Surgical margins for excision of primary cutaneous melanoma

Mohs Micrographic Surgery for Melanoma: A Case Series, a Comparative Study of Immunostains, an Informative Case Report, and a Unique Mapping Technique

“…6,15,25,[33][34][35]38,40,48 Mounting evidence supports the concept that while margins for trunk and extremity invasive melanoma may be narrowed without reducing survival, 9,18,19 MIS, especially on the head and neck, may need even wider margins than previously thought. 6,15,25,[33][34][35]38,40,48 Mounting evidence supports the concept that while margins for trunk and extremity invasive melanoma may be narrowed without reducing survival, 9,18,19 MIS, especially on the head and neck, may need even wider margins than previously thought.…”

“…[1][2][3][4][5][6] A dynamic trend toward reducing the size of resection margins continues, buoyed by evidence that extensive surgery aimed at removing subclinical satellite micrometastases beyond the primary contiguous tumor mass neither reduces recurrences, [7][8][9][10][11][12][13][14][15] nor affords a survival advantage. Excisional surgery remains the standard of care for local cutaneous stage 1 and stage 2 MM and for MIS.…”

Utility of Rush Paraffin-Embedded Tangential Sections in the Management of Cutaneous Neoplasms

“…26 Subsequently others have reported their success utilizing the fresh tissue technique, [27][28][29] but it is difficult to know if unnecessarily larger margins are performed in this setting compared to our approach. 26 Subsequently others have reported their success utilizing the fresh tissue technique, [27][28][29] but it is difficult to know if unnecessarily larger margins are performed in this setting compared to our approach.…”

Excision Margins in the Treatment of Primary Cutaneous Melanoma

“…Mohs surgery has been used to establish guidelines for excision margins for recurrent cutaneous melanoma. 11,12 We conducted a systematic review of all randomized controlled trials that have examined the resection margins for cutaneous melanoma comparing narrow margins with wide excision margins. This was done to assess the effect of width of excision margin on melanoma recurrences, disease-free survival, and overall survival.…”

“…12 The results of the United Kingdom Melanoma Study Group excision trial, which compares 1-cm vs 3-cm margins of excision in patients with melanoma 2 mm or thicker, are awaited.…”