Surface modification of magnesium alloy implants by nanostructured bredigite coating

Razavi, Mehdi; Fathi, Mohammadhossein; Savabi, Omid; Razavi, Seyed Mohammad Javad; Beni, Batoul Hashemi; Vashaee, Daryoosh; Tayebi, Lobat

doi:10.1016/j.matlet.2013.09.068

Cited by 50 publications

(24 citation statements)

References 20 publications

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“…11 The foremost drawback reported for magnesium alloys has been related to their high corrosion rate in the physiological environment. 12,13 For that reason, an initially low or ideally a controllable absorbable rate is wanted to avoid further deterioration of the adjacent tissue. 14,15 If the magnesium implants are being used to fix damage bone tissue, they are likely to lose their mechanical integrity earlier than tissue healing of bone due to their rapid corrosion and low bioactivity.…”

Section: Materials Science and Engineering: C Vol 48 (March 2015)mentioning

confidence: 99%

In vivo assessments of bioabsorbable AZ91 magnesium implants coated with nanostructured fluoridated hydroxyapatite by MAO/EPD technique for biomedical applications

Razavi

Fathi

Savabi

et al. 2015

Materials Science and Engineering: C

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Although magnesium (Mg) is a unique biodegradable metal which possesses mechanical property similar to that of the natural bone and can be an attractive material to be used as orthopedic implants, its quick corrosion rate restricts its actual clinical applications. To control its rapid degradation, we have modified the surface of magnesium implant using fluoridated hydroxyapatite (FHA: Ca10(PO4)6OH2 − xFx) through the combined micro-arc oxidation (MAO) and electrophoretic deposition (EPD) techniques, which was NOT THE PUBLISHED VERSION; this is the author's final, peer-reviewed manuscript. The published version may be accessed by following the link in the citation at the bottom of the page. 2015): pg. 21-27. DOI. This article is © Elsevier and permission has been granted for this version to appear in e-Publications@Marquette. Elsevier does not grant permission for this article to be further copied/distributed or hosted elsewhere without the express permission from Elsevier. Materials Science and Engineering: C, Vol 48 (March3 presented in our previous paper. In this article, the biocompatibility examinations were conducted on the coated AZ91 magnesium alloy by implanting it into the greater trochanter area of rabbits. The results of the in vivo animal test revealed a significant enhancement in the biocompatibility of FHA/MAO coated implant compared to the uncoated one. By applying the FHA/MAO coating on the AZ91 implant, the amount of weight loss and magnesium ion release in blood plasma decreased. According to the histological results, the formation of the new bone increased and the inflammation decreased around the implant. In addition, the implantation of the uncoated AZ91 alloy accompanied by the release of hydrogen gas around the implant; this release was suppressed by applying the coated implant. Our study exemplifies that the surface coating of magnesium implant using a bioactive ceramic such as fluoridated hydroxyapatite may improve the biocompatibility of the implant to make it suitable as a commercialized biomedical product.

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Section: Materials Science and Engineering: C Vol 48 (March 2015)mentioning

confidence: 99%

In vivo assessments of bioabsorbable AZ91 magnesium implants coated with nanostructured fluoridated hydroxyapatite by MAO/EPD technique for biomedical applications

Razavi

Fathi

Savabi

et al. 2015

Materials Science and Engineering: C

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“…It is well-known that surface modification can effectively enhance the properties of metals, especially for biomedical applications [17][18][19][20]. Coating of Mg alloys seems to be necessary to improve their degradation resistance [21,22].…”

Section: Introductionmentioning

confidence: 99%

Development and degradation behavior of magnesium scaffolds coated with polycaprolactone for bone tissue engineering

et al. 2014

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“…It offers excellent control of the thickness, stoichiometry, and microstructure of the deposited layers by suitably adjusting the applied voltage and treatment time. , and Razavi, Fathi, Savabi, Mohammad Razavi et al (2013 deposited nanostructured bredigite (Ca 7 MgSi 4 O 16 ), diopside (CaMgSi 2 O 6 ), and akermanite (Ca 2 MgSi 2 O 7 ) coatings by EPD over an MAO-coated AZ91 Mg alloy and showed that these coatings increased the resistance against corrosion and improved the in vitro bioactivity. EPD has been widely used for deposition of inorganic particles (particularly HA), bioactive glass, and their composites on stainless steel, titanium alloys, and shape memory alloys for biomedical applications.…”

Section: Electrophoretic Depositionmentioning

confidence: 99%

Surface modification of magnesium and its alloys for biomedical applications

Narayanan

Park

Lee

2015

Surface Modification of Magnesium and Its Alloys for Biomedical Applications

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Surface modification of magnesium alloy implants by nanostructured bredigite coating

Cited by 50 publications

References 20 publications

In vivo assessments of bioabsorbable AZ91 magnesium implants coated with nanostructured fluoridated hydroxyapatite by MAO/EPD technique for biomedical applications

In vivo assessments of bioabsorbable AZ91 magnesium implants coated with nanostructured fluoridated hydroxyapatite by MAO/EPD technique for biomedical applications

Development and degradation behavior of magnesium scaffolds coated with polycaprolactone for bone tissue engineering

Surface modification of magnesium and its alloys for biomedical applications

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