Surgical and ablative therapies for the management of adrenal ‘oligometastases’ – A systematic review

Gunjur, Ashray; Duong, Cuong; Ball, David; Siva, Shankar

doi:10.1016/j.ctrv.2014.04.001

Cited by 76 publications

(79 citation statements)

References 60 publications

Supporting

Mentioning

Contrasting

Unclassified

Order By: Relevance

“…15 Recently adrenal gland metastases of 46%, representing a total of 655 patients. 16 Other recently emerged treatment modalities include Radiofrequency Ablation (RFA), Microwave Ablation (MWA) and Stereotactic Body Radiation Therapy (SBRT). 17 Limited data are available on the Percutaneous Catheter Ablation Technique due to a limited number of patients.…”

Section: Introductionmentioning

confidence: 99%

“…The most common histology treated with this modality is renal cell carcinoma, where reported toxicity included hypertensive crisis and retroperitoneal haematoma. 16 SBRT refers to the administration of large doses of highly conformal radiation with steep dose gradients towards the surrounding normal tissue over a limited number of fractions. SBRT usually provides much higher Biologically Equivalent Doses (BED) compared with conventional treatments and has been used as a non-invasive alternative to the gold standard of surgery in selected patients.…”

Section: Introductionmentioning

confidence: 99%

See 1 more Smart Citation

SBRT: A viable option for treating adrenal gland metastases

Ippolito

D’Angelillo

Fiore

et al. 2015

Reports of Practical Oncology & Radiotherapy

View full text Add to dashboard Cite

a b s t r a c tThe management strategy of adrenal metastases depends on different clinical situations.Adrenal metastasectomy in selected patients with isolated adrenal metastases is considered the treatment of choice, showing prolonged survival compared to chemotherapy alone.More recently, Stereotactic Body Radiation Therapy (SBRT) has emerged as an alternative local ablative treatment modality although limited data are available on the use of SBRT in treating adrenal gland metastases. Preliminary results are, however, encouraging, especially in selected patients with oligometastatic disease. We herewith review and discuss the potential role of SBRT as a local ablative treatment modality for adrenal metastases.

show abstract

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

SBRT: A viable option for treating adrenal gland metastases

Ippolito

D’Angelillo

Fiore

et al. 2015

Reports of Practical Oncology & Radiotherapy

View full text Add to dashboard Cite

show abstract

“…There are multiple single cohort prospective studies and retrospective reviews of using SABR for the treatment of lung metastases, showing 2-year local control rates and overall survival rates of 90 -100% and 50 -70%, respectively [5,6,8]. Other body sites (including lung, liver, adrenal and lymph nodes) have also been treated with SABR, with local control rates ranging from 67 -95%, and 2-3-year survival rates in the range of 30 -64% [1,9].…”

Section: Introductionmentioning

confidence: 99%

Stereotactic Ablative Body Radiotherapy for the Treatment of Spinal Oligometastases

et al. 2017

View full text Add to dashboard Cite

After the embargo period via non-commercial hosting platforms such as their institutional repository  via commercial sites with which Elsevier has an agreement In all cases accepted manuscripts should: link to the formal publication via its DOI  bear a CC-BY-NC-ND license -this is easy to do, click here to find out how  if aggregated with other manuscripts, for example in a repository or other site, be shared in alignment with our hosting policy  not be added to or enhanced in any way to appear more like, or to substitute for, the published journal article This cohort warrants further investigation in clinical trials of SABR.

show abstract

“…These bulks can be treated with open and laparoscopic surrenalectomy in a curative way. It was reported in studies that overall survival was longer in resection of clinically isolated adrenal metastases when compared with nonsurgical therapy (including RFA, external beam radiotherapy, arterial embolization, radioembolization, chemical ablation, and cryoablation) [1,2,5,7]. Lo et al, found one-year survival as 73% and two-year survival as 40% in their study conducted on 52 patients having curative resection for solitary adrenal metastasis [3].…”

mentioning

confidence: 99%

“…Tanvetyanon et al, demonstrated 5-year survival rates of 25% following resection of isolated synchronous adrenal metastases and reported 26% after resection of metachronous adrenal metastases in their study conducted on NSCLC patients developing solitary adrenal metastasis [4]. Conducted studies revealed that the rate of complication was 9-20% in patients having adrenalectomy for solitary adrenal metastasis [2][3][4]7].In recent years, the use of radiotherapy, which is a treatment modality as effective as surgical resection, has become prevalent for the management of oligometastases. Today, three different modalities have been tested in the radiotherapy treatment of adrenal gland metastases.…”

mentioning

confidence: 99%

Adrenal insufficiency in Bilateral Adrenal Metastasis implemented SBRT

Cihan¹

2018

J Radiol Oncol

View full text Add to dashboard Cite

Today, there is a considerable increase in localizing adrenal bulks with the bringing radiologic diagnosis methods having high technology into use and improvement in diagnostic tests. Adrenal glands are vital tissues for the organism due to the hormones they secrete. Death is a natural result in the absence of adrenal cortex. Adrenal bulks can be seen with different clinical, laboratory and radiological data. These bulks are often benign and rarely malign. They can be functional or non-functional. Major treatment methods used fort he treatment of adrenal gland primary tumors or metastases are surgery, arterial embolisation, chemical ablation, radiofrequency ablation and radiotherapy [1][2][3][4].Adrenal glands are one of the metastatic ields. In wide autopsy series, adrenal metastasis has been determined between the rates of 13-17% [5]. While unilateral metastasis is common, bilateral metastasis' rate of incidence is between 4-20%. It has been stated that lung (35%), gastric (14%), esophageal (12%) and hepatobiliary (10%) primary carcinomas adrenal metastasis are prevalent most frequently [2]. Curative treatments are tested on patients having cancer with oligo metastasis limited with adrenal gland and primary source is under control because of the expectation of longterm survival, and the surgery is the irst choice. These bulks can be treated with open and laparoscopic surrenalectomy in a curative way. It was reported in studies that overall survival was longer in resection of clinically isolated adrenal metastases when compared with nonsurgical therapy (including RFA, external beam radiotherapy, arterial embolization, radioembolization, chemical ablation, and cryoablation) [1,2,5,7]. Lo et al., found one-year survival as 73% and two-year survival as 40% in their study conducted on 52 patients having curative resection for solitary adrenal metastasis [3]. Tanvetyanon et al., demonstrated 5-year survival rates of 25% following resection of isolated synchronous adrenal metastases and reported 26% after resection of metachronous adrenal metastases in their study conducted on NSCLC patients developing solitary adrenal metastasis [4]. Conducted studies revealed that the rate of complication was 9-20% in patients having adrenalectomy for solitary adrenal metastasis [2][3][4]7].In recent years, the use of radiotherapy, which is a treatment modality as effective as surgical resection, has become prevalent for the management of oligometastases. Today, three different modalities have been tested in the radiotherapy treatment of adrenal gland metastases. In the irst one, total 50 Gy treatment dose with 3D-CRT as daily 2 Gy fraction dose is given [8]. The second one is IMRT implementations for adrenal gland metastases but it isn't thought as suitable according to Practice Guidelines for Neuroendocrine Tumors published by NCCN in 2010. The third radiotherapy modality is stereotactic body radiotherapy (SBRT). SBRT implementations have started to be preferred today since they are completed in a few fractions in addition to tha...

show abstract

Surgical and ablative therapies for the management of adrenal ‘oligometastases’ – A systematic review

Cited by 76 publications

References 60 publications

SBRT: A viable option for treating adrenal gland metastases

SBRT: A viable option for treating adrenal gland metastases

Stereotactic Ablative Body Radiotherapy for the Treatment of Spinal Oligometastases

Adrenal insufficiency in Bilateral Adrenal Metastasis implemented SBRT

Contact Info

Product

Resources

About