Surgical management of a giant parathyroid adenoma through minimal invasive parathyroidectomy. A case report

Sahsamanis, Georgios; Gkouzis, Konstantinos; Samaras, Stavros; Pinialidis, Dionysios; Dimitrakopoulos, Georgios

doi:10.1016/j.ijscr.2017.01.064

Cited by 17 publications

(17 citation statements)

References 16 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…The depth/width ratio was 0.96, which represents adenoma, rather than carcinoma [6]. Although the giant parathyroid adenoma measured 4.0 cm in our case, we were able to successfully use a minimal excision technique [7].…”

Section: Discussionmentioning

confidence: 60%

A Case Report of A Giant Parathyroid Adenoma Presenting with A Brown Tumor

Enomoto

Fukumoto

Osaka

et al. 2020

Preprint

View full text Add to dashboard Cite

Abstract Background: Giant parathyroid adenoma presenting with a brown tumor is considered extremely rare.Case Presentation: A 21-year-old woman presented to the clinic with persistent pain in her right knee. A radiographic examination showed an osteolytic lesion in her right tibia. Blood laboratory tests revealed that serum calcium and intact parathyroid hormone were increased significantly. Physical examination showed a 3-cm, firm, immovable lump in her neck. Ultrasonography of the patient’s neck revealed a 3.5-cm, well-circumscribed mass with a homogeneous internal texture. Computed tomography also showed a localized tumor with clear margins. The 99mTc-MIBI scintigraphy showed a hot spot in the right inferior gland. Based on these findings we judged that she had giant parathyroid adenoma presenting with a brown tumor. We ruled out the possibility of carcinoma based on image studies. We performed a parathyroidectomy via a small incision. The excised parathyroid gland weighed 10.3 g. The patient’s postoperative course was unremarkable. Conclusions: Giant parathyroid adenoma presenting with a brown tumor is extremely rare. Accordingly, the differentiation between giant adenoma and parathyroid carcinoma is crucial. However, we could rule out the possibility of carcinoma based on imaging studies, including ultrasonography and computed tomography. As a result, we performed successful parathyroidectomy with a small incision.

show abstract

Section: Discussionmentioning

confidence: 60%

A Case Report of A Giant Parathyroid Adenoma Presenting with A Brown Tumor

Enomoto

Fukumoto

Osaka

et al. 2020

Preprint

View full text Add to dashboard Cite

show abstract

“…The main symptoms are acute abdominal pain, constipation, vomiting and nausea. 5 In our case, the hypercalcemia due to primary hyperparathyroidism was diagnosed after an episode of pancreatitis. This association is reported in <10% of cases in the literature.…”

Section: Discussionmentioning

confidence: 68%

“…Normocalcemic hyperparathyroidism can also be seen and should not be confused with secondary hyperparathyroidism. 5 The diagnostic of primary hyperparathyroidism is based on biochemical criteria; however, the localization of the pathologic parathyroid gland and the planning of the surgical management require imaging methods.…”

Section: Discussionmentioning

confidence: 99%

“…7 It uses the absorption of radiotracer from hyperactive parathyroid tissue, in order to localize abnormal parathyroid glands. 5 Technetium-99m ( 99m Tc) sestamibi has been introduced for parathyroid imaging in 1989 and the technique has been subject to several changes with an important improvement of its efficiency. Alabdulkarim found in his study evaluating this imaging method, a sensitivity and specificity of 98.1 and 97%, respectively.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

Giant Parathroid Adenoma With Thoracic Extension: A Case Report

Mbarek¹,

Belaid²,

Khamassi³

et al. 2018

Otolaryngol Open J

View full text Add to dashboard Cite

A 31-year-old female patient was addressed to our consultation for management of hypercalcemia secondary to primary hyperparathyroidism. The physical examination results were normal. The technetium sestamibi (99m Tc MIBI) parathyroid scintigraphy showed a large fixation area next to the inferior pole of the left lobe of the thyroid. Cervical computed tomography (CT) scan showed a 6 cm tissue lesion in the inferior pole of the thyroid's left lobe. The patient was operated through a classical cervical incision, extracting successfully a 6 cm brown lesion. The histopathological study has confirmed the diagnosis of a giant parathyroid adenoma weighing 84 g.

show abstract

“…Primary hyperparathyroidism presents with a variety of symptoms such as neuromuscular weakness, fatigue, bone disease, recurrent nephrolithiasis and nephrocalcinosis, psychiatric disorders, decreased concentration and memory loss, nausea, vomiting, constipation and bradycardia [ 8 – 12 ]. During the last decades, patients have presented with profound symptoms of severe hypercalcemia and bone disease.…”

Section: Discussionmentioning

confidence: 99%

A Rare Case of Primary Hyperparathyroidism Caused by a Giant Solitary Parathyroid Adenoma

et al. 2018

View full text Add to dashboard Cite

Patient: Female, 73Final Diagnosis: Primary hyperparathyroidismSymptoms: Bone fractures • nephrolithiasis • palpable mass • weaknessMedication: —Clinical Procedure: OperationSpecialty: SurgeryObjective:Rare diseaseBackground:Solitary parathyroid adenomas are the leading cause of primary hyperparathyroidism in 0% to 85% of cases. Diagnosis of parathyroid adenoma is based on typical clinical presentation of hypercalcemia, biochemical profile, and modern imaging studies. The purpose of this article is to present the diagnostic and therapeutic approach used for a 73-year-old female patient with a giant parathyroid adenoma measuring 5×2.5×2.5 cm and weighing 30 grams.Case Report:A 73-year-old female was referred to the outpatient clinic of our Surgical Department with the diagnosis of primary hyperparathyroidism. The patient suffered from typical symptoms of hypercalcemia such as weakness, bone disease, and recurrent nephrolithiasis; she had a painless cervical mass for 5 months. Primary hyperparathyroidism was confirmed based on the patient’s biochemical profile, which showed increased levels of serum calcium and parathyroid hormone. SestaMIBI scintigraphy with 99mTechnetium and cervical ultrasonography revealed a large nodule at the inferior pole of the right lobe of the thyroid gland. Intraoperatively, a giant parathyroid adenoma was found and excised. Additionally, levels of intact parathyroid hormone (IOiPTH) were determined intraoperatively and a 95% reduction was found, 20 minutes after the removal of the adenoma.Conclusions:This is an extremely rare case of a giant solitary parathyroid adenoma. Diagnosis of a giant hyperfunctioning solitary parathyroid adenomas was based on clinical presentation, biochemical profile, and imaging studies. Selective treatment was based on surgical excision combined with IOiPTH levels measurement.

show abstract

Surgical management of a giant parathyroid adenoma through minimal invasive parathyroidectomy. A case report

Cited by 17 publications

References 16 publications

A Case Report of A Giant Parathyroid Adenoma Presenting with A Brown Tumor

A Case Report of A Giant Parathyroid Adenoma Presenting with A Brown Tumor

Giant Parathroid Adenoma With Thoracic Extension: A Case Report

A Rare Case of Primary Hyperparathyroidism Caused by a Giant Solitary Parathyroid Adenoma

Contact Info

Product

Resources

About