Surgical Decompression in Dogs with Thoracolumbar Intervertebral Disc Disease and Loss of Deep Pain Perception: A Retrospective Study of 46 Cases

Laitinen, Outi; Puerto, David A.

doi:10.1186/1751-0147-46-79

Cited by 63 publications

(21 citation statements)

References 12 publications

(24 reference statements)

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“…Findings of the present study suggest that, besides the previously known/described effect of breed on IVDD (10), temperature might also have influenced the occurrence of IVDD in the Lake Geneva canine population from 2007 to 2012. Chondrodystrophic dogs constituted just over 65% of our case population, which correlates well with what was previously reported in different studies (4,(26)(27)(28). The Dachshund, which was formerly found to be responsible for up to 79% of all IVDD cases (29), was the second most common breed in our study after the French Bulldog.…”

Section: Discussionsupporting

confidence: 91%

Colder Ambient Temperatures Influence Acute Onset Canine Intervertebral Disc Extrusion

Barandun

Bult²,

Demierre³

et al. 2020

Front. Vet. Sci.

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Canine intervertebral disc disease is one of the most common neurologic conditions in veterinary medicine but the influence of environmental factors thereon has not been fully investigated. Subjectively, there has been the impression of increased admissions of acute spinal cord injuries due to intervertebral disc extrusion during periods of colder temperatures. In the present retrospective study, the different weather conditions (temperature, precipitation, sunshine, humidity, and atmospheric pressure) during the acute onset of clinical signs and a lag period of 3 days prior to the occurrence of symptoms were analyzed. One-hundred-and-one client owned dogs from the meteorological region of the Lake Geneva were presented to two referral centers during the 6-year (2007-2012) study period. Chondrodystrophic dogs represented 65.3% of our population, with the French Bulldog (19.8%) and Dachshund (17.8%) being the most common breeds. Multivariable logistic regression analysis identified an increased occurrence of intervertebral disc disease during colder temperatures. Our results are congruent with those of human studies which have shown that lower ambient temperatures are associated with more pain and increased risk for muscle injuries. The interplay of endogenous (breed, anatomical characteristics) and exogenous (environmental) factors should be addressed in a larger cohort study.

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Section: Discussionsupporting

confidence: 91%

Colder Ambient Temperatures Influence Acute Onset Canine Intervertebral Disc Extrusion

Barandun

Bult²,

Demierre³

et al. 2020

Front. Vet. Sci.

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“…Consistent with previous studies,11, 12, 13, 14, 15, 41, 42 45.7% of grade 5 dogs became ambulatory within 6 weeks, compared with 100% of grade 3 and 4 dogs. While the regression tree for the OFS outcome measure revealed conflicting effects of total duration of anesthesia in a small subgroup (Fig 1), considering the similar findings in the regression tree analysis for ambulatory status (Fig 3) as well as the final general linear and ridge regression models, the predominant relationship identified in grade 5 dogs was a poorer outcome with increased duration of surgery (Figs 1, 3; Tables 3, 5).…”

Section: Discussionsupporting

confidence: 90%

“…For this analysis, functional grade at presentation as well as the recorded anesthetic variables (premedication drugs used, duration of general anesthesia, duration of surgery, number of disk spaces operated on, total duration of low MABP, total duration of low SBP, total duration of bradycardia, mean temperature, mean ETCO 2 , IV fluid boluses, and glycopyrrolate4 boluses as well as years of surgical training of the surgeon) was included to control for the well‐established effect of initial injury severity on outcome (Table 2). 10, 12, 13, 15 The variables identified by the regression tree analysis were then selected for further multivariable analysis by fitting a linear model for continuous outcome scores (OFS and RI) fit using ordinary least squares, and a logistic regression model fit using maximum likelihood with a ridge penalty for the binary outcome measure (ambulatory status) 38, 39. The reported coefficients are for the final selected models, where selection was performed using stepwise variable selection with the Bayesian information criterion.…”

Section: Methodsmentioning

confidence: 99%

“…While the varying outcome of dogs with different initial severities of thoracolumbar SCI has been well described, the possibility that there are factors associated with surgical and anesthetic procedures that affect outcome has not been investigated 6, 10, 11, 12, 13, 14, 15. It has long been recognized in the experimental setting that perfusion of the spinal cord is highly associated with outcome 16, 17, 18.…”

mentioning

confidence: 99%

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Associations Between Anesthetic Variables and Functional Outcome in Dogs With Thoracolumbar Intervertebral Disk Extrusion Undergoing Decompressive Hemilaminectomy

Fenn

Laber

Williams

et al. 2017

Veterinary Internal Medicne

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BackgroundOutcome of acute experimental spinal cord injury is strongly associated with tissue perfusion and oxygenation. Cardiopulmonary depression could affect outcome in dogs undergoing general anesthesia for surgical treatment of thoracolumbar intervertebral disk extrusion (IVDE).Hypothesis/ObjectivesTo evaluate the effects of general anesthesia on functional outcome in dogs undergoing surgery to treat thoracolumbar IVDE.AnimalsEighty‐four client‐owned dogs with acute thoracolumbar IVDE treated by decompressive hemilaminectomy.MethodsExploratory, retrospective observational study. Medical records were reviewed for clinical presentation and anesthetic monitoring variables, including duration of anesthesia and surgery, hypotension, bradycardia, temperature, and respiratory parameters. Multivariable regression tree analysis was performed to explore associations between anesthetic variables and functional outcome scores after 6 weeks, as well as return to ambulatory status.ResultsEpisodes of bradycardia (69%) and hypotension (57%) were frequent. Across all outcome measures, regression tree analysis highlighted functional grade at presentation as the primary determining factor, and among pain perception negative dogs, there was a possible association between increased duration of surgery and poorer outcome. In dogs with intact pain perception, duration of bradycardia, mean body temperature, and mean end‐tidal carbon dioxide were highlighted.Conclusions and Clinical ImportanceExploratory statistical methods can facilitate hypothesis‐generating studies to inform prospective investigations in veterinary medicine. Although the mechanism is uncertain, increased duration of surgery might be associated with poorer outcome in pain perception negative dogs with thoracolumbar IVDE.

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“…Os cães com DDIV toracolombar grau V submetidos à hemilaminectomia apresentaram índices de recuperação semelhante a outros estudos, que referem a ocorrência de melhora entre 0 e 76% (Brisson 2010). Entretanto, a maioria dos estudos considera o evento "retorno da locomoção" como bom resultado, não citando a ocorrência de outras complicações além de mielomalácia hemorrágica, infecção urinária e opção por eutanásia (Olby et al 2003, Laitinen & Puerto 2005, Jeffery et al 2016.…”

Section: Doença Do Disco Intervertebralunclassified

Complicações observadas em cães e gatos com doenças neurológicas

Santoro

Árias

2018

Pesq. Vet. Bras.

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RESUMO.-Cães e gatos com problemas neurológicos estão sujeitos a várias sequelas e complicações, em decorrência das deficiências motoras, sensoriais e viscerais. Algumas complicações estão relacionadas a maior mortalidade, principalmente aquelas relacionadas ao trauma vertebromedular. O objetivo do presente estudo foi avaliar nessas espécies a frequência do aparecimento de complicações, a epidemiologia, localização da lesão e etiologia, avaliando ainda a evolução e o tempo de sobrevida. Foram acompanhados 100 cães e gatos com doenças neurológicas trazidos para atendimento no Serviço de Neurologia do Hospital Veterinário da Universidade Estadual de Londrina. Observou-se que 91% dos animais desenvolveram complicações, sendo que as mais frequentes foram atrofia muscular (n=32), retenção urinária (n=24), incontinência urinária (n=24), incontinência fecal (n=17) e feridas de decúbito (n=16). O principal local de lesão associado ao aparecimento das complicações foi medula espinhal (91,3%) e a principal etiologia foi o trauma vertebromedular (37,3%). O tempo mediano e médio de vida estimado foram, respectivamente, dois e sete meses sendo que as principais causas de morte ou eutanásia estavam relacionadas ao trauma vertebromedular, trauma cranioencefálico ou doença inflamatória/infecciosa. O tempo de vida estimado foi menor para animais mais velhos e mais pesados. Embora o índice de sobrevivência dos animais com complicações tenha sido alto, muitos permaneceram com sequelas, indicando que a sobrevivência não significou capacidade funcional normal. Cães e gatos com problemas neurológicos requerem alto grau de atenção do veterinário e de seus tutores, sendo ABSTRACT.-Santoro M.B. & Bahr Arias M.V. 2018. [Complications observed in dogs and cats with neurological diseases]. Complicações observadas em cães e gatos com doenças neurológicas. Pesquisa Veterinária Brasileira 38(6):1159-1171. Dogs and cats with neurological diseases can show several sequelae and complications as a result of motor, sensory and visceral deficiencies. Some complications are an important cause of mortality, mainly complications related to spinal cord injury. The aim of this study was to evaluate in 100 dogs and cats brought to the Neurology Service of Veterinary Hospital from Universidade Estadual de Londrina the frequency of complications, epidemiology, lesion localization and etiology, still assessing the evolution and survival time.It was observed that 91% of the animals developed complications. The most frequent were muscular atrophy (n=32), urinary retention (n=24), urinary incontinence (n=24), fecal incontinence (n=17) and pressure sores (n=16). The main site of injury associated with the onset of complications was spinal cord (91%) and the main cause was the spinal cord trauma (37.3%). The median survival time of animals with complications was two months and the mean was seven months. The main causes of death or euthanasia were related do spinal cord trauma, traumatic brain injury or inflammatory/infectious disease. The estimated lifetime was l...

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Surgical Decompression in Dogs with Thoracolumbar Intervertebral Disc Disease and Loss of Deep Pain Perception: A Retrospective Study of 46 Cases

Cited by 63 publications

References 12 publications

Colder Ambient Temperatures Influence Acute Onset Canine Intervertebral Disc Extrusion

Colder Ambient Temperatures Influence Acute Onset Canine Intervertebral Disc Extrusion

Associations Between Anesthetic Variables and Functional Outcome in Dogs With Thoracolumbar Intervertebral Disk Extrusion Undergoing Decompressive Hemilaminectomy

Complicações observadas em cães e gatos com doenças neurológicas

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