Surface Functionalization of Metallic Biomaterials: Present Trend and Future Perspectives

Rotella, Giovanna; Basile, Vito; Carlone, Pierpaolo; Col, Jessica Dal; Filice, Luigino; Orazi, Leonardo; Romoli, Luca; Rubino, Felice; Saffioti, Maria Rosaria

doi:10.1007/978-3-031-41163-2_15

Cited by 2 publications

(1 citation statement)

References 175 publications

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“…Some scholars also used hydroxyapatite for plasma spraying to obtain a coating, and found that the sprayed coating not only improves the contact between the bone and the implant, but also facilitates the fixation of the implant and to some extent prevents detachment [11]. In addition, chemical etching has also been proven to have the effect of improving the bonding strength of coatings [12]. Kono et al [13,14] functionalized titanium surfaces through chemical etching and found that this method can promote the adhesion and growth of coatings, thereby improving their biological activity.…”

Section: Introductionmentioning

confidence: 99%

Effect of SeO₂ on corrosion resistance of micro-arc oxidation

Zhang,

Zheng,

Chen

et al. 2023

Surface Engineering

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In order to make titanium alloy implants have better corrosion resistance in the human body, selenium-containing coating was added to the surface of Ti6Al7Nb through micro-arc oxidation. The results indicate that the coating has a higher thickness and lower roughness after the addition of selenium element. XRD, SEM, and XPS analysis showed that selenium element was successfully added into the coating. Then the dynamic polarization curve and EIS indicate that the prepared samples have better corrosion resistance in SBF solution compared to the unadded samples, (i corr ) and (E corr ) are 2.695 × 10 −8 A•cm −2 and 0.101 V, respectively. The addition of selenium helps to improve the biological corrosion resistance of the sample in body fluids.

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Section: Introductionmentioning

confidence: 99%

Effect of SeO₂ on corrosion resistance of micro-arc oxidation

Zhang,

Zheng,

Chen

et al. 2023

Surface Engineering

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Response of preosteoblasts on micromachined Ti-6Al-4V surface to microstructure dimension

Chen,

Yang,

Xie

et al. 2023

Biomed. Mater.

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The cell incubation depends on the cultured surface, but various machining methods produce different surface topographies, but it has not been clear how it is related to the topographic feature until now. Hence, the machined Ti-6Al-4V surface is characterized for preosteoblasts incubation via different mechanical fabrication. The relationship between surface topography created by various machining methods and cell incubation behaviour was explored. The objective is to control the surface preosteoblasts growth in machining of biological titanium alloy. According to the cell growth kinetic, the cell incubation behaviour was first proposed and modelled in relation to microstructural dimension and culture duration. Then, the topological cultured microstructure surface was fabricated via mechanical fabrication. Finally, the cell initial adhesion and incubation behaviour on microstructured surface was investigated. It is shown that the surface undulation on machined microstructure is conducive to controlling the direction and distribution of cell incubation from cell growth kinetic model. The cell culture can be controlled on the peak with a small undulation, while it is concentred on the sidewall with a high aspect ratio. Increasing the aspect ratio extends cell growth, while low aspect ratio promotes initial cell adhesion and growth rate. Within the optimal cultured duration, the microstructured surface is more favourable for cell survival, and the cell growth keep positive beyond critical aspect ratio. As a result, the cell adhesion ability is topologically controlled to 5.4 times higher and the growth rate can be improved by 101.7% on milled microgrooved surface. It may be applied to the rapid production of biomedical Ti-6Al-4V implant.

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Surface Functionalization of Metallic Biomaterials: Present Trend and Future Perspectives

Cited by 2 publications

References 175 publications

Effect of SeO₂ on corrosion resistance of micro-arc oxidation

Effect of SeO₂ on corrosion resistance of micro-arc oxidation

Response of preosteoblasts on micromachined Ti-6Al-4V surface to microstructure dimension

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Surface Functionalization of Metallic Biomaterials: Present Trend and Future Perspectives

Cited by 2 publications

References 175 publications

Effect of SeO2 on corrosion resistance of micro-arc oxidation

Effect of SeO2 on corrosion resistance of micro-arc oxidation

Response of preosteoblasts on micromachined Ti-6Al-4V surface to microstructure dimension

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Effect of SeO₂ on corrosion resistance of micro-arc oxidation

Effect of SeO₂ on corrosion resistance of micro-arc oxidation