Surgical aspects of malaria

Gibney, Eugene J.

doi:10.1002/bjs.1800770905

Cited by 22 publications

(8 citation statements)

References 55 publications

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“…One of the most common presenting conditions requiring surgery for patients with malaria is tropical splenomegaly with splenic rupture due to traumatic or non-traumatic causes. Plasmodium vivax and ovale remain dormant in the liver for long durations, and the stress associated with anesthesia and surgery may induce relapse [15][16][17]. Complete general and system-wise physical examination, along with preoperative laboratory investigations including a complete blood count, blood type with cross-match, electrolytes, coagulation profile, renal and hepatics function tests, blood glucose and lactate, chest X-ray and electrocardiography should be performed.…”

Section: Discussionmentioning

confidence: 99%

Anesthetic Implications of Malarial Infection in a Child

et al. 2019

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Malaria is a life-threatening mosquito-borne parasitic disease, with a wide clinical spectrum and multisystem involvement. It is associated with high rates of mortality and morbidity worldwide, particularly in Africa and Southeast Asia. Cases are now being reported in developed countries resulting from global and international travel. Given the varied presentation and multisystem involvement, patients with malaria may present for surgery, thereby necessitating anesthetic care. We present a 4-year-old child from Burkina Faso, Africa, with a known diagnosis of Plasmodium falciparum malaria, who presented for anesthetic care for a magnetic resonance imaging of the lumbar spine, requiring general anesthesia. The etiology and presentation of malaria are discussed and its end-organ involvement is reviewed with emphasis on the anesthetic implications of the disease.

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Section: Discussionmentioning

confidence: 99%

Anesthetic Implications of Malarial Infection in a Child

et al. 2019

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“…The stress of major surgery and anesthesia, however, may induce relapse of Plasmodium vivax and ovale malaria as these types can remain dormant in the liver for many years. 33 Recurrence has also been described with falciparum malaria. 34 In patients with a perioperative diagnosis of malaria infection, regular postoperative blood smears assessing for parasitemia should be performed every eight to 12 hr.…”

Section: Plasmodium Life Cyclementioning

confidence: 98%

Perioperative considerations of the patient with malaria

Soltanifar

Carvalho

Sultan

2014

Can J Anesth/J Can Anesth

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Purpose Malaria is a life-threatening infectious disease caused by the Plasmodium parasite. Increased global travel has resulted in an escalation in the number of imported cases seen in developed countries. Patients with malaria may present for surgery in both endemic and nonendemic countries. This article reviews the perioperative considerations when managing patients with malaria. Source A literature review of anesthesia, perioperative care, and malaria-related articles was performed using the MEDLINE Ò , EMBASE TM , and Web of Science databases to identify relevant articles published in English during . Of the 303 articles matching the search criteria, 265 were excluded based on title and abstract. Eleven of the remaining 38 articles were relevant to anesthesia/perioperative care, and 27 articles were identified as having direct relevance to critical care medicine. Principal findings The majority of imported malaria cases are caused by the falciparum species, which is associated with the greatest degree of morbidity and mortality. Various organ systems may be impacted as a consequence of changes in the structure and function of parasitized erythrocytes. Preoperative assessment should focus on establishing the species of malaria, the severity of disease, assessing the degree of end-organ impairment, and initiating treatment of malaria prior to surgery. Intravenous artesunate is the treatment of choice for severe falciparum malaria. Quinine is a second-line agent but has a narrow therapeutic index and particularly hazardous side effects. Intraoperatively, attention should focus on fluid management, dynamics of cerebral blood flow, and avoidance of hypoglycemia. Postoperative care of severe cases should ideally take place in a critical care unit as there may be ongoing requirements for multi-organ support, including renal replacement therapy, ventilation, and/or inotropic support. The safety of neuraxial anesthesia has not been well studied in the setting of malaria. Conclusions Malaria remains one of the most devastating infectious diseases worldwide. Multiple organ systems can be impacted as a consequence of changes in structure and function of parasitized erythrocytes. Safe perioperative management requires a sound knowledge of all these potential system effects. RésuméObjectif Le paludisme est une maladie infectieuse possiblement fatale due au parasite Plasmodium. La multiplication des voyages à travers le monde a entraîné un accroissement du nombre de cas importés observés dans les pays développés. Les patients atteints de paludisme peuvent nécessiter une chirurgie, aussi bien dans les pays où la maladie est endémique que dans les autres. Cet article passe en revue les considérations périopératoires lors de la prise en charge de patients atteints de paludisme. Source Une revue de la littérature à la recherche d'articles d'anesthésie, de soins périopératoires et en Author contributions Daniel Soltanifar, Brendan Carvalho, and Pervez Sultan all made substantial contributions to the literature review, ...

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“…Cette intervention expose notamment les patients à un risque d'accès palustre au décours de la chirurgie [11,68].…”

Section: Traitementunclassified