Surface Plasmon Resonance Enhanced Light Absorption and Photothermal Therapy in the Second Near-Infrared Window

Abstract

Enhanced near-field at noble metal nanoparticle surfaces due to localized surface plasmon resonance (LSPR) has been researched in fields ranging from biomedical to photoelectrical applications. However, it is rarely explored on nonmetallic nanomaterials discovered in recent years, which can also support LSPR by doping-induced free charge carriers, let alone the investigation of an intricate system involving both. Here we construct a dual plasmonic hybrid nanosystem Au-Cu9S5 with well controlled interfaces to study the coupling effect of LSPR originating from the collective electron and hole oscillations. Cu9S5 LSPR is enhanced by 50% in the presence of Au, and the simulation results confirm the coupling effect and the enhanced local field as well as the optical power absorption on Cu9S5 surface. This enhanced optical absorption cross section, high photothermal transduction efficiency (37%), large light penetration depth at 1064 nm, excellent X-ray attenuation ability, and low cytotoxicity enable Au-Cu9S5 hybrids for robust photothermal therapy in the second near-infrared (NIR) window with low nanomaterial dose and laser flux, making them potential theranostic nanomaterials with X-ray CT imaging capability. This study will benefit future design and optimization of photoabsorbers and photothermal nanoheaters utilizing surface plasmon resonance enhancement phenomena for a broad range of applications.

Galvanic Displacement Synthesis of Monodisperse Janus‐ and Satellite‐Like Plasmonic–Magnetic Ag–Fe@Fe3O4 Heterostructures with Reduced Cytotoxicity

“…The intimate contact between counterparts in the heterostructures should allow strong interactions and provide an efficient way for the modulation of the physical and chemical properties of the heterostructures 2. Among these properties, magnetic and optical properties can be efficiently controlled due to the synergistic effect and coupling effect 3. Especially, heterostructures consisted of noble metal and magnetic NPs, which could make good use of the special plasmonic resonance properties of noble metal counterpart and the unique magnetic properties of magnetic counterpart, have exhibited excellent potential applications in various fields such as multimodal imaging, targeting cancer therapy, and recyclable catalysis 4.…”

Pd-dispersed CuS hetero-nanoplates for selective hydrogenation of phenylacetylene

“…A variety of nanostructures, such as core-shell nanoparticles [5,6], heterodimers [7,8], metal-tipped nanorods [9,10], and metal island-decorated nanosheets [11], have been identified as excellent candidates for a wide range of applications. In particular, these materials are useful for photoelectric devices [12][13][14], photocatalysis [15][16][17], electrocatalysis [18][19][20], and theranostic [21] treatments. Recent investigations of metal-sulfide hybrid nanocrystals in organic catalysis have been explored creatively.…”

Unexpected high photothemal conversion efficiency of gold nanospheres upon grafting with two-photon luminescent ruthenium(II) complexes: A way towards cancer therapy?

“…5). The NIR SPR absorption of the AuNRs blue-shifted and decreased in intensity after laser exposure, indicating morphological changes to solid spheres due to the "melting effect" [51,52]. The latter was also confirmed by TEM images, showing large spherical Au particle formation after being exposed to laser irradiation.…”