Surgery versus Chemonucleolysis for Herniated Lumbar Discs

EJESÄR, ARVID; Nachemson, Alf; Herberts, Peter; Lysell, E; Andersson, Gunnar; Irstam, Lars; PETERSON, LARS-ERIK

doi:10.1097/00003086-198304000-00035

Cited by 96 publications

(96 citation statements)

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“…This cartilage mass might be walled off from normal tissue by lamellar bone or may undergo calcification or may proliferate as an intraosseous chondroma. This pathophysiology may play a role in similar conditions like fibrous dysplasia [9].…”

Section: Introductionmentioning

confidence: 88%

“…The symptoms commonly associated with this lesion are slow growing swelling, pathological fracture (43%) and pain (65.7%) following trivial trauma [9].…”

Section: Introductionmentioning

confidence: 99%

“…The Kirshner cy with or without specs of calcification in the diaphysis or metaphysis of the hand. As these tumors grow, endosteal scalloping, cortical thinning and remodeling of the bone become evident [9]. Magnetic resonance imaging (MRI) and Computed Tomography scans (CT) have limited role in diagnosing enchondromas.…”

Section: Introductionmentioning

confidence: 99%

“…Hence recurrence of these lesions is usually diagnosed very late. The exact rate of recurrence of these tumors is difficult to gauge due to the recurrent lesions being asymptomatic [9]. Sassoon et al and Gaulke et al reported a recurrence rate of 7 and 14.3% respectively [7,9].…”

Section: Introductionmentioning

confidence: 99%

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A rare case of recurrent enchondroma of the thumb involving the first metacarpophalangeal joint- an unusual disease pattern

Mysore¹,

Murthy²,

Nekkanti³

et al. 2018

Hand Microsurg

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Enchondromas are common benign lesions of the hand. Recurrent lesions, however, may behave notoriously. A potential malignant transformation should be kept in mind while treating such tumors. We report a case of recurrent enchondroma of the first metacarpal of the right hand in a 37-year-old lady. A 37-year-old female patient who presented to us with a recurrent swelling of the thumb. She was surgically treated for the swelling five years back. The swelling recurred four months after surgery and had grown to the current size. We successfully managed the recurrent enchondroma by en bloc excision, bone grafting, and Kirschner wires to stabilize it. Recurrent enchondromas are to be approached cautiously. They may pose a malignant threat. The reasons for recurrence are to be investigated thoroughly to avoid a re-recurrence. Successful treatment of these lesions is dependent on the complete removal of the tumor bed followed by stabilization.

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Section: Introductionmentioning

confidence: 88%

“…The symptoms commonly associated with this lesion are slow growing swelling, pathological fracture (43%) and pain (65.7%) following trivial trauma [9].…”

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

A rare case of recurrent enchondroma of the thumb involving the first metacarpophalangeal joint- an unusual disease pattern

Mysore¹,

Murthy²,

Nekkanti³

et al. 2018

Hand Microsurg

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“…2 The lesions consist of a bony mass, often in the form of a stalk, produced by progressive endochondral ossification of a growing cartilaginous cap. 3 Most lesions are found during the period of rapid skeletal growth and their growth usually ceases when skeletal maturity is reached.…”

Section: Introductionmentioning

confidence: 99%

Solitary osteochondroma of scapula: A case report

et al. 2017

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Osteochondromas are the most common benign tumours of bone. They are most commonly seen in the metaphyseal regions of long bones (femur, tibia, humerus). The scapula is rarely involved, and very few cases of solitary osteochondroma of scapula have been reported in literature. We present the case of a 17 year old male who presented with pain and limited range of motion of his right shoulder. CT scan revealed an osteochondroma on the dorsomedial surface of the right scapula extending into the ventral surface. Surgical excision was done and histopathological study showed osteochondroma of the scapula.

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Correlation between clinicopathological features and karyotype in 100 cartilaginous and chordoid tumours. A report from the Chromosomes and Morphology (CHAMP) Collaborative Study Group

Tallini

Dorfman

Brys

et al. 2001

The Journal of Pathology

133

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The evaluation of chondroid lesions requires full integration of clinical, radiographic, and pathological data; tumour typing is often a challenge for the diagnostic pathologist. Although a variety of chromosomal abnormalities have been documented in chondroid lesions, the potential usefulness of cytogenetic analysis remains unclear. This study has critically reviewed and analysed 117 karyotyped samples from 100 patients with cartilaginous and chordoid tumours. Cases were selected based on successful chromosomal analysis and adequacy of clinical, radiographic, and pathological information. To ensure objective evaluation, the cytogenetic results were correlated in a double-blind setting with consensus diagnoses independently determined on each case, after complete review of the histological, radiographic, and clinical findings. Karyotypic aberrations were identified in 41/92 cartilaginous tumours (5/11 osteochondromas, 2/3 chondromyxoid fibromas, 0/4 chondroblastomas, 11/29 chondromas, 0/3 chondroid tumours of undetermined malignant potential, 22/40 chondrosarcomas and 1/2 miscellaneous cartilaginous lesions) and 5/8 chordomas. Complex karyotypic changes were a feature of malignant tumours (chondrosarcoma and chordoma) and of chondrosarcoma among cartilaginous tumours, where they correlated with high tumour grade. Among primary well-differentiated cartilaginous lesions of bone, the finding of an abnormal karyotype was consistently associated with a grade 1 chondrosarcoma diagnosis. Among karyotypically abnormal cartilaginous tumours, loss of distal 8q was associated with osteochondroma, +5 with synovial chondroma/chondromatosis and parosteal or soft tissue chondroma, alterations of chromosome arm 6q with chondromyxoid fibroma, +7 with bone chondrosarcoma, and 17p1 alterations with grade 3 chondrosarcoma. Alterations involving 12q13 characterized synovial chondroma/chondromatosis in the chondroma group and myxoid chondrosarcoma of bone in the chondrosarcoma group. In conclusion, cytogenetic abnormalities in chondroid lesions are common and are not randomly distributed. They are associated with malignancy/tumour grade as well as with specific diagnoses in many cases, and can therefore be of potential value for tumour typing.

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Surgery versus Chemonucleolysis for Herniated Lumbar Discs

Cited by 96 publications

References 0 publications

A rare case of recurrent enchondroma of the thumb involving the first metacarpophalangeal joint- an unusual disease pattern

A rare case of recurrent enchondroma of the thumb involving the first metacarpophalangeal joint- an unusual disease pattern

Solitary osteochondroma of scapula: A case report

Correlation between clinicopathological features and karyotype in 100 cartilaginous and chordoid tumours. A report from the Chromosomes and Morphology (CHAMP) Collaborative Study Group

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