Ergonomics in the operating room (OR), particularly for specialties that use loupes, is often overlooked. Although infrequently researched, it is essential for maximizing efficiency, endurance, and career longevity. The trauma of immobility in the OR can lead to frequent ergonomic injury. Surveys report approximately 80% of surgeons experience pain or strain, predominantly in the cervical or lumbar spine, during laparoscopic and open operations. 1,2 Ignoring these symptoms can hinder operative ability owing to chronic pain and lead to leaves of absence, cervical or lumbar spine surgery, or even early retirement. Appropriate posture, proper use of loupes, and exercise are 3 critical aspects of ergonomics and human factors that should be considered to help mitigate physical strain or pain, prevent injuries, and prolong career longevity.