Surgical findings and outcome for dairy cattle with jejunal hemorrhage syndrome: 31 cases (2000–2007)

Peek, Simon F.; Santschi, Elizabeth M.; Livesey, M. A.; Prichard, Mike A.; McGuirk, Sheila M.; Brounts, Sabrina H.; Edwards, Ryland B.

doi:10.2460/javma.234.10.1308

Cited by 16 publications

(31 citation statements)

References 5 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…If STECs do cause disease in mature cattle, the most likely candidates are diseases with unclear etiologies such as JHS [13]. Current treatments for JHS include an aggressive medical and surgical therapy that can be effective, but the prognosis for long term survival relies upon early detection [14]. An alternative therapy for on-farm treatment is required for animals that are not detected or for rapidly developing cases.…”

Section: Introductionmentioning

confidence: 99%

Mouldy feed, mycotoxins and Shiga toxin - producing Escherichia coli colonization associated with Jejunal Hemorrhage Syndrome in beef cattle

Baines¹,

Erb²,

Turkington

et al. 2011

BMC Vet Res

View full text Add to dashboard Cite

BackgroundBoth O157 and non-O157 Shiga toxin - producing Escherichia coli (STECs) cause serious human disease outbreaks through the consumption of contaminated foods. Cattle are considered the main reservoir but it is unclear how STECs affect mature animals. Neonatal calves are the susceptible age class for STEC infections causing severe enteritis. In an earlier study, we determined that mycotoxins and STECs were part of the disease complex for dairy cattle with Jejunal Hemorrhage Syndrome (JHS). For STECs to play a role in the development of JHS, we hypothesized that STEC colonization should also be evident in beef cattle with JHS. Aggressive medical and surgical therapies are effective for JHS, but rely on early recognition of clinical signs for optimal outcomes suggesting that novel approaches must be developed for managing this disease. The main objective of this study was to confirm that mouldy feeds, mycotoxins and STEC colonization were associated with the development of JHS in beef cattle.ResultsBeef cattle developed JHS after consuming feed containing several types of mycotoxigenic fungi including Fusarium poae, F. verticillioides, F. sporotrichioides, Penicillium roqueforti and Aspergillus fumigatus. Mixtures of STECs colonized the mucosa in the hemorrhaged tissues of the cattle and no other pathogen was identified. The STECs expressed Stx1 and Stx2, but more significantly, Stxs were also present in the blood collected from the lumen of the hemorrhaged jejunum. Feed extracts containing mycotoxins were toxic to enterocytes and 0.1% of a prebiotic, Celmanax Trademark, removed the cytotoxicity in vitro. The inclusion of a prebiotic in the care program for symptomatic beef calves was associated with 69% recovery.ConclusionsThe current study confirmed that STECs and mycotoxins are part of the disease complex for JHS in beef cattle. Mycotoxigenic fungi are only relevant in that they produce the mycotoxins deposited in the feed. A prebiotic, Celmanax Trademark, acted as a mycotoxin binder in vitro and interfered with the progression of disease.

show abstract

Section: Introductionmentioning

confidence: 99%

Mouldy feed, mycotoxins and Shiga toxin - producing Escherichia coli colonization associated with Jejunal Hemorrhage Syndrome in beef cattle

Baines¹,

Erb²,

Turkington

et al. 2011

BMC Vet Res

View full text Add to dashboard Cite

show abstract

“…The condition has been reported in beef and dairy breeds, with a predilection for Holstein and Brown Swiss. 46,47,[54][55][56] Brown Swiss were significantly overrepresented in 1 study. 56 Clinical signs of this peracute disease include recumbency, dehydration, shock, abdominal distension, anorexia, abdominal pain, and lack of feces or the production of tarry feces with blood clots.…”

Section: Clinical Signsmentioning

confidence: 99%

“…The most common clinical findings are: hemorrhagic diarrhea with clots of dark blood or absence of feces, colic, tachycardia, white mucosa, right ventral distension, rumen atony, lack of intestinal motility, and variable right-sided ping. 46,47,56,57 Abdominal examination per rectum may reveal distended jejunum, depending on the location of the blood clot. A mass can also be palpated in some animals.…”

Section: Clinical Signsmentioning

confidence: 99%

“…46 In another study, medical treatment was successful in 2 out 5 animals and 18 out of 30 animals survived after a surgical procedure; resection anastomosis (14 out of 20), clot fractionation (4 out of 18), and intraoperative euthanasia (2). 47 Peek and colleagues 56 described the surgical findings and outcomes of 31 dairy cattle. Eighteen of the 31 (58%) that were surgically treated were discharged.…”

Section: Postoperative Care and Prognosismentioning

confidence: 99%

See 1 more Smart Citation

Intestinal Surgery

Desrochers

Anderson

2016

Veterinary Clinics of North America: Food Animal Practice

View full text Add to dashboard Cite

A wide variety of disorders affecting the intestinal tract in cattle may require surgery. Among those disorders the more common are: intestinal volvulus, jejunal hemorrhage syndrome and more recently the duodenal sigmoid flexure volvulus. Although general principles of intestinal surgery can be applied, cattle has anatomical and behavior particularities that must be known before invading the abdomen. This article focuses on surgical techniques used to optimize outcomes and discusses specific disorders of small intestine. Diagnoses and surgical techniques presented can be applied in field conditions.

show abstract

“…However, if STECs do cause disease in mature cattle, the most likely candidates are diseases with unclear etiologies such as JHS (Puntenney et al, 2003). Current treatments for JHS include an aggressive medical and surgical therapy that can be effective, but the prognosis for long term survival relies upon early detection (Peek et al, 2009).…”

Section: Stec In the Beef Chainmentioning

confidence: 99%

STEC in the beef chain: One health approach

Nastasijević¹,

Mitrovic²,

Janković³

2014

Tehnologija mesa

View full text Add to dashboard Cite

Surgical findings and outcome for dairy cattle with jejunal hemorrhage syndrome: 31 cases (2000–2007)

Abstract: Survival rates were higher than those in other reports. Prompt celiotomy and resolution by use of manual massage were associated with higher survival rates. In this population, JHS recurred in 7 of 18 short-term survivors.

Cited by 16 publications

References 5 publications

Mouldy feed, mycotoxins and Shiga toxin - producing Escherichia coli colonization associated with Jejunal Hemorrhage Syndrome in beef cattle

Mouldy feed, mycotoxins and Shiga toxin - producing Escherichia coli colonization associated with Jejunal Hemorrhage Syndrome in beef cattle

Intestinal Surgery

STEC in the beef chain: One health approach

Contact Info

Product

Resources

About