Surface Modification of Magnetic Iron Oxide Nanoparticles

Zhu, Nan; Ji, Haining; Yu, Peng; Niu, Jiaqi; Farooq, Muhammad Umar; Akram, Muhammad Waseem; Udego, I O; Li, Handong; Niu, Xiaobin

doi:10.3390/nano8100810

Cited by 401 publications

(273 citation statements)

References 219 publications

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“…There are three most common methods to generate silica shell on the surface of iron oxide NPs. By far, the most popular method is the Stöber process, in which the silica shell is formed in situ by the hydrolysis and condensation of a sol–gel precursor (e.g., tetraethoxysilane (TEOS) vinyltriethoxysilane (VTEOS), octadecyltrimethoxysilane) . Typically, the iron oxide NPs are first dispersed homogenously in the alcohol followed by the addition of silane (such as TEOS), and finally ammonia aqueous solution is dropped into the mixture solution and iron oxide@SiO 2 is formed.…”

Section: Hybrid Materialsmentioning

confidence: 99%

A Review on Iron Oxide‐Based Nanoarchitectures for Biomedical, Energy Storage, and Environmental Applications

et al. 2019

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Iron oxide nanoarchitectures with distinct morphologies from 1D to 3D have been developed using various wet chemical methods. They have been employed for a wide range of applications, including energy storage, biomedical, and environmental applications. The functional properties of iron oxide nanoarchitectures depend on the size, shape, composition, magnetic properties, and surface modification. To overcome the limitations of pure iron oxide nanostructures, hybridizations with various inorganic materials (e.g., silica, metals, metal oxides) and carbon‐based materials have been proposed. Herein, the recent advances in the preparation of various iron oxide nanoarchitectures are reviewed along with their functional applications in energy storage, biomedical, and environmental fields. Finally, the effects of various parameters on the functional performance of iron oxide nanostructures for these applications are summarized and the trends and future outlook on the development of iron oxide nanoarchitectures for these applications are also given.

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Section: Hybrid Materialsmentioning

confidence: 99%

A Review on Iron Oxide‐Based Nanoarchitectures for Biomedical, Energy Storage, and Environmental Applications

et al. 2019

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“…The co-precipitation method of iron salts is the simplest and most efficient chemical pathway to synthesis magnetic nanoparticle [10]. In this study, PEG-coated Fe 3 O 4 was synthesized following a simple two steps co-precipitation approach with various PEG concentrations.…”

Section: Introductionmentioning

confidence: 99%

A synthesis of polyethylene glycol (PEG)-coated magnetite Fe₃O₄ nanoparticles and their characteristics for enhancement of biosensor

Antarnusa

Suharyadi

2020

Mater. Res. Express

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The magnetite Fe 3 O 4 nanoparticles were synthesized by using chemical co-precipitation method and these nanoparticles were successfully coated by polyethylene glycol (PEG) with variation concentrations of PEG. The magnetite Fe 3 O 4 nanoparticles used as a bimolecular label (nano-tags), exhibiting a soft magnetic behavior with magnetization (M s ) of 77.16 emu g −1 and coercivity (H c ) of 50 Oe respectively. The polyethylene glycol (PEG) was used as a biocompatible polymer. The x-ray diffraction (XRD) patterns of the Fe 3 O 4 showed that Fe 3 O 4 was well crystallized. It also confirmed the existence of invers spinel. The diffraction peak of 35.4°was used to calculate the crystallite size. The estimation of Fe 3 O 4 average crystallite size is 12 nm, while the PEG-coated Fe 3 O 4 nanoparticles is 8.6 nm. The transmission electron microscopy (TEM) images of Fe 3 O 4 showed that the morphology of magnetite Fe 3 O 4 nanoparticle is spherical in shape with uniform grain size and good dispersibility despite the agglomeration it found in some place. The addition of PEG can decrease the agglomeration and reduce the particle size. The existence of PEG layer on Fe 3 O 4 was confirmed by Fourier transform infrared (FTIR) spectroscopy. The result of Vibrating Sample Magnetometer (VSM) showed that saturation magnetization (M s ) of Fe 3 O 4 nanoparticles decreased from 77.16 to 37.15 emu g −1 with the increase of PEG weight from 0% to 50%. Such Fe 3 O 4 nanoparticles with favorable size and tunable magnetic properties are promising biosensor applications.

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“…These single-domain iron oxide magnetic nanoparticles are present in three different phases, as magnetite, maghemite, and hematite (α-Fe 2 O 3 ) [15]. These nanoparticles generally demonstrate super-paramagnetic properties at ambient conditions even though their physical and chemical properties largely depend on the synthesis procedure and particle size [16]. According to the motions and interactions of the electrons available in the material, magnetism is divided in to five main classes as diamagnetism, paramagnetism, ferrimagnetism, ferromagnetism, and antiferromagnetism [17,18].…”

Section: Properties Of Magnetic Nanoparticlesmentioning

confidence: 99%

Magnetic and Quantum Dot Nanoparticles for Drug Delivery and Diagnostic Systems

Munasinghe¹,

Aththapaththu²,

Jayarathne³

2020

Colloid Science in Pharmaceutical Nanotechnology

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Nanoparticles are being used tremendously in biomedical sciences due to their promising chemical and physical properties. Magnetic nanoparticles and quantum dot nanocrystals are two of the main nanoparticle types used in the biomedical industry. The surface of these nanoparticles is further modified in order to obtain biocompatibility and surface functionalization. Magnetic properties, fluorescence, nanometer size, and availability of sites to modify its surface for bioconjugation provide greater potential to use these nanoparticles in targeted drug delivery technique and diagnostics. As a result, these nanoparticles create massive developments in the industrial operations. In this chapter, an overview of the nanoparticles used in drug delivery and diagnostic systems will be discussed. In addition, advantages in encapsulation of magnetic and quantum dot nanoparticles for bioconjugation and different methods of drug delivery will be addressed.

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Surface Modification of Magnetic Iron Oxide Nanoparticles

Cited by 401 publications

References 219 publications

A Review on Iron Oxide‐Based Nanoarchitectures for Biomedical, Energy Storage, and Environmental Applications

A Review on Iron Oxide‐Based Nanoarchitectures for Biomedical, Energy Storage, and Environmental Applications

A synthesis of polyethylene glycol (PEG)-coated magnetite Fe₃O₄ nanoparticles and their characteristics for enhancement of biosensor

Magnetic and Quantum Dot Nanoparticles for Drug Delivery and Diagnostic Systems

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Surface Modification of Magnetic Iron Oxide Nanoparticles

Cited by 401 publications

References 219 publications

A Review on Iron Oxide‐Based Nanoarchitectures for Biomedical, Energy Storage, and Environmental Applications

A Review on Iron Oxide‐Based Nanoarchitectures for Biomedical, Energy Storage, and Environmental Applications

A synthesis of polyethylene glycol (PEG)-coated magnetite Fe3O4 nanoparticles and their characteristics for enhancement of biosensor

Magnetic and Quantum Dot Nanoparticles for Drug Delivery and Diagnostic Systems

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Product

Resources

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A synthesis of polyethylene glycol (PEG)-coated magnetite Fe₃O₄ nanoparticles and their characteristics for enhancement of biosensor