Surgical Implications of Primary Gastrointestinal Lymphoma of Childhood

Primary gastrointestinal tract lymphoma in the pediatric patient: review of 265 patients from the SEER registry

“…By univariate analysis, local or regional stage of disease was associated with higher 10-year survival, which is consistent with previous reports [20]. However, in our cohort, the increase in survival was not significant, but there was a trend toward significance (P = .067).…”

“…Ladd and Grosfeld [3] found in a series of 30 pediatric PGTL patients that surgical resection for localized disease was associated with an 80% 2-year survival. Fleming et al [20] also advocated complete surgical resection in NHL in childhood based on a series of 54 patients. Specifically, in Burkitt lymphoma, Stovroff et al [21] showed there to be improved survival outcomes in surgically resected children.…”

Spontaneous Intestinal Perforation Due to Non-Hodgkin's Lymphoma: Evaluation of Eight Cases

“…4, 6, and 7). Surgical treatment for small intestinal and colon lymphoma for localized lesions is resection of the affected segment and mesentery and primary anastomosis [6,10,23,24]. For synchronous lymphoma, curative resection may not be performed effectively.…”

Intussusception due to non Hodgkin's lymphoma; different experiences in two children: two case reports

“…Complete resection of the tumor was shown to have the added advantage of avoiding bowel perforation, gastrointestinal hemorrhage or the tumor-lysis syndrome after the initiation of chemotherapy [17-19]. In NHL involving the bowel, surgical resection has been associated with improved outlook by complete resection in localized disease confined to the bowel wall and diagnostic biopsy in advanced diseases [20]. Hence, with high suspicion of lesions, considering the age of the child and the bowel involvement, resection of the diseased bowel may be the single most important decision in salvaging these children.…”