Surface Grafting of Electrospun Fibers: Multiscale Characterization and Perspective for Potential Applications

Berri, Nael; Elzein, Tamara; Dragoé, Diana; Houel-Renault, Ludivine; Barroca-Aubry, Nadine; Mouhamad, Abdel Wahab; Roger, Philippe

doi:10.1021/acsapm.2c00229

Cited by 2 publications

(2 citation statements)

References 35 publications

(48 reference statements)

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“…Similarly, 2D reconstruction ( Z ‐stack) images helped us to study grafted PIA surface homogeneity and surface‐bound distribution. Similar to our investigations, Berri et al 36 . performed surface grafting and demonstrated increased fluorescence intensity with an increase in grafting rate.…”

Section: Resultssupporting

confidence: 91%

“…Similarly, 2D reconstruction (Z-stack) images helped us to study grafted PIA surface homogeneity and surface-bound distribution. Similar to our investigations, Berri et al 36 performed surface grafting and demonstrated increased fluorescence intensity with an increase in grafting rate. Thus, the increase in sample homogeneity with increasing DOG correlates with the XPS results, where the O 1s /C 1s ratio increases with an increase in the DOG.…”

Section: Resultssupporting

confidence: 91%

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Functional surfaces by plasma grafting of itaconic acid onto polypropylene mesh: synthesis and structural investigations

Sethi,

Verma,

Mukhopadhyay

et al. 2023

Polymer International

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Polypropylene (PP) is an unflinching element of biomaterials for human healthcare, leading to enormous possibilities for their functional development within a broad range of biocompatible and bioreceptive materials. Plasma grafting of itaconic acid was carried out on a PP surface by oxygen plasma activation. The variation of grafting parameters, such as monomer concentration, reaction temperature and reaction time, as a function of the degree of grafting was investigated. The graft distribution and surface homogeneity of the PP surfaces were evaluated using confocal microscopy, field emission scanning electron microscopy and atomic force microscopy. These surface characterizations led to information about the impact of grafts on the material surface. © 2023 Society of Industrial Chemistry.

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Section: Resultssupporting

confidence: 91%

Section: Resultssupporting

confidence: 91%

Functional surfaces by plasma grafting of itaconic acid onto polypropylene mesh: synthesis and structural investigations

Sethi,

Verma,

Mukhopadhyay

et al. 2023

Polymer International

View full text Add to dashboard Cite

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Advances in Light-Responsive Smart Multifunctional Nanofibers: Implications for Targeted Drug Delivery and Cancer Therapy

Agiba,

Elsayyad,

ElShagea

et al. 2024

Pharmaceutics

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Over the last decade, scientists have shifted their focus to the development of smart carriers for the delivery of chemotherapeutics in order to overcome the problems associated with traditional chemotherapy, such as poor aqueous solubility and bioavailability, low selectivity and targeting specificity, off-target drug side effects, and damage to surrounding healthy tissues. Nanofiber-based drug delivery systems have recently emerged as a promising drug delivery system in cancer therapy owing to their unique structural and functional properties, including tunable interconnected porosity, a high surface-to-volume ratio associated with high entrapment efficiency and drug loading capacity, and high mass transport properties, which allow for controlled and targeted drug delivery. In addition, they are biocompatible, biodegradable, and capable of surface functionalization, allowing for target-specific delivery and drug release. One of the most common fiber production methods is electrospinning, even though the relatively two-dimensional (2D) tightly packed fiber structures and low production rates have limited its performance. Forcespinning is an alternative spinning technology that generates high-throughput, continuous polymeric nanofibers with 3D structures. Unlike electrospinning, forcespinning generates fibers by centrifugal forces rather than electrostatic forces, resulting in significantly higher fiber production. The functionalization of nanocarriers on nanofibers can result in smart nanofibers with anticancer capabilities that can be activated by external stimuli, such as light. This review addresses current trends and potential applications of light-responsive and dual-stimuli-responsive electro- and forcespun smart nanofibers in cancer therapy, with a particular emphasis on functionalizing nanofiber surfaces and developing nano-in-nanofiber emerging delivery systems for dual-controlled drug release and high-precision tumor targeting. In addition, the progress and prospective diagnostic and therapeutic applications of light-responsive and dual-stimuli-responsive smart nanofibers are discussed in the context of combination cancer therapy.

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Surface Grafting of Electrospun Fibers: Multiscale Characterization and Perspective for Potential Applications

Cited by 2 publications

References 35 publications

Functional surfaces by plasma grafting of itaconic acid onto polypropylene mesh: synthesis and structural investigations

Functional surfaces by plasma grafting of itaconic acid onto polypropylene mesh: synthesis and structural investigations

Advances in Light-Responsive Smart Multifunctional Nanofibers: Implications for Targeted Drug Delivery and Cancer Therapy

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