Surgical management of hidradenitis suppurativa

Gierek, Marcin; Ochała-Gierek, Gabriela; Kitala, Diana; Łabuś, Wojciech; Bergler‐Czop, Beata

doi:10.5114/ada.2022.115323

Cited by 11 publications

(18 citation statements)

References 42 publications

(49 reference statements)

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“…Skin flaps are associated with the possibility of greater scarring and the possibility of vascular complications, such as necrosis of the skin flap. Split-thickness skin grafts can result in inflexible contracture scars, which can cause contractures, for example, in the armpits [ 14 , 15 ].…”

Section: Introductionmentioning

confidence: 99%

Platelet-Rich Plasma and Acellular Dermal Matrix in the Surgical Treatment of Hidradenitis Suppurativa: A Comparative Retrospective Study

Gierek

Klama-Baryła

Łabuś

et al. 2023

JCM

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(1) Introduction: Hidradenitis suppurativa (HS) is an inflammatory skin disease with recurrent, chronic, painful, and purulent skin lesions. Topical or systemic antibiotics are the most widely used treatments for the management of mild stages of the disease. In chronic cases (Hurley II/III), wide excision of lesions should be considered. During reconstructive surgery, the most problematic aspect is wound closure. Very large excisional wounds require reconstructive techniques such as skin flaps, skin grafts, or both. Surgical methods have their limitations, so reconstructive methods in HS surgery need to be continuously improved through the use of, for example, platelet-rich plasma and acellular dermal matrix; (2) Methods: The aim of this study was to evaluate the clinical outcomes and efficacy of surgical treatment of patients with HS using local skin flaps injected with PRP compared to a group of local skin flaps without platelet-rich plasma injection, an acellular dermal matrix, and split-thickness skin graft co-grafts. Sixty-one patients (29 males and 32 females) were included in the study. Most patients were characterized by Hurley grade III HS; (3) Results: The use of PRP injection in reconstructions (skin flaps) improved healing and reduced the number of complications, a notable trend in this study. A co-graft of acellular dermal matrix and split-thickness skin graft gave better therapeutic results than split-thickness skin graft alone (fewer days in hospital, fewer postoperative complications); (4) Conclusions: PRP injected into skin flaps, co-grafted acellular dermal matrix, and split-thickness skin grafts are good options for the surgical treatment of hidradenitis suppurativa.

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Section: Introductionmentioning

confidence: 99%

Platelet-Rich Plasma and Acellular Dermal Matrix in the Surgical Treatment of Hidradenitis Suppurativa: A Comparative Retrospective Study

Gierek

Klama-Baryła

Łabuś

et al. 2023

JCM

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“…Medical treatment with topical or systemic antibiotics is widely used as a first-line treatment in the management of mild disease at early stages. In chronic (Hurley II/III) cases, surgical methods should be considered [ 10 , 11 ]. Health-related quality of life significantly improves after surgical treatment [ 4 ].…”

Section: Introductionmentioning

confidence: 99%

“…Afterwards, the most problematic aspect is wound closure, due to the wide excision (very large wounds, e.g., bottocks). In such cases, the use of reconstructive techniques is required, such as skin flaps, skin grafts or both [ 10 , 11 ]. The surgical reconstructive techniques for HS are limitless.…”

Section: Introductionmentioning

confidence: 99%

“…Skin flaps are associated with larger scars and the possibility of vascular complications such as skin flap necrosis. Split thickness skin grafts may cause inelastic contraction scars [ 10 , 11 ]. With any surgical wound, the main goal is rapid healing with a minimal scar that will have a long-term natural contour and provide lasting tensile strength.…”

Section: Introductionmentioning

confidence: 99%

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Co-Graft of Acellular Dermal Matrix and Split Thickness Skin Graft—A New Reconstructive Surgical Method in the Treatment of Hidradenitis Suppurativa

et al. 2022

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Hidradenitis suppurativa is a chronic disease that significantly reduces patients’ quality of life. Patients are chronically treated with systemic therapies, which are often ineffective. Surgical treatment for severe cases of hidradenitis suppurativa is one option for affected patients. Surgical treatment has its limitations, and wound closure may be particularly problematic. This requires the use of reconstructive techniques. The methods of choice for wound closure are split-thickness skin grafts or local flaps reconstructions. However, each method has its limitations. This is a presentation of a new reconstructive surgical method in hidradenitis suppurativa surgery: the use of a co-graft of Acellular dermal matrix and split thickness skin graft as a novel method in wound closure after wide excisions, based on two cases. The results of this method are very promising: we achieved very fast wound closure with good aesthetic results regarding scar formation. In this paper, we used several examinations: laser speckle analysis, cutometer tests, and health-related quality of life (QoL) questionnaire to check the clinical impact of this method. Our initial results are very encouraging. ADM with STSG as a co-graft could be widely used in reconstructive surgery. This is a preliminary study, which should be continued in further, extended research.

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“…In patients’ therapy, several methods are used, such as topical treatment, systemic antibiotic therapy, hormones, biologic therapy and surgery [ 13 , 14 , 15 ]. First-line antibiotics therapies are clindamycin and the systemic use of clindamycin and rifampicine [ 2 ].…”

Section: Introductionmentioning

confidence: 99%

Impact of Hidradenitis Suppurativa Surgical Treatment on Health-Related Life Quality

Gierek

Kitala

Łabuś

et al. 2022

JCM

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(1) Background: Hidradenitis suppurativa is a disease that affects the intimacy of patients. This disease reduces the quality of life and functioning of patients in everyday life. The surgical treatment of HS is one of the treatments for HS that can improve the quality of life. (2) Methods: The main goal of this study was to assess quality of life before the surgical treatment and after the surgical treatment of HS at Center for Burn Treatment in Siemianowice Śląskie, Poland, using the EQ-5D-5L survey before the operation and at follow-up (6 months after). (3) Results: The average quality of life measured with the EQ-5D-5L survey before therapy was 39.3 ± 20.1 (min., 0; max., 60; most frequent value, 50), whereas after surgical treatment, the mean quality of life was 89.5 ± 12.5 (min., 50; max., 100; most frequent value, 100). The average increase in the quality of life was 50.2 ± 19.5 (min., 30; max., 100; most frequent value, 30), and it was statistically significant (p < 0.001).

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Surgical management of hidradenitis suppurativa

Cited by 11 publications

References 42 publications

Platelet-Rich Plasma and Acellular Dermal Matrix in the Surgical Treatment of Hidradenitis Suppurativa: A Comparative Retrospective Study

Platelet-Rich Plasma and Acellular Dermal Matrix in the Surgical Treatment of Hidradenitis Suppurativa: A Comparative Retrospective Study

Co-Graft of Acellular Dermal Matrix and Split Thickness Skin Graft—A New Reconstructive Surgical Method in the Treatment of Hidradenitis Suppurativa

Impact of Hidradenitis Suppurativa Surgical Treatment on Health-Related Life Quality

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