Surgical management for squamous cell carcinoma of vulva

Abstract

To analyze our surgical management and the result of squamous cell carcinoma (SCC) of vulva. Retrospectively, we collected 38 cases of SCC; 17 cases of them were early SCC and 21 cases were locally advanced. The patients underwent primary surgery. The survival was estimated using Kaplan-Meier analysis and the log rank test. The mean age was 60.78 years. Total vulvectomy was performed in all patients. Superficial and deep incision of bilateral inguinal lymphadenectomy was performed by separates incisions for SCC infiltrating more than 1mm. The average tumor size was 53 mm (10 to 140mm). Morbidity was 42.1%. Lateral resection margin ≥8mm was obtained in 57.1%. Eighteen patients benefited from adjuvant radiotherapy. The follow-up median was 19.4 months (6 to 61.5 month) with 05 recurrences in 12 months. The survival using the Kaplan-Meyer analysis at 5 years, was 62.1% (71.2%N- vs 46.7%N+; p = 0.13). We identified two groups for locally advanced vulva cancer. Primary surgery keeps its place. Neo adjuvant radio chemotherapy followed by surgery is the alternative treatment for locally extensive lesions.

Vulvar cancer in Iran: Retrospective study over 20 years (1998-2018)

“…It was resemble to Amavi et al . [9] study. Mean age in US[10] was 68 years and 70 years in Ciszko study[11] [Table 5].…”

“…According to FIGO, in Ciszko study[11], 68% of cases vulvar cancer was detected in II, III or IVa stage. Moreover, 39% of patients in Amavi study[9] and 53.3% in Butt et al . [3] were at stages III and IV.…”

Modified Radical Vulvectomy for Carcinoma Vulva: Are We Following Key Quality Standards?

“…Cancer of the vulva is one of the rare gynecological cancers and accounts for 4% of all female genital cancers with an incidence of 2 per 100,000 women/year. 2,3 Primary surgery followed by radiotherapy remains the mainstay of therapy in stage Ib to III disease. 4,5 The traditional butterfly incision, en bloc radical vulvectomy of a vulval lesion with large areas of normal tissue and bilateral lymphadenectomy of inguinofemoral and pelvic nodes, has undergone modifications in recent years, aiming at the conservation of healthy tissues.…”