Surface-enhanced resonance Raman spectroscopy of iron-dopamine complexes

Kowalchyk, Will K.; Davis, Kevin L.; Morris, Michael D.

doi:10.1016/0584-8539(94)00153-3

Cited by 22 publications

(9 citation statements)

References 22 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…9,000 min (150 h), with the solution having an intense violet color. This Fe-complex in solution is the same as that found by Kowalchyk [13] assigned to an Fe(III) bis(dopamine) anion complex, [Fe(III)(L 2-) 2 ] 1-, at pH 6-7. The complex prepared by Kowalchyk [13] presents a band at 570 nm and the strongest Raman band at 1,482 cm -1 (m 19a ) characteristic of the metal-catecholate complexes, and m C-O (1,272 cm -1 ), m 3 (1,330 cm -1 ), m 19a (1,425 cm -1 ), m 8a (1,566 cm -1 ).…”

Section: Resultsmentioning

confidence: 72%

“…This Fe-complex in solution is the same as that found by Kowalchyk [13] assigned to an Fe(III) bis(dopamine) anion complex, [Fe(III)(L 2-) 2 ] 1-, at pH 6-7. The complex prepared by Kowalchyk [13] presents a band at 570 nm and the strongest Raman band at 1,482 cm -1 (m 19a ) characteristic of the metal-catecholate complexes, and m C-O (1,272 cm -1 ), m 3 (1,330 cm -1 ), m 19a (1,425 cm -1 ), m 8a (1,566 cm -1 ). Our complex was studied using the resonance Raman spectroscopy showing the same bands observed by Kowalchyk, the characteristic dopacatecholate (L 2-) band at 1,482, 1,280, 1,338, 1,443, and 1,540 cm -1 [13,16].…”

Section: Resultsmentioning

confidence: 72%

“…The complex prepared by Kowalchyk [13] presents a band at 570 nm and the strongest Raman band at 1,482 cm -1 (m 19a ) characteristic of the metal-catecholate complexes, and m C-O (1,272 cm -1 ), m 3 (1,330 cm -1 ), m 19a (1,425 cm -1 ), m 8a (1,566 cm -1 ). Our complex was studied using the resonance Raman spectroscopy showing the same bands observed by Kowalchyk, the characteristic dopacatecholate (L 2-) band at 1,482, 1,280, 1,338, 1,443, and 1,540 cm -1 [13,16]. The formation of the Fe(III)-tri-catecholate complex, [Fe(III)(L 2-) 3 ] 3-was discounted because its absorption band occurs at 490 nm.…”

Section: Resultsmentioning

confidence: 99%

“…At pH 5 a complex of Fe(II) and catechol radicals (1:3) is dominant; at pH 8 a dimeric complex of Fe(III) (1:2 or 2:4) and above pH 12 a tri-catecholate of high spin Fe(III) (1:3). Kowalchyk [13] reported that the complex formed through the reaction between dopamine and FeCl 3 generates products of the catecholate type which are dependent on the pH. Between pH 6 and 7, the complex bi-catecholate, [Fe(Cat) 2 ] 1-predominated, characterized by the absorption band at ca.…”

Section: Introductionmentioning

confidence: 99%

See 3 more Smart Citations

A study of the aerobic reaction between dopamine and Fe(III) in the presence of S2O3 2−

Barreto

Silva

2009

Transition Met Chem

View full text Add to dashboard Cite

The reaction between Fe(III) and dopamine in aqueous solution in the presence of Na 2 S 2 O 3 was followed through UV-Vis spectroscopy, pH and oxyreduction potential (Eh) measurements. The formation and quick disappearing of the complex [Fe(III)HL 1-] 2? , HL 1-= monoprotonated dopamine was observed with or without S 2 O 3 2-at pH 3. An unexpected reaction occurs in presence of thiosulfate forming the stable anion complex [Fe(III)(L 2-) 2 ] 1-, L 2-= dopacatecholate (k = 580 nm) and the auto-increasing of the pH, from 3 to 7. It was proposed that H ? and molecular oxygen are consumed by free radical thiosulfate formed during the reaction.

show abstract

Section: Resultsmentioning

confidence: 72%

Section: Resultsmentioning

confidence: 72%

Section: Resultsmentioning

confidence: 99%

Section: Introductionmentioning

confidence: 99%

See 2 more Smart Citations

A study of the aerobic reaction between dopamine and Fe(III) in the presence of S2O3 2−

Barreto

Silva

2009

Transition Met Chem

View full text Add to dashboard Cite

show abstract

“…The molar absorptivity of Fe [III] DA 2 was determined to be 3,121 M −1 cm −1 which was within 7% of the previously published value (Sever and Wilker, 2004 ). As a result of the slightly acidic pH and DA concentration used in this study, the extent of formation of the tris -complex should be negligible (Kowalchyk et al, 1995 ; Sun et al, 2018a ). Even though the spectrum of DAC can overlap with that of the Fe [III] DA 2 complex at 580 nm, the influence of DAC was not considered given the low concentration present (nominally <1 μM) under all conditions investigated herein (Pezzella et al, 1997 ) and the small molar absorptivity of DAC at 580 nm (ε 580 = 439 M −1 cm −1 ).…”

Section: Methodsmentioning

confidence: 97%

Kinetic Modeling of pH-Dependent Oxidation of Dopamine by Iron and Its Relevance to Parkinson's Disease

et al. 2018

View full text Add to dashboard Cite

Parkinson's disease is the second most common neurodegenerative disease. While age is the most significant risk factor, the exact cause of this disease and the most effective approaches to mitigation remain unclear. It has long been proposed that dopamine may play a role in the pathology of Parkinson's disease in view of its ability to generate both protein-modifying quinones such as aminochrome and reactive oxygen species, especially in the presence of pathological iron accumulation in the primary site of neuron loss. Given the clinically measured acidosis of post-mortem Parkinson's disease brain tissue, the interaction between dopamine and iron was investigated over a pH range of 7.4 to 6.5 with emphasis on the accumulation of toxic quinones and generation of reactive oxygen species. Our results show that the presence of iron accelerates the formation of aminochrome with ferrous iron (Fe[II]) being more efficient in this regard than ferric iron (Fe[III]). Our results further suggest that a reduced aminochrome rearrangement rate coupled with an enhanced turnover rate of Fe[II] as a result of brain tissue acidosis could result in aminochrome accumulation within cells. Additionally, under these conditions, the enhanced redox cycling of iron in the presence of dopamine aggravates oxidative stress as a result of the production of damaging reactive species, including hydroxyl radicals.

show abstract

Surface-enhanced Raman spectroscopy of DOPA-containing peptides related to adhesive protein of marine mussel,Mytilus edulis

2000

View full text Add to dashboard Cite

The common blue marine mussel adheres to underwater surfaces using an adhesive protein (Mefp‐1) extruded from its foot. This highly hydroxylated protein contains a number of unusual amino acids, including 3,4‐dihydroxyphenylalanine (DOPA), which is thought to contribute to the crosslinking of the extruded threads and adhesion to the substratum. Mefp‐1 adheres to a wide variety of surfaces and is ultimately biodegradable. In this study we use surface‐enhanced Raman spectroscopy (SERS) to characterize the adsorption of DOPA‐containing peptides on colloidal gold. The peptides are simplified fragments of the Mefp‐1 consensus decapeptide repeat, Ala‐Lys‐Pro‐Ser‐Tyr‐DHP‐Hyp‐Thr‐DOPA‐Lys. Our results show that the peptides TΔKA, PTΔKA, and PPTΔKA (where Δ represents DOPA) coordinate to the gold surface through the catechol oxygens of the DOPA residue and through primary amine groups. The diproline sequence introduces conformational constraints that influence the conformations of the adsorbed peptides. These findings lay the groundwork for developing synthetic adhesives for underwater and medical applications. © 2000 John Wiley & Sons, Inc. Biopolymers (Biospectroscopy) 57: 92–102, 2000

show abstract

Surface-enhanced resonance Raman spectroscopy of iron-dopamine complexes

Cited by 22 publications

References 22 publications

A study of the aerobic reaction between dopamine and Fe(III) in the presence of S2O3 2−

A study of the aerobic reaction between dopamine and Fe(III) in the presence of S2O3 2−

Kinetic Modeling of pH-Dependent Oxidation of Dopamine by Iron and Its Relevance to Parkinson's Disease

Surface-enhanced Raman spectroscopy of DOPA-containing peptides related to adhesive protein of marine mussel,Mytilus edulis

Contact Info

Product

Resources

About