also comparable to the results of other studies (13).…”

Section: Discussionsupporting

confidence: 92%

“…Primary trabeculectomy was performed between the age of 7 days and 12 months in all eyes from both groups. Our results do not confirm poor prognosis associated with younger age at diagnosis or surgery in PCG patient and the outcomes are similar to results of other surgeons (2,3,5,8).…”

Section: Discussioncontrasting

confidence: 51%

“…Optic disc assessment is crucial in diagnosis and monitoring of patients with glaucoma (1,3,5,(10)(11)(12). Confocal scanning laser ophthalmoscopy enables objective, quantitative, three-dimensional and reproducible analysis of the optic disc (16).…”

Section: Discussionmentioning

confidence: 99%

“…scarified breaks in Descemet's membrane, corneal edema, or diameter > 11 mm in newborns, > 12 mm in infants below 1 year of age, or > 13 mm at any age), ocular enlargement by progressive myopia or axial length out of keeping with normal growth, or a visual field defect consistent with glaucoma (2). Medical therapy has a limited role and surgery remains the primary therapeutic modality in PCG as a long-term solution for controlling IOP over time (1)(2)(3)(4). The overall therapeutic success after surgery in paediatric glaucoma is variable, depending on the surgical technique and the severity of the disease.…”

Section: Issn 0023-2157 Index 362646mentioning

confidence: 99%

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Evaluation of functional and morphological parameters in eyes with primary congenital glaucoma after trabeculectomy in the long-term follow-up

Koraszewská-Matuszewska¹,

Nita²,

Grzybowski³

2018

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Aim: Primary congenital glaucoma is the most prevalent type of primary paediatric glaucoma. The aim of the study was to estimate functional and morphological parameters in eyes with primary congenital glaucoma, with and without Haab's striae, after classic trabeculectomy in the long-term follow-up. Material and methods: 41 eyes of 27 children aged 7 days to 12 months at primary trabeculectomy with (group I) and without Haab's striae (group II) were reviewed. The best corrected visual acuity, intraocular pressure, central corneal thickness, axial biometry, corneal horizontal diameter, refraction, central endothelial cell density, cup-to-disc ratio, and perimetric mean deviation were analysed. Results: The mean follow-up was 11.4 years. The mean age of operated infants was 5.65 months (group I) and 4.41 months (group II). The mean intraocular pressure before trabeculectomy was significantly higher and endothelial cell density was significantly lower in group I than in group II. The mean myopic refractive error was significantly higher in group I than in group II. There was no difference in best corrected visual acuity, central corneal thickness, axial biometry, corneal horizontal diameter, and perimetric mean deviation between the two groups. Conclusions: The visual function in patients with primary congenital glaucoma after successful trabeculectomy performed in infancy is satisfactory, despite the presence of Haab's striae, impaired corneal structure and decreased endothelial cell density. High intraocular pressure before treatment is an important risk factor for the development of Haab's striae. Classic trabeculectomy is a good first-line surgical procedure in the treatment of primary congenital glaucoma with and without Haab's striae.

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360°-Trabekulotomie beim kindlichen Glaukom

Hoffmann

2019

Ophthalmologe

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Surgical Outcomes in Children with Primary Congenital Glaucoma: A 20-Year Experience

Cited by 28 publications

References 41 publications

Fellow Eye in Unilateral Primary Congenital Glaucoma

Fellow Eye in Unilateral Primary Congenital Glaucoma

Evaluation of functional and morphological parameters in eyes with primary congenital glaucoma after trabeculectomy in the long-term follow-up

360°-Trabekulotomie beim kindlichen Glaukom

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