Surgery of thyroid cancer in children and adolescents

Segal, Karl; Shvero, Jacob; Stern, Yoram; Mechlis, Sarah; Feinmesser, Raphael

doi:10.1002/(sici)1097-0347(199807)20:4<293::aid-hed2>3.0.co;2-u

Cited by 45 publications

(41 citation statements)

References 14 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…Radioiodine ablation with 30-150 mCi of 131 I to destroy any remaining functional thyroid tissue 4 weeks after surgery have been recommended, especially in children under 16 years [15]. Patients require regular follow up and their thyroglobulin levels are monitored, in addition when necessary a diagnostic 131 I whole body scanning is performed annually [6]. Our patient was sent to radioactive iodine treatment and is still under clinical follow up.…”

Section: Discussionmentioning

confidence: 99%

Papillary thyroid carcinoma in a 3-year-old child: Case report

Alkan

Seven

Sakalli

et al. 2008

International Journal of Pediatric Otorhinolaryngology

View full text Add to dashboard Cite

Section: Discussionmentioning

confidence: 99%

Papillary thyroid carcinoma in a 3-year-old child: Case report

Alkan

Seven

Sakalli

et al. 2008

International Journal of Pediatric Otorhinolaryngology

View full text Add to dashboard Cite

“…Advanced disease can be accompanied by hoarseness and sometimes labored breathing as a sign of recurrent laryngeal nerve or tracheal wall involvement, respectively. Other symptoms in young patients are rather occasional (25)(26)(27)(28)(29)(30)(31). Thyroid carcinomas in childhood do not cause hypo-or hyperthyroidism, the majority of patients are generally euthyroid.…”

Section: Clinical Course Of Childhood Patients With Thyroid Cancermentioning

confidence: 97%

Childhood thyroid cancer in Belarus, Russia, and Ukraine after Chernobyl and at present

Demidchik

Saenko

Yamashita

2007

Arq Bras Endocrinol Metab

118

View full text Add to dashboard Cite

Thyroid cancer in children is usually rare, but in the individuals exposed to radiation risk of disease increases considerably. After the Chernobyl accident in 1986, an over 10-fold maximal elevation in the incidence of thyroid cancer was registered about a decade later, cumulatively resulting in more than a thousand of newly diagnosed cases in children who lived in the territories of Belarus, Russia, and Ukraine affected by radioactive fallouts. Experience from the epidemic substantially promoted knowledge in clinical pediatric oncology, pathology and basic sciences. This article overviews epidemiology, clinical features, results of treatment and followup of childhood patients with radiation-induced Chernobyl thyroid cancer in comparison to sporadic cases diagnosed at present. In addition, we discuss general issues of pathology and molecular findings in childhood thyroid carcinomas. RESUMOCâncer de Tiróide na Infância na Bielorússia, Rússia, e na Ucrânia, Após Chernobil e Atualmente. O câncer de tiróide é habitualmente raro em crianças, mas em indivíduos expostos a radiação o risco da doença aumenta consideravelmente. Cerca de uma década após o acidente de Chernobil, em 1986, foi registrado um aumento de mais de 10 vezes na incidência de câncer de tiróide, resultando cumulativamente em mais de mil novos casos diagnosticados em crianças que viviam nos territórios da Bielorrússia, Russia, e Ucrânia, afetadas pela chuva radioativa. A experiência com essa epidemia resultou em conhecimento substancial de oncologia pediátrica clínica, patologia e ciências básicas. Este artigo analisa a epidemiologia, os achados clínicos, os resultados do tratamento e a evolução de pacientes pediátricos com câncer de tiróide induzido pela radiação de Chernobil, em comparação com casos esporádicos diagnosticados atualmente. Adicionalmente, serão discutidos tópicos de patologia e achados moleculares no carcinoma de tiróide infantil.

show abstract

“…Five of these had aggressive features, that is, a tumor larger than 4 cm, significant extrathyroid extension, and a metastatic node 3 cm or larger, and the remaining one was also graded N1. Previous studies from Western countries recommended routine total thyroidectomy with postoperative RAI therapy [36][37][38][39]. However, Hay et al showed that 73% of PTC patients younger than 21 years at the initial surgery, who died from nonthyroid malignancy during follow-up, underwent postoperative therapeutic irradiation, and they have issued warnings about routine RAI administration of the therapeutic dose [40].…”

Section: Distant Recurrence-free Survival (Drfs) Of 102 M0 Patientsmentioning

confidence: 99%