Surgical management of spinal solitary fibrous tumor/hemangiopericytoma: a case series of 20 patients

Abstract

recurrence being 36.6 (median 28, range 12-73) months. Our results indicate that grade III is an adverse prognostic factor for both recurrence and over survival (OS) for spinal osseous SFT/HPC, while total resection, especially TES, is a positive prognostic factor. Conclusions Spinal osseous SFT/HPC is a challenging clinical entity given its high local recurrence rate. Surgical management plays a crucial role in the whole treatment of spinal SFT/HPCs and total excision, especially TES, should be strived for whenever possible. Postoperative radiotherapy is recommended to lower the recurrent rate. This study also confirms that pathology grade III is an adverse prognostic factor for spinal osseous SFT/HPCs.

Intradural Extramedullary Spinal Neoplasms: Radiologic-Pathologic Correlation

“…Combining data from recent reviews, there are now 114 cases of spinal SFT/HPC that have been reported in the literature (82)(83)(84). About 10% of CNS lesions occur in the spine, usually in the intradural compartment, although extradural and even intramedullary locations have been reported.…”

A Rare Case of a Thoracic Spinal Hemangiopericytoma

“…The high risk of recurrence of spinal hemangiopericytomas, especially in cases of incomplete resection and high grade tumor, which was the case for our patient, justifies the use of adjuvant radiotherapy [12]. Adjuvant radiotherapy would promote local control of the tumor [1].…”

“…For some authors, the combination of complete tumor resection with radiotherapy would significantly increase the time of tumor recurrence compared to exclusive tumor resection for high-grade tumors (213 months versus 43 months) [13]. Exclusive radiotherapy would be useful in case of nonoperable or small tumor [12]. Chemotherapy alone has not yet been shown to be effective in the treatment of spinal hemangiopericytomas [12].…”

“…Exclusive radiotherapy would be useful in case of nonoperable or small tumor [12]. Chemotherapy alone has not yet been shown to be effective in the treatment of spinal hemangiopericytomas [12]. But anti-angiogenic molecules could produce better results and are still under study [5].…”

Single Solitary Fibrous Tumor Brain Metastasis in a Patient with Simultaneous Adenocarcinoma of the Lung: Case Report and Review of the Literature

“…In a very recent study, Bishop et al reviewed 31 patients treated for SFT in multiple anatomic sites using both surgery and radiation therapy and reported 5-year rates of local control, overall survival, and distant metastatic-free survival as 100%, 95%, and 92%, respectively [33]. In another very recent study including 14 SFT patients treated with postoperative radiation therapy, Jia et al also recommends adjuvant radiotherapy to lower recurrence rate [34].…”