Surgical Management of Giant Cell Tumors in Temporomandibular Joint Region Involving Lateral Skull Base: A Multidisciplinary Approach

Shen, Yi; Ma, Chunyue; Wang, Liang; Li, Jun; Wu, Yiqun; Sun, Jian

doi:10.1016/j.joms.2016.04.009

Cited by 13 publications

(8 citation statements)

References 38 publications

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“…It is obvious that the prognosis of these patients was worse than that of those who received surgery alone. At this point, our analysis is largely consistent with previous reports [7] [17].…”

Section: Discussionsupporting

confidence: 93%

Malignant tumours of temporomandibular joint

Yibulayin

Feng

et al. 2020

BMC Cancer

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Background Malignant tumours of the temporomandibular joint (MTTMJ) are extremely rare. Studies describing its unique epidemiology, clinicopathological features, treatment and prognosis comprehensively are limited. To address these issues, current investigation was performed. Methods A retrospective research was carried out by using population-based data from the Surveillance, Epidemiology, and End Results database (1973–2016). Results Data for a total of 734 patients, including 376 men and 358 women, was found. The median age was 47 years. The 5-year and 10-year disease specific survival (DSS) rates were 69.2 and 63.6%, respectively. Significant differences in DSS were found according to age, race, tumour type, AJCC/TNM stage, surgery, radiotherapy, chemotherapy and different treatment modalities (P < 0.05). In the multivariate survival analysis, age > 44 years and AJCC stage III and IV were associated with poor DSS. Conclusion MTTMJ was mostly found in white people with a median age of 47 years without any sex predominance. Patient’s age and AJCC stage was independent predictor of DSS.

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Section: Discussionsupporting

confidence: 93%

Malignant tumours of temporomandibular joint

Yibulayin

Feng

et al. 2020

BMC Cancer

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“…GCTBs of the cranial and facial bones most commonly affect the temporal and sphenoid bones. 14 15 18 19 20 GCTBs of the lateral skull base are often locally aggressive and can invade nearby critical structures. 18 21 It is believed that these tumors arise in these areas because the bones of the mandible, sphenoid, ethmoid, and parts of the temporal bone form largely through the process of endochondral ossification.…”

Section: Discussionmentioning

confidence: 99%

“…Surgical removal of GCTB of the skull with complete resection is the current treatment of choice. 8 14 18 The surgical management of GCTB of the lateral skull base can be difficult because of its proximity to critical neurovascular structures. Although gross total resection of the tumor is ideal, this may not be feasible depending on the extent of structural involvement by the tumor.…”

Section: Discussionmentioning

confidence: 99%

“… 11 12 13 Involvement of the axial skeleton is often associated with increased morbidity because of local infiltration of critical structures and the associated difficulty of complete tumor resection, particularly compared with resection of GCTBs of the appendicular skeleton. 8 14 GCTB of the skull has also been reported to behave in a locally aggressive fashion. 15 Nevertheless, surgery remains the treatment of choice for GCTBs, including those in the skull, with en bloc or wide local excision portending the lowest risk of recurrence and best clinical outcomes in patients.…”

Section: Introductionmentioning

confidence: 99%

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Giant Cell Tumor of the Lateral Skull Base: Diagnostic and Management Options

et al. 2018

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Giant cell tumor of bone (GCTB) is a rare, benign, osteolytic neoplasm that most commonly occurs in early adulthood and often involves the long bones of the body. Although GCTB largely affects the epiphyses of long bones, several reports of GCTB involvement of the cranial and facial bones exist in the literature. In addition to reviewing other reported cases of GCTBs of the lateral skull base in the literature, the authors report here on the clinical presentation, radiographic findings, and neurosurgical management of a patient found to have a GCTB of the middle and infratemporal fossae, which was treated by aggressive en bloc resection of the lateral skull base.

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“…Current treatment options include observation or gross/subtotal resection with or without adjuvant radiation therapy. Gross total resection is the treatment of choice [2,7,18,19]. If compression occurs on critical structures (e.g.…”

Section: Presentation and Managementmentioning

confidence: 99%