Surgery for Transcatheter Aortic Valve Replacement Endocarditis—A Single-Center Series

Rösch, Markus; Dohle, Daniel-Sebastian; Brendel, L.; Buschmann, K.; Beiras-Fernandez, A.; Vahl, C.-F.

doi:10.1055/s-0039-1678789

Cited by 1 publication

(7 citation statements)

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“…Prosthetic-valve endocarditis was diagnosed 17 ± 16 month after transcatheter aortic-valve replacement [ 1 ]. The following bacteria could be detected microbiologically: 6/10 patients’ blood cultures were positive for enterococcus faecalis, one of each for Staphylococcus epidermidis , Staphylococcus dysgalactiae and Streptococcus bovis [ 1 ]. One of the blood cultures remained negative.…”

Section: Methodsmentioning

confidence: 99%

“…One of the blood cultures remained negative. Indications for reoperation were large floating structures in 8/10 patients, sepsis with hypotension in 5/10, and severe aortic regurgitation in 3/10 patients [ 1 ]. The main clinical, echocardiographic, and microbiological findings and complications during infective endocarditis treatment of the cohort are shown in Table S2 .…”

Section: Methodsmentioning

confidence: 99%

“…Transcatheter aortic-valve replacement is increasingly being used for the treatment of aortic-valve stenosis [ 1 ]. Infective Endocarditis (IE) following transcatheter aortic-valve replacement is a rare but more frequently occurring complication with an incidence up to 3.4% [ 1 , 2 , 3 , 4 , 5 ]. In individual series, even higher incidence rates of 2.3–3.4% per patient-year have been reported [ 6 , 7 ].…”

Section: Introductionmentioning

confidence: 99%

“…But in many cases, surgical resection remains the only treatment option for prosthetic-valve endocarditis [ 1 ].…”

Section: Introductionmentioning

confidence: 99%

“…This study presents the short- and mid-term results of a small series of patients with infective endocarditis after previous transcatheter aortic-valve replacement treated via surgical TAVR explantation and surgical valve replacement [ 1 ].…”

Section: Introductionmentioning

confidence: 99%

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Surgery for Infective Endocarditis after Primary Transcatheter Aortic-Valve Replacement—A Retrospective Single-Center Analysis

Rösch

Brendel

Buschmann

et al. 2023

JCM

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Transcatheter aortic-valve replacement (TAVR) is increasingly being used for the treatment of aortic-valve stenosis. Therefore, the total number of patients with an aortic-valve prosthesis is increasing, causing the incidence of prosthetic-valve endocarditis to increase. Methods: Between March 2016 and July 2019, ten patients underwent surgery due to prosthetic-valve endocarditis after TAVR. They were identified in our institutional database and analyzed. Results: Infective endocarditis was diagnosed 17 ± 16 month after TAVR. Mean age was 79 ± 4.4 years. Microbiological detection showed 6/10 positive blood cultures for enterococcus faecalis. Median EuroScore II was 24.64%. The mean size of the surgically replaced aortic prosthesis was 23.6 ± 1.3 and that of the TAVR was 28.4 ± 2.3 mm. The surgically implanted aortic valves had a mean gradient of 8.5 ± 2.2 mmHg. One patient died in hospital due to septic multiorgan failure. After discharge, all patients survived with a mean follow-up of 9 ± 8 month. Conclusions: With a rising number of patients after TAVR, prosthetic-valve endocarditis will increasingly occur in patients who were previously considered high or intermediate risk. Our results show that patients with TAVR infective endocarditis can be operated on with good results. Surgical therapy should not be withheld from TAVR patients with infective endocarditis.

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Section: Methodsmentioning

confidence: 99%

Section: Methodsmentioning

confidence: 99%