2014
DOI: 10.1007/978-3-319-09834-0_4
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Surface Modifications of Nanodiamonds and Current Issues for Their Biomedical Applications

Abstract: Combining numerous unique assets, nanodiamonds are promising nanoparticles for biomedical applications. The present chapter focuses on the current knowledge of their properties. It shows how the control of their surface chemistry governs their colloidal behavior. This allows a fine tuning of their surface charge. Developments of bioapplications using nanodiamonds are summarized and further promising challenges for biomedicine are discussed.

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Cited by 34 publications
(13 citation statements)
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“…This paragraph focuses on recent reports dealing with hydrogenated or surface graphitized NDs. More details concerning previous studies were elsewhere provided [77]. Plasma hydrogenated NDs exhibit an excellent stability in aqueous solutions with a high positive Zeta potential [80].…”
Section: Specific Surface Properties Conferred By Surface Chemistrymentioning
confidence: 97%
“…This paragraph focuses on recent reports dealing with hydrogenated or surface graphitized NDs. More details concerning previous studies were elsewhere provided [77]. Plasma hydrogenated NDs exhibit an excellent stability in aqueous solutions with a high positive Zeta potential [80].…”
Section: Specific Surface Properties Conferred By Surface Chemistrymentioning
confidence: 97%
“…However, many approaches have been developed to enhance or incorporate fluorescence in ND, including doping, passivation, annealing in a vacuum, and so forth. Arnault (2019) has reviewed the recent surface modification techniques for ND and their potential biomedical applications in the respective fields.…”
Section: Applications In Biomedical Areasmentioning
confidence: 99%
“…The surface of ND has rich functional groups including contain ether-, hydroxyl-, carbonyl-, carboxyl-, amino-, and many other groups, as illustrated in Figure 1 (Arnault, 2015;Osswald, Yushin, Mochalin, Kucheyev, & Gogotsi, 2006). The surface of ND has rich functional groups including contain ether-, hydroxyl-, carbonyl-, carboxyl-, amino-, and many other groups, as illustrated in Figure 1 (Arnault, 2015;Osswald, Yushin, Mochalin, Kucheyev, & Gogotsi, 2006).…”
mentioning
confidence: 99%
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“…Glyconanodiamonds (GNDs) have been used towards this end. The surface of nanodiamonds (NDs) [31] 7 (ca. 5 nm in diameter) was functionalized by a Diels-Alder reaction with a ortho-quinodimethide generated in situ from 1,2-dibromomethylbenzene ( Figure 1b).…”
Section: Inhibitors Of Adherent-invasive and Uropathogenic E Colimentioning
confidence: 99%