Surface Modification of Nerve Guide Conduits with ECM Coatings and Investigating Their Impact on Schwann Cell Response
Luis Pinzon‐Herrera,
John Magness,
Hector Apodaca‐Reyes
et al.
Abstract:In this study, we investigated surface modification through the layer‐by‐layer method as a straightforward and highly stable approach for depositing layers of natural polymers onto a commercial nerve guide conduit (NGC), thereby mimicking the extracellular matrix. The application of NGCs for nerve regeneration is constrained by the size of the lesion, limiting their use to small gaps (1‐2 cm). The principal aim of this modification is to augment the cellular response specific to peripheral nerve injury (PNI) r… Show more
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