Surgical excision of eyelid tumors and subsequent ophthalmoplastic reconstruction

Therapy options for ocular basal cell carcinoma — possibilities and limitations

“…Most commonly the first line treatment of the periocular BCC involves a thorough surgical removal including both: a) wide surgical excision followed by postoperative pathologic evaluation of margins, and b) Mohs micrographic surgery with comprehensive intraoperative margin control (frozen section margin control) [18,19]. Complete surgical tumor excision (R0) followed with histopathological assessment of the tumor margins still represents the gold standard [20]. Determining a safety margin for periocular BCC is challenging as each millimeter of healthy tissue holds significance for subsequent functional reconstruction.…”

“…Therefore, intraoperative margin control involves assessing the tumor and its borders before reconstruction. Mohs micrographic surgery is the least invasive surgical technique, involving systematic microscopic examination of tissue samples taken directly from the patient, and it enables evaluation of the entire excision margin during the surgical procedure [18][19][20]. Tissue is progressively excised following a specific pattern until the tumor's presence is no longer detected.…”