Surfactants and fatty alcohol based novel nanovesicles for resveratrol: Process optimization, characterization and evaluation of functional properties in RAW 264.7 macrophage cells

Vankayala, Jaya Sravani; Battula, Surendra Nath; Kandasamy, Ruckmani; Antoniraj, M. Gover; Franklin, Magdaline Eljeeva Emerald; Pushpadass, Heartwin A.; Naik, Laxmana

doi:10.1016/j.molliq.2018.04.058

Cited by 32 publications

(25 citation statements)

References 42 publications

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“…In the direct sonication method the suspension composed by the membrane components and the aqueous phase is sonicated in an ice bath during several short cycles of high intensity, using a probe sonicator …”

Section: Preparation Methodsmentioning

confidence: 99%

“…Regarding vesicles, niosomes formed by Span 60 and cetyl alcohol presented very low or negligible toxicity against RAW264.7 macrophage cells (i. e. 92.5 % of cell viability at 40 μM) . Similarly, liposomes formed by soy phosphatidylcholine and OA indicated non‐cytotoxicity using 3T3 fibroblasts …”

Section: Overcoming Limitationsmentioning

confidence: 97%

“…96 % of RSV was released from its free form within 7 h, while the nanoencapsulated RSV was released ca. 81 % after 12 h (Figure ) …”

Section: Overcoming Limitationsmentioning

confidence: 99%

“…Additionally, Vankayala and co‐workers prepared biocompatible RSV‐loaded niosomes via sonication method using non‐ionic surfactants and a fatty alcohol as stabilizer . The formulation was prepared with Span 60 and cetyl alcohol in 1 : 0.5 molar ratio.…”

Section: Delivery Systemsmentioning

confidence: 99%

“…Regarding this intracellular scavenging activity, lipopolysaccharide‐stimulated macrophages showed a considerably reduction of fluorescence degree when RSV niosomes where used instead of free RSV. Thus, nanoencapsulation enhanced the functional property of RSV, possibly due to its higher degree of cell internalization …”

Section: Potential Applicationsmentioning

confidence: 99%

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Recent Strategies in Resveratrol Delivery Systems

2019

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Resveratrol, a natural polyphenolic stilbenoid widely found in grapes and wines, displays beneficial properties such as cardio‐protective, antioxidant and anti‐inflammatory activities. Trans‐resveratrol (RSV) is the most bioactive and more abundant stereoisomer found in nature. Despite the positive properties of RSV, there are various factors that limit its effectiveness, including low aqueous solubility, low oral bioavailability and chemical instability. During the last years, an increasing number of strategies such as nano and micro encapsulation have been developed in order to overcome these limitations and enhance the use of RSV in nutritional and pharmaceutical applications. This Review summarizes the advances and main properties of several RSV carriers and delivery systems reported during the last 5 years.

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Section: Preparation Methodsmentioning

confidence: 99%

Section: Overcoming Limitationsmentioning

confidence: 97%

“…96 % of RSV was released from its free form within 7 h, while the nanoencapsulated RSV was released ca. 81 % after 12 h (Figure ) …”

Section: Overcoming Limitationsmentioning

confidence: 99%

Section: Delivery Systemsmentioning

confidence: 99%

Section: Potential Applicationsmentioning

confidence: 99%

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Recent Strategies in Resveratrol Delivery Systems

2019

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Encapsulation Technologies Applied to Food Processing

Álvarez

Pando

2021

Food Formulation

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Optimization of Dynamic Interfacial Tension for Crude Oil–Brine System in the Presence of Nonionic Surfactants

Mohammadshahi

Shahverdi

Mohammadi

2019

J Surfact & Detergents

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In this study, interfacial tension (IFT) is measured between brine and crude oil (a sample of heavy oil from an Iranian oil reservoir) in the presence of two nonionic surfactants, KEPS 80 (Tween 80) and Behamid D, at different concentrations in order to optimize the concentrations of the surfactants. The surface response method is used to design the IFT measurement experiments. The experimental design and optimization is performed using the IFT as an objective function and temperature, concentration, and time as independent variables. In addition to the IFT measurement, various experiments such as stability tests of the surfactants in NaCl brine solutions, adsorption experiments on the carbonated rock surface, and phase behavior tests are performed to investigate the behavior of KEPS 80 and Behamid D in the enhanced oil recovery process. At the end, a model using the response surface statistical technique is designed for optimization of the concentrations of the surfactants, and a surfactant molecular migration mechanism is used for explanation of the dynamic IFT variation versus time. In the case of IFT experiments, the effect of surfactant concentration (at 1000, 3000, and 5000 ppm) on the dynamic IFT is investigated. The experiments are performed at four temperatures (25, 40, 50, and 67°C). The results show that the oil–brine IFT values can be reduced to about 4 mN m−1 in the presence of Behamid D and to about 1 mN m−1 in the presence of KEPS 80 at low concentrations.

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Surfactants and fatty alcohol based novel nanovesicles for resveratrol: Process optimization, characterization and evaluation of functional properties in RAW 264.7 macrophage cells

Cited by 32 publications

References 42 publications

Recent Strategies in Resveratrol Delivery Systems

Recent Strategies in Resveratrol Delivery Systems

Encapsulation Technologies Applied to Food Processing

Optimization of Dynamic Interfacial Tension for Crude Oil–Brine System in the Presence of Nonionic Surfactants

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