Surgical management of intraventricular central neurocytoma: 92 cases

Qian, Hai-Peng; Lin, Song; Zhang, Mao-zhi; Cao, Yong

doi:10.1007/s00701-012-1446-6

Cited by 36 publications

(43 citation statements)

References 57 publications

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“…It occurs rarely in people younger than 20 years or older than 40 years of age. Most studies have reported that the patients seem to be equally prevalent in either sex (9,16,19,26). In our series, there was no significant sex variation with the male/female ratio being 1:1.1, and the patients ranged from 14 to 59 years of age (mean, 26.3 years).…”

Section: Epidemiologymentioning

confidence: 64%

“…As CNs have a deep-seated intraventricular location, an abundant blood supply, and proximity to critical structures such as the fornix and thalamus, the surgical morbidity and mortality rates were relative high (6,8,(10)(11)(12)(13)(14)19,23). some reported rates of GTR ranged from 31% to 88%, mortality rates varied between 0% and 19%, and morbidity rates varied between 16% and 52% (Table IV).…”

Section: Surgical Strategymentioning

confidence: 99%

“…The incidence of CN is estimated to be only 0.1-0.5% of all primary brain tumors (9,16,19,26). The tumors typically affect adolescents and young adults with the highest incidence occurring in the third decade.…”

Section: Epidemiologymentioning

confidence: 99%

“…One patient received a permanent shunt because of hydrocephalus. authors (10,11,19) advocated that GTR should not be pursued at all costs, and that the patient's quality of life and tumor control should be the ultimate strategies of treatment. We agreed with them, and we incurred a 91% radical removal rate with a permanent postoperative morbidity rate of 13%.…”

Section: Postoperative Coursementioning

confidence: 99%

See 3 more Smart Citations

Operative management of intraventricular central neurocytomas: an analysis of a surgical experience with 32 cases

Chen¹,

Yang²,

Ma³

et al. 2014

Turkish Neurosurgery

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ABSTRACTpatients with central neurocytoma (CN) (11). However, the proximity to the deep critical neural and vascular structures and rich blood supply increase the risk of surgical treatment. Resection of CN is still a challenging procedure for most neurosurgeons. The best selection of the common surgical approaches including transcortical transventricular approach and interhemispheric-transcallosal transventricular approach is still controversial, and the optimal selection and timing of adjuvant radiotherapy and chemotherapy also remain unclear. █ InTRODuCTIOnCentral neurocytomas (CNs) are rare brain tumors of young adults, typically located in deep midline structures near the foramen of Monro (28). The tumors were first described as a distinct clinicopathologic entity by Hassoun et al. in 1982 (9, 11). These well-differentiated tumors with neuronal differentiation have an indolent clinical course. gross total resection (GTR) is the first optimal treatment option for most AIM: To better understand the clinical characteristics of central neurocytoma (CN), as well as to assess the optimum therapeutic schedule. MATERIAl and METhODS:This was a retrospective study of 32 patients with CN who visited our department between January 2008 and January 2013. We analyzed the clinical and radiological presentations, tumor characteristics, surgical strategies, and the prognosis. RESulTS:We performed operation guided by combined intraoperative magnetic resonance imaging (iMRI) and neuronavigation in 25 patients. The iMRI detected residual tumor in 9 cases, and further resection was performed in 5 cases. Total and nearly total tumor resection was achieved in 29 cases (91%). There was no significant difference between transcortical and transcallosal approaches in complications. Two cases (6%) with recurrence received respectively repeat salvage surgery and radiosurgery at 46 and 50 months after surgery. Thirty patients (94%) had excellent functional outcome (Karnofsky Performance Score ≥80) and 28 patients (88%) resumed their occupations.COnCluSIOn: Our study demonstrates radical surgery with excellent neurological outcomes is the primary treatment of CN. The techniques of resection guided by combined iMRI and neuronavigation seems to enable a higher complete resection rate and reduce the morbidity rate during surgery. We suggest careful clinical observation after initial surgery, and repeat salvage surgery or radiosurgery for recurrent CN.

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Section: Epidemiologymentioning

confidence: 64%

Section: Surgical Strategymentioning

confidence: 99%

Section: Epidemiologymentioning

confidence: 99%

Section: Postoperative Coursementioning

confidence: 99%

See 2 more Smart Citations

Operative management of intraventricular central neurocytomas: an analysis of a surgical experience with 32 cases

Chen¹,

Yang²,

Ma³

et al. 2014

Turkish Neurosurgery

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“…In the case of the small ventricle, tumors involving both the frontal horn and midline are best removed by an interhemispheric-transcallosal approach. Some reports further stated that if the ventricular border is close to the surface, such as less than 2 cm or close to the very most lateral border, a transcortical approach should be chosen (8). Decreased incidences of seizure, porencephalic cyst formation, and subdural hygroma were reported to be advantages of interhemispheric-transcallosal approaches (3,4,16).…”

Section: Discussionmentioning

confidence: 99%

Intracranial intraventricular tumors: long-term surgical outcome of 25 patients

Sayyahmelli¹,

Baran²,

Uğurlar³

et al. 2017

Turk J Med Sci

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The aim of this paper is to provide the long-term surgical outcome of patients with intracranial intraventricular tumors. Materials and methods:Twenty-five patients operated on for intraventricular tumors between June 1999 and June 2014 are reviewed. Data from before, during, and after surgery were obtained from the patients' files and patients were followed regularly after surgery. Results:The group of patients comprised 15 females and 10 males with a mean age of 31.6 ± 16 years. The majority were adults and only 3 children were included. Three, 4, and 18 patients had tumors in the 4th, 3rd, and frontal horn of the lateral ventricles, respectively. All patients showed a varying degree of hydrocephalus and headache was the most common presenting symptom. Overall, central neurocytoma was the most common pathological diagnosis. Complications were found in only 4 patients and, in long-term follow-up, 3 patients had died due to the malignant nature or upgrading to a malignant tumor and the rest were alive. Conclusion:Total removal of the intraventricular tumor increases survival because the majority of these tumors are benign and slowgrowing. The type of surgical intervention should be chosen according to the location of the tumor in the ventricular system.

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