Surgical management of acquired anterior glottic web: a systematic review

Abstract

BackgroundAcquired anterior glottic web poses a significant challenge to laryngologists given its propensity to recur following treatment, and there are a wide variety of described techniques.MethodsA systematic review of the medical literature was undertaken in order to identify all articles pertaining to the management of acquired anterior glottic web.ResultsThirteen studies meeting the inclusion criteria were identified and analysed. All were retrospective series, with varying surgical techniques and outcome measures. Only two studies reported on the use of topical mitomycin C.ConclusionMucosal graft techniques and keel placement appear to improve success rates, but both carry risks and disadvantages. Based on the available evidence, the use of topical agents such as mitomycin C cannot be recommended in the management of acquired anterior glottic web.

How I Do It: A Novel Technique for Endoscopic Placement of Stent in Management of Anterior Glottic Webs

“…In-office removal of the keel has been previously reported. 5 In our series, two patients' keels were removed in the office under topical anesthesia without any complication, reinforcing this as an alternative approach.…”

Development of a Bioinspired, Self‐Adhering, and Drug‐Eluting Laryngotracheal Patch

“…In addition to expanding the possible dose and durations for steroid treatment, this approach could reduce currently necessary injections. Similarly, few effective adjuvant therapies are available for glottic webs beyond keels and stents 47 . Interest in improved management of webs is evidenced by recent studys exploring bovine pericardium as a potential graft material and advanced surgical closure techniques 48, 49 .…”

“…Similarly, few effective adjuvant therapies are available for glottic webs beyond keels and stents. 47 Interest in improved management of webs is evidenced by recent studys exploring bovine pericardium as a potential graft material and advanced surgical closure techniques. 48,49 Our novel patch could fill this role and be used with or without accompanying drug delivery.…”

Anterior Glottic Web Secondary to Bioenzyme Toxicity

“…by infection, laryngeal trauma due to frequent or prolonged intubation, external trauma, surgical trauma, inhalation of harmful substances, or laryngopharyngeal reflux. [1][2][3][4] We report the first known case of a suspected oral supplement bioenzyme aspiration causing an anterior glottic web.…”