Surgical and oncologic outcomes following laparoscopic versus open liver resection for hepatocellular carcinoma: A meta‐analysis

Abstract

On currently available evidence, laparoscopic resection appears not to affect oncologic outcomes and increase tumor recurrence. It also offers less blood loss, decreased rate of intraoperative transfusion and shorter lengths of hospital stay. Laparoscopic resection is a safe and feasible choice for selected patients with HCC.

Current management of hepatocellular carcinoma: An Eastern perspective

“…Although this study showed a nonsignificant trend toward better antitumoral effects with DEB-TACE, a case-control study conducted in Korea reported a Recently, laparoscopic liver resection has been implemented for the treatment of HCC. This is a minimally invasive surgery, so postoperative morbidity and duration of hospitalization are reduced with no changes in surgical margin status, tumor recurrence, and overall survival [32] . This technique is successfully being applied for the resection of large tumors between 5 and 10 cm and lesions at difficult-toapproach locations [33][34][35] as well as intra-abdominal metastatic HCCs in Asian countries [36] .…”

Bleeding control during laparoscopic liver resection: a review of literature

“…Furthermore, these were found to be lower after LLR in 40 and 11 studies, respectively. Twelve meta-analyses and one Cochrane report were also analyzed [35][36][37][38][39][40][41][42][43][44][45][46][47] and consistent results included reduced blood loss and transfusions requirements when studied. This clearly shows that, in selected patients LLR when compared with open surgery is associated with reduced blood loss and subsequent transfusion rates.…”

Recent advances in surgical treatment of hepatocellular carcinoma

“…The main concern about using laparoscopy to treat malignancies is the risk of inadequate tumor resection. In a number of studies (76)(77)(78)(79) comparing laparoscopic and open liver resection for treatment of HCC, there was no significant difference in recurrence-free or overall survival, suggesting that laparoscopic surgery does not compromise oncological principles.…”

“…A meta-analysis indicated that laparoscopic resection consistently yields favorable results in terms of the duration of hospitalization (77)(78)(79), consequently reducing the overall morbidity rate and incidence of intractable ascites. The main concern about using laparoscopy to treat malignancies is the risk of inadequate tumor resection.…”