Surgical Anterior Ventricular Endocardial Restoration (SAVER) for Dilated Ischemic Cardiomyoathy

Athanasuleas, Constantine L.; Stanley, Alfred W.H.; Buckberg, Gerald D.; Dor, Vincent; Donato, Marisa Di; Siler, William

doi:10.1053/stcs.2001.30372

Cited by 68 publications

(39 citation statements)

References 23 publications

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“…Thus . These findings reinforce the idea that achieving smaller left ventricular cavities with a greater exclusion of akinetic areas, might contribute to an improved evolution of operated patients over the long term [5].…”

Section: Commentssupporting

confidence: 77%

“…The appearance of new concepts for the surgical reconstruction of the left ventricle shows that elimination of akinetic areas, as well as diskinetic areas of the left ventricle could potentially give a better restoration of the form and function (study of Saver) [5].…”

Section: Commentsmentioning

confidence: 99%

“…Recent studies demonstrated that survival of patients evolving with heart failure, as well as survival after reconstruction of the LV, are related to the size of the left ventricular cavity, that is, the final systolic and diastolic volumes [3][4][5]. However, not using patches during LV reconstruction may contribute to an additional reduction of the left ventricular cavity.…”

Section: Introductionmentioning

confidence: 99%

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Reconstrução fisiológica do ventrículo esquerdo: o conceito de máxima redução ventricular e mínima resposta inflamatória

Gomes¹,

Jaramillo²,

Asanuma³

et al. 2004

Rev Bras Cir Cardiovasc

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Section: Commentssupporting

confidence: 77%

Section: Commentsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

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Reconstrução fisiológica do ventrículo esquerdo: o conceito de máxima redução ventricular e mínima resposta inflamatória

Gomes¹,

Jaramillo²,

Asanuma³

et al. 2004

Rev Bras Cir Cardiovasc

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“…Surgical treatment of severe heart failure focuses on regaining a sufficient pumping function primarily of the left ventricle, which results from a physiological volume and the natural geometry of the left ventricle [48]. Since the 1980s, therefore, myocardial reconstruction according to Dor has been applied [6,7] whereby, the damaged, non-functioning heart tissue is resected and reinforced by synthetic grafts such as Dacron.…”

Section: Congestive Heart Failurementioning

confidence: 99%

Cardiovascular Applications of Magnesium Alloys

Schilling¹,

Bauer²,

LaLonde³

et al. 2017

Magnesium Alloys

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Therapy in cardiovascular medicine often relies on implantation of prosthetic materials or application of stents. The diseases of many cardiovascular structures require their complete and immediate repair by utilising prosthetic materials. The ideal cardiovascular prosthesis involves good functional properties, capability of regeneration and does not activate the host's immune system. Ideally, the graft can be applied for a temporary use and degrades after a predefined period according to controlled degradation kinetics. Only biological grafts would provide this spectrum of properties by today's level of knowledge. However, biological prostheses exhibit some relevant drawbacks as well, such as insufficient mechanical stability or restricted availability. Implants or supporting structures of magnesium alloys would bridge this gap and would either provide a substrate for innovative and temporary grafts or would-as supporting structures-transiently add some missing properties to regenerative biological prostheses. This chapter reviews the different fields of cardiovascular therapeutic applications of magnesium alloys. The required properties of magnesium alloys and their preparation, fabrication and testing will be discussed under the specific cardiovascular perspective.

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“…SVR implies making an incision into the scarred and dilated myocardium, the placement of a suture inside the LV to exclude the scarred segment and the repair of the abnormal area with an endocardial patch. Athanasuleas et al (51), as well as other authors, have demonstrated that SVR benefits patients with ischemic cardiomyopathy and an anterior scar by improving LV volumes, LVEF and the New York Heart Association functional class (14,(50)(51)(52)(53). The Reconstructive Endoventricular Surgery returning Torsion Original Radius Elliptical shape to the left ventricle (RESTORE) group (51) have also reported that in selected patients, SVR with CABG alone is associated with a better prognosis than is generally associated with LV dysfunction and heart failure, and with an acceptably low operative mortality (7.7%), particularly when ventricular end-systolic dilation is not markedly increased (5.5%).…”

Section: The Role Of Svrmentioning

confidence: 99%