Surgical Considerations in Inner Ear Gene Therapy from Human Temporal Bone Anatomy
Alyssa Brown,
MengYu Zhu,
Alireza Rohani
et al.
Abstract:Objective(s)Recently directed methods of inner ear drug delivery underscore the necessity for understanding critical anatomical dimensions. This study examines anatomical measurements of the human middle and inner ear relevant for inner ear drug delivery studied with three different imaging modalities.MethodsPost‐mortem human temporal bones were analyzed using human temporal bone histopathology (N = 24), micro computerized tomography (μCT; N = 4), and synchrotron radiation phase‐contrast imaging (SR‐PCI; N = 7… Show more
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