Surgery versus Radioiodine Therapy as Definitive Management for Graves' Disease: The Role of Patient Preference

Abstract

One-third of all patients electing surgery as definitive management do so in the absence of a specific indication. Overall, there is a high level of satisfaction with the decision for surgery as definitive management of Graves' disease.

Extremely high doses of radioiodine required for treatment of Graves' hyperthyroidism: a case report

“…Therefore for patients with larger goiter and higher 99m Tc-pertechnetate uptakes, a calculated dose based on size and uptake is perhaps a better decision [12]. Surgical treatment (partial thyroidectomy) is also a reasonable option in such cases, as it propitiates prompt relief of symptoms related to compression of the esophagus and/or trachea [13]. …”

Thyroidectomy for Graves' Disease: A Feasibility Study of the Robotic Transaxillary Approach

“…The complication rates are usually higher for patients with GD and thyroiditis due to the increased vascularity and inflammation of the gland. Studies have reported complication rates of 6-20% for transient hypocalcaemia, 0-3% for permanent hypocalcaemia, 0-9.2% for transient RLN injury, and 0-2.4% for permanent RLN injury [12,20,21,22,23,24]. In our study, patients with robotic surgery had a complication rate of 8.3% for temporary hypocalcaemia, but there were no cases of permanent hypocalcaemia or RLN injury.…”

Treatment of Hyperthyroidism in Patients with Graves’ Orbitopathy

“…In recurrent hyperthyroidism, thyroidectomy is a valid alternative to RAI according to patient choice [ 29 ]. Thyroid surgery should be performed by skilled and experienced surgeons to minimize the risk of related complications, namely, hypoparathyroidism and laryngeal nerve paralysis [ 30 ].…”