Surgeon’s preference of subcutaneous tissue resection: most important factor for short-term complications in subcutaneous implant placement after mastectomy—results of a cohort study

Abstract

Purpose Little is known about the reason of high short-term complication rates after the subcutaneous placement of breast implants or expanders after mastectomy without biological matrices or synthetic meshes. This study aims to evaluate complications and their risk factors to develop guidelines for decreasing complication rates. Methods We included all cases of mastectomy followed by subcutaneous implant or expander placement between 06/2017 and 05/2018 (n = 92). Mean follow-up time was 12 months. Results Explantation occurred in 15 cases (16.3%). The surgeon's preference for moderate vs. radical subcutaneous tissue resection had a significant influence on explantation rates (p = 0.026), impaired wound healing or infection (requiring surgery) (p = 0.029, p = 0.003 respectively) and major complications (p = 0.018). Multivariate analysis revealed significant influence on complication rates for radical subcutaneous tissue resection (p up to 0.003), higher implant volume (p up to 0.023), higher drain volume during the last 24 h (p = 0.049), higher resection weight (p = 0.035) and incision type (p = 0.011). Conclusion Based on the significant risk factors we suggest the following guidelines to decrease complication rates: favoring thicker skin envelopes after surgical preparation, using smaller implants, removing drains based on a low output volume during the last 24 h and no use of periareolar incision with extension medial or lateral. We should consider ADMs for subcutaneous one-stage reconstructions. The individual surgeon's preference of subcutaneous tissue resection is of highest relevance for short-term complicationsthis has to be part of internal team discussions and should be considered in future trials for comparable results.

Risk factors and nursing countermeasures of postoperative pulmonary infection in patients with breast cancer

“…[8][9][10] Moreover, the resection range of radical mastectomy for breast cancer is large, which will damage the patient's appearance, cause anxiety, worry, and other negative emotions, and affect the prognosis of the patient. [11] There is an association between surgical infection and adverse cancer outcomes in breast cancer patients. [12] Therefore, the prevention and treatment of postoperative complications of breast cancer patients are of great significance to the prognosis of patients.…”

“…However, because radical mastectomy for breast cancer is traumatic and has severe tissue damage, it is easy to cause limited limb function and postoperative pain, which affects the quality of life of the patient [8–10] . Moreover, the resection range of radical mastectomy for breast cancer is large, which will damage the patient's appearance, cause anxiety, worry, and other negative emotions, and affect the prognosis of the patient [11] . There is an association between surgical infection and adverse cancer outcomes in breast cancer patients [12] .…”