Surgical anatomy of the pudendal nerve and its branches in South Africans

Walt, S Van der; Oettlé, Anna Catherina; Patel, Hitendra

doi:10.1038/ijir.2015.10

Cited by 8 publications

(4 citation statements)

References 24 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…However, the mechanism by which ES promotes peripheral nerve regeneration remains unclear. The pudendal nerve, an important peripheral nerve, dominates all striated muscles of the pelvic floor, including the urethra and anal sphincter, and it plays an extremely important role in the maintenance of pelvic floor function 22,28 . Pudendal nerve injury is an important factor in the occurrence of SUI, and the degree of nerve injury determines the recovery of SUI.…”

Section: Discussionmentioning

confidence: 99%

Electrical stimulation enhances neuronal cell activity mediated by Schwann cell derived exosomes

Liu

et al. 2019

Sci Rep

View full text Add to dashboard Cite

Electrical stimulation (ES) therapy has good effects in patients with nervous system injury-related diseases. ES promotes nerve cell regeneration and stimulates Schwann cells to express neurotrophic factors. The incidence of stress urinary incontinence (SUI) among elderly people is increasing. Some studies suggest that damage to the pudendal nerve is closely related to the pathogenesis of SUI. It has also been found that pelvic ES can reduce SUI symptoms in a rat model of SUI caused by pudendal nerve injury. Clinically, pelvic floor electrical stimulation is effective in patients with mild to moderate SUI. These studies indicate that ES may ameliorate damage to the pudendal nerve and thus achieve the goal of SUI treatment, although the mechanism of action of this treatment remains unclear. Therefore, the purpose of the present study was to clarify the relationships among ES, neural cells and Schwann cells at the cellular level. We applied ES to nerve cells at 100 mV/mm or 200 mV/mm for 0, 0.5, 1, or 2 h to investigate changes in nerve cell activity. We then co-cultured the nerve cells with Schwann cells to explore the influence of single-culture and co-culture conditions on the nerve cells. Compared to non-ES, ES of the nerve cells increased their activity. Compared to those in single culture, co-cultured nerve cells exhibited an additional increase in activity. We also found that Schwann cell derived exosomes could promote the activity of nerve cells, with glutamate and calcium ions playing a potential role in this process. These results suggest that the mutual regulation of neural cells and Schwann cells plays an important role in the process by which ES ameliorates neurological function, which may provide a basis for subsequent studies.

show abstract

Section: Discussionmentioning

confidence: 99%

Electrical stimulation enhances neuronal cell activity mediated by Schwann cell derived exosomes

Liu

et al. 2019

Sci Rep

View full text Add to dashboard Cite

show abstract

“…The sample size did not allow a statistical comparison, necessitating the use of descriptive statistics. Lack of diversity between race and ethnicity may limit the generalizability of pudendal nerve anatomy and surgical treatment outcomes in other populations (van der Walt, Oettle, & Patel, 2015). Patients that presented for consultation had tried all other treatments without relief.…”

Section: Discussionmentioning

confidence: 99%

Persistent genital arousal disorder: Treatment by neurolysis of dorsal branch of pudendal nerve

Klifto

Dellon

2019

Microsurgery

View full text Add to dashboard Cite

Background Persistent genital arousal disorder (PGAD) is a woman's perception that she is in a state of sexual arousal, without the ability of arousal to be satisfied by orgasm. It is the hypothesis of this study that PGAD results from a minimal degree of nerve compression of the dorsal branch of the pudendal nerve. If this is true, PGAD could be treated by neurolysis of the dorsal branch of the pudendal nerve. Methods A retrospective chart review from 2010 through 2018, of those women having neurolysis of the dorsal branch of the pudendal nerve for PGAD. The main outcome measures were the pre‐operative and post‐operative changes in clitoral symptoms (arousal, numbness, pain). Results Eight women included in this study were followed more than 26 weeks since surgery (mean = 65, range = 26–144 weeks). Seven of these women had the surgery bilaterally, and each of these had an excellent result, meaning elimination of the arousal symptoms, and the ability to resume normal sexual intercourse. The patient with unilateral decompression of the dorsal branch of the pudendal nerve was the only patient who had some, versus complete improvement in arousal symptoms. Of the seven women that had pain, six had complete relief and one had partial relief. No major surgical complications were observed. Conclusion The relief of arousal symptoms by neurolysis of the dorsal nerve to the clitoris supports the hypothesis that PGAD is due to a minimal degree of compression of the dorsal branch of the pudendal nerve.

show abstract

“…Later, it re-enters the pelvis through the lesser sciatic foramen, dorsal to the sacrospinous ligament and ventral to the sacrotuberous ligament. 8,35,41,44,[54][55][56][57] It is in the interligamentous portion of its course where compressive nerve pathologies may be frequently found (see Figs. 3 and 4).…”

Section: Pudendal Nerve Anatomymentioning

confidence: 99%

“…1,49,59 At the gluteal level, the internal pudendal artery was found lateral to the nerves in 60% of cases, medial in 35% and on either side of the nerves (double), and slightly lateral and ventral to them, in 5% of cases. 2,53,57,60,61 Technique Pudendal nerve blocks may be performed through two approaches: anterior/perineal 1,2,7,54 or posterior/ transgluteal. 2,49,56,59,[62][63][64][65] The perineal approach is used for distal entrapments or for anaesthetic/analgesic purposes in gynaecological, urological or colorectal surgery.…”

Section: Pudendal Nerve Anatomymentioning

confidence: 99%

Regional anesthesia guided by ultrasound in the pudendal nerve territory☆

Rojas-Gómez

Blanco-Dávila

Roa

et al. 2017

Colombian Journal of Anesthesiology

View full text Add to dashboard Cite

Introduction: Pudendal nerve blocks have a wide range of clinical applications for the management of acute post-operative pain in urologic, gynecological surgery, in coloproctology, as well as in pain medicine for differential diagnosis, and for the management of pudendal neuropathies. However, despite its benefits it is infrequently used.Objective: To perform a detailed description of the most recent ultrasound-guided techniques with the aim of encouraging safe and reproducible learning. Materials and methods:We have performed a broad, non-systematic review of the literature through Medline, Embase and Science Direct between 1985 and 2016, to evaluate the most relevant articles, using the following key words: pudendal nerve anatomy, pudendal nerve, pudendal nerve blocks, pudendal nerve ultrasound, pudendal neuralgia, nerve entrapment, chronic pain, Alcock canal, and pelvic pain. The search was limited to articles published in Spanish, English and French.Results: Recent descriptions were found of a large number of anatomic variants, which are described in detail and shown in graphic documents in order to facilitate the sonoanatomic correlation of nerve location as a guide for the performance of the pudendal nerve block through the different approaches.

show abstract

Surgical anatomy of the pudendal nerve and its branches in South Africans

Cited by 8 publications

References 24 publications

Electrical stimulation enhances neuronal cell activity mediated by Schwann cell derived exosomes

Electrical stimulation enhances neuronal cell activity mediated by Schwann cell derived exosomes

Persistent genital arousal disorder: Treatment by neurolysis of dorsal branch of pudendal nerve

Regional anesthesia guided by ultrasound in the pudendal nerve territory☆

Contact Info

Product

Resources

About