Surgery

Surgical Approach to Extensive Hidradenitis Suppurativa in the Perineal/Perianal and Gluteal Regions

“…In severe cases the treatment is limited at each operating session to an extent that enables mobilization and minimizes postoperative discomfort. Sometimes this method can be used in patients whose disease is so extensive that wide excision could not be contemplated [30]. Unroofing all the fistulous tracts and abscesses may be considered to create an extensive open wound consisting of multiple interconnecting bridges of skin, which can make healing easier and faster.…”

“…Conservative treatment methods have little or no effects on perineal/perianal hidradenitis suppurativa. Patients classified as Hurley stage III are almost always referred for wide excision and reconstructive surgery [30]. Therefore, surgical total excision must be considered even in the early stages of the disease to prevent further complications, such as abscesses, sinus tract formations, fistulisations, and scarring [2].…”

Multiple Freezing Points as a Test for Viability of Plant Stems in the Determination of Frost Hardiness

“…Techniques for determining viabilitv bv such criteria as regrowth (11,20). vital staining (10,19,23), fluorescence (8), electrolyte (3,26) or metabolite leakage (9,23), metabolic activity (14,23), plasmolysis-deplasmolysis (19,21) or macroscopic symptoms of damage (3,12,25), are frequently time-consuming and in some cases unreliable.…”

Epidermal psoriasiform hyperplasia, an unrecognized sign of folliculitis decalvans: A histological study of 26 patients

“…The similarity between HS and FD regarding the follicular hyperkeratosis and the interfollicular epidermal hyperplasia can be added to the 2 diseases’ other common characteristics. In the early stages, both diseases are characterized by a folliculitis whose perifollicular inflammatory infiltrate is composed of lymphocytes and neutrophils . Such neutrophils are most commonly situated on the upper part of the hair follicle in the case of FD.…”

“…Moreover, both diseases share a surprising and almost constant absence of inflammatory draining lymph nodes in spite of suppurating lesions which suggest that the immune system is involved in a common and specific manner. The fact that the hair follicle is the privileged place for inflammation in the form of folliculitis with neutrophils (superficial in FD, deep in HS) and that one of the only ways to stop it definitively is the destruction or removal of all hair follicles in the affected regions suggests that the hair follicle is the place to look for the cause of chronicity in both diseases. The presence of follicular hyperkeratosis in FD with a histological aspect of follicular plugging as described in both FD and HS raises the question of the role of follicular occlusion in its pathogenesis, like in HS, where it is currently considered as a crucial event …”