Surgical Management of Benign Tumors of the Liver

Kammula, Udai S.; Buell, Joseph F.; Labow, Daniel M.; Rosen, Seth; Millis, J. Michael; Posner, Mitchell C.

doi:10.1385/ijgc:30:3:141

Cited by 61 publications

(54 citation statements)

References 26 publications

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“…Meanwhile, the diagnosis of a malignant lesion of the liver often leads to decisions to undertake more aggressive therapies such as surgical resection, liver transplantation, percutaneous ablative therapies or systemic chemotherapy [36][37][38].…”

Section: Relevancementioning

confidence: 99%

PET/CT-guided biopsy of liver lesions

Cerci

Huber

Bogoni

2014

Clin Transl Imaging

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Positron emission tomography/computed tomography (PET/CT) has had a great impact in oncology; in this field, PET/CT-guided biopsy finds application in the evaluation of liver lesions, among others. The indication for this procedure should be individualized and taken into account the level of suspicion of malignancy and the need for diagnostic confirmation. PET/CT-guided biopsy is feasible and may optimize the diagnostic yield of image-guided interventions.

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Section: Relevancementioning

confidence: 99%

PET/CT-guided biopsy of liver lesions

Cerci

Huber

Bogoni

2014

Clin Transl Imaging

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“…5 The surgical procedure is the choice of the individual surgeon -the commonest being enucleation and resection. 5,6 Massive blood loss can occur during surgery and may result in an operative mortality. Though liver resections can be safely accomplished in specialised units, occasional postoperative complications (bile leak) do occur.…”

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confidence: 99%

Giant Haemangioma of the Liver: Is Enucleation Better than Resection?

Singh

Kapoor

Sahni

et al. 2007

annals

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Ann R Coll Surg Engl 2007; 89: 490-493 490Haemangioma is the commonest benign liver tumour with an incidence of 0.4-7.3% in autopsy series. 1 With the increasing use of imaging modalities, asymptomatic giant haemangiomas (> 4 cm in size) are detected more frequently. These lesions can, at times, present a diagnostic dilemma. 2There is considerable controversy regarding the ideal treatment of giant haemangiomas of the liver. Some authors, on the basis of long-term follow-up of such lesions, propose that most of these lesions do not require any treatment. 3,4 Others have treated these lesions surgically, citing symptoms of the patient, increase in size and an occasional case of rupture, or diagnostic uncertainty. 5The surgical procedure is the choice of the individual surgeon -the commonest being enucleation and resection. 5,6 Massive blood loss can occur during surgery and may result in an operative mortality. Though liver resections can be safely accomplished in specialised units, occasional postoperative complications (bile leak) do occur. Enucleation may represent a safer surgical option with fewer complications for the treatment of haemangiomas, especially in centres with limited experience in liver resections.We reviewed our experience of the surgical treatment of giant haemangiomas of the liver with regard to presentation, indications and outcome. We also compared our results with those published in the literature. Patients and MethodsThe details of all patients undergoing surgical treatment of liver haemangiomas at the Department of Gastrointestinal There is continuing debate regarding the ideal method of surgical treatment for liver haemangiomas, with some surgeons favouring enucleation over liver resection.

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“…Nowadays, surgery is a routine treatment modality for benign hepatic lesions. Zhi-Qiang Huang has reported two cases of intrahepatic bile duct stone (the secondary common benign hepatic lesion in China) treated with left external [19][20][21][22][23] . In this study, retrospectively investigated 827 consecutive cases of benign hepatic lesions were retrospectively investigated in the Chinese PLA General Hospital, which provides some evidence-based data about the improved hepatectomy techniques.…”

Section: Discussionmentioning

confidence: 99%

Liver resection for benign hepatic lesions: A retrospective analysis of 827 consecutive cases

Feng¹,

Huang²,

Xu³

et al. 2008

WJG

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AIM:To analyze the operative and perioperative factors associated with hepatectomy of benign hepatic lesions. METHODS: A total of 827 condecutive cases of benign hepatic lesion undergoing hepatectomy from January 1986 to December 2005 in the Chinese PLA General Hospital were investigated retrospectively according to their medical documentation. RESULTS: The effect of operative and perioperative factors on the outcome of patients were analyzed. Of the 827 cases undergoing hepatectomy for more than 3 liver segments accounted for 22.1%, 316 (38.21%) required transfusion of blood products during operation. The average operating time was 220.59 ± 109.13 min, the average hospital stay after operation was 13.55 ± 9.38 d. Child-Pugh A accounted for 98.13%. The postoperative complication rate was 13.54% and the in-hospital mortality rate was 0.24%. Multivariate analysis showed that operating time (P = 0.004, OR = 1.003) and albumin value (P = 0.040, OR = 0.938) were the independent predictors of morbidity and indicated that operating time, blood transfusion, complication rate, and LOS had a trend to decrease. CONCLUSION: Hepatectomy for benign hepatic lesions can be performed safely with a low morbidity and mortality, provided that it is carried out with optimized perioperative management and an innovative surgical technique.

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Surgical Management of Benign Tumors of the Liver

Cited by 61 publications

References 26 publications

PET/CT-guided biopsy of liver lesions

PET/CT-guided biopsy of liver lesions

Giant Haemangioma of the Liver: Is Enucleation Better than Resection?

Liver resection for benign hepatic lesions: A retrospective analysis of 827 consecutive cases

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