Surface plasmon resonance based‐optical biosensor: Emerging diagnostic tool for early detection of diseases

Abstract

The development of diagnostic tools remains at the center of the health care system. In recent times optical biosensors have been widely applied in the scientific community, especially for monitoring protein–protein or nucleic acid hybridization interactions. Optical biosensors‐derived surface plasmon resonance (SPR) technology has appeared as a revolutionary technology at the current times. This review focuses on the research work in molecular biomarker evaluation using the technique based on SPR for translational clinical diagnosis. The review has covered both communicable and noncommunicable diseases by using different bio‐fluids of the patient's sample for diagnosis of the diseases. An increasing number of SPR approaches have been developed in healthcare research and fundamental biological studies. The utility of SPR in the area of biosensing basically lies in its noninvasive diagnostic and prognostic feature due to its label‐free high sensitivity and specificity properties. This makes SPR an invaluable tool with precise application in the recognition of different stages of the disease.

Editorial: Disease biomarker analysis based on optical biosensing

“…It also allows for non-invasive sample collection. With advancements in optical biosensing technology, many medical conditions including cancers, infectious diseases, and autoimmune disorders can be accurately diagnosed and efficiently treated (Singh et al, 2023;Tang et al, 2023). The combination of optical biosensing with emerging technologies such as material science, optics, and electronics has further accelerated its development in biomarker analysis (Qureshi et al, 2022).…”