Surface Modification Techniques for Biomedical Grade of Titanium Alloys: Oxidation, Carburization and Ion Implantation Processes

Izman, S.; Abdul-Kadir, Mohammed Rafiq; Anwar, Mahmood; Nazim, E. M.; Rosliza, R.; Shah, A.; Hassan, Mas Ayu

doi:10.5772/36318

Cited by 23 publications

(21 citation statements)

References 89 publications

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“…One solution is to use a 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-tetrazolium bromide (MTT) assay or to develop systems based on transparent material such as indium-tin oxide (ITO) and titanium dioxide (TiO 2 ) [10,11,12,13]. For instance, Titanium alloys are commonly employed to manufacture hard tissue replacement, including dental implants, bone plates and artificial hip joints [14,15,16,17,18]. These materials have positive characteristics such as good mechanical strength, lightweight, biocompatibility, and corrosion resistance, which generally depend of their surface properties [14,19].…”

Section: Introductionmentioning

confidence: 99%

Biocompatibility and Surface Properties of TiO2 Thin Films Deposited by DC Magnetron Sputtering

et al. 2014

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We present the study of the biocompatibility and surface properties of titanium dioxide (TiO2) thin films deposited by direct current magnetron sputtering. These films are deposited on a quartz substrate at room temperature and annealed with different temperatures (100, 300, 500, 800 and 1100 °C). The biocompatibility of the TiO2 thin films is analyzed using primary cultures of dorsal root ganglion (DRG) of Wistar rats, whose neurons are incubated on the TiO2 thin films and on a control substrate during 18 to 24 h. These neurons are activated by electrical stimuli and its ionic currents and action potential activity recorded. Through X-ray diffraction (XRD), the surface of TiO2 thin films showed a good quality, homogeneity and roughness. The XRD results showed the anatase to rutile phase transition in TiO2 thin films at temperatures between 500 and 1100 °C. This phase had a grain size from 15 to 38 nm, which allowed a suitable structural and crystal phase stability of the TiO2 thin films for low and high temperature. The biocompatibility experiments of these films indicated that they were appropriated for culture of living neurons which displayed normal electrical behavior.

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Section: Introductionmentioning

confidence: 99%

Biocompatibility and Surface Properties of TiO2 Thin Films Deposited by DC Magnetron Sputtering

et al. 2014

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“…Second, it helps empower their self-organization, and, third, it creates interest to offer compatibility with others (Viswanathan et al 2019). The clinical advantages achieved after surface modification are mentioned as good antimicrobial effect, high bioactivity, good cell growth and increased fatigue power (Izman et al 2012). The organic ligands such as polysaccharides, peptides, amino acids, proteins, etc.…”

Section: Introductionmentioning

confidence: 99%

Surface-Modified Noble Metal Nanoparticles as Antimicrobial Agents: Biochemical, Molecular and Therapeutic Perspectives

Das

Roy

Patra

et al. 2021

Environmental and Microbial Biotechnology

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Despite the progress of the development of antimicrobial therapeutics, the whole world is still under pressure of several microbial diseases. Antimicrobial drug development is therefore considered as one of the most practicable research works at present time. Even most of the pharmaceutical companies are investing to develop better therapeutic solutions against the life-threatening infectious diseases caused by Mycobacterium tuberculosis, Helicobacter pylori, Vibrio cholerae, Entamoeba histolytica, Plasmodium falciparum and many others. These microbial pathogens are not only a curse for human health but also a result in huge economic losses by affecting the health of economically important animals like poultry, cattle and other livestock. Considering the urgency, several effective antibiotics have been developed to combat microbial diseases and are available in the market. However, emergence of resistance against these drugs due to the maluses has created an alarming situation. In this scenario, the use of bioactive noble metal nanoparticles (silver, gold and platinum nanoparticles) has shown better therapeutic efficiency in terms of low treatment dose, less toxicity and absence of microbial resistance. Moreover, the use of several surface modifiers, coating and stabilizing agents resulted in enhancement of the bioactivity, rapid delivery and controlled drug release, improvement of biocompatibility and cytotoxicity. In this chapter, we have presented a comprehensive overview on the antimicrobial efficacy of noble metal nanoparticles along with the mechanistic insights behind their activity at the cellular and molecular level. Nabarun Chandra Das, Bishnupada Roy, and Ritwik Patra have been contributed equally to this chapter.

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“…Several methods of introducing interstitial atoms were successful in reducing wear on titanium alloys, such as ion implantation [17][18][19] or thermochemical treatments like nitriding and carburizing [20][21][22]. Also laser-induced chemical changes in Ti6Al4V can lead to significant improvements in its tribological behavior [23,24].…”

Section: Introductionmentioning

confidence: 99%

Influence of Interstitial Oxygen on the Tribology of Ti6Al4V

2020

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Titanium alloys are used for their good mechanical and corrosion properties, but generally experience poor wear behavior. This can effectively be counteracted by a thermal oxidation treatment, reducing wear significantly. Employing a special sample preparation, we study the transition of tribological properties between thermally oxidized and bulk Ti6Al4V on a single sample. While oxygen signal intensity and hardness followed an exponential decay from the surface to bulk material, tribological results showed a step-like transition from low to high friction and wear with increasing distance from the surface. Low wear was associated with minor abrasive marks, whereas high wear showed as severe adhesive material transfer onto the steel counter body. Besides the mechanical property of hardness, also a change in fracture behavior by interstitial oxygen could influence the observed tribological behavior.

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Surface Modification Techniques for Biomedical Grade of Titanium Alloys: Oxidation, Carburization and Ion Implantation Processes

Cited by 23 publications

References 89 publications

Biocompatibility and Surface Properties of TiO2 Thin Films Deposited by DC Magnetron Sputtering

Biocompatibility and Surface Properties of TiO2 Thin Films Deposited by DC Magnetron Sputtering

Surface-Modified Noble Metal Nanoparticles as Antimicrobial Agents: Biochemical, Molecular and Therapeutic Perspectives

Influence of Interstitial Oxygen on the Tribology of Ti6Al4V

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