Surface enhanced Raman spectroscopy of phenolic antioxidants: A systematic evaluation of ferulic acid, p -coumaric acid, caffeic acid and sinapic acid

Aguilar-Hernández, Iris; Afseth, Nils Kristian; López–Luke, Tzarara; Contreras‐Torres, Flavio F.; Wold, Jens Petter; Ornelas‐Soto, Nancy

doi:10.1016/j.vibspec.2017.02.002

Cited by 99 publications

(57 citation statements)

References 75 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…The peak at 1605 cm −1 can be assigned to the stretching vibration of C=O, indicating that TCA, cinnamon bark biomolecules, and PI molecules interact with the AgNP surface mostly through their oxygen in their carbonyl group C=O [82,97]. This was also confirmed by UV-vis and FT-IR analysis above.…”

Section: Discussionsupporting

confidence: 53%

“…The peaks for C-OH stretching vibrations on the AgNP surface are available around 1019 cm −1 with different strength and sharpness in TCA-AgNP, TCA-AgNP-PI, Cinn-AgNP, and Cinn-AgNP-PI (Figure 7a-d) [78]. Bands with small intensity around 1340-1400 cm −1 and 1640 cm −1 reveal AgNP-carboxylate interactions (Figure 7a-d) [82,97]. Figure 7a reveals the characteristic ring-stretching peak at 1540 cm −1 verifying the satisfactory stabilizing effect of the TCA surrounding the AgNPs.…”

Section: Discussionmentioning

confidence: 99%

See 1 more Smart Citation

“Smart” Antimicrobial Nanocomplexes with Potential to Decrease Surgical Site Infections (SSI)

et al. 2020

View full text Add to dashboard Cite

The emergence of resistant pathogens is a burden on mankind and threatens the existence of our species. Natural and plant-derived antimicrobial agents need to be developed in the race against antibiotic resistance. Nanotechnology is a promising approach with a variety of products. Biosynthesized silver nanoparticles (AgNP) have good antimicrobial activity. We prepared AgNPs with trans-cinnamic acid (TCA) and povidone-iodine (PI) with increased antimicrobial activity. We synthesized also AgNPs with natural cinnamon bark extract (Cinn) in combination with PI and coated biodegradable Polyglycolic Acid (PGA) sutures with the new materials separately. These compounds (TCA-AgNP, TCA-AgNP-PI, Cinn-AgNP, and Cinn-AgNP-PI) and their dip-coated PGA sutures were tested against 10 reference strains of microorganisms and five antibiotics by zone inhibition with disc-and agar-well-diffusion methods. The new compounds TCA-AgNP-PI and Cinn-AgNP-PI are broad spectrum microbicidal agents and therefore potential coating materials for sutures to prevent Surgical Site Infections (SSI). TCA-AgNP-PI inhibits the studied pathogens stronger than Cinn-AgNP-PI in-vitro and on coated sutures. Dynamic light scattering (DLS), ultraviolet-visible spectroscopy (UV-Vis), Fourier Transform infrared spectroscopy (FT-IR), Raman, X-ray diffraction (XRD), microstructural analysis by scanning electron microscopy (SEM) and energy dispersive spectroscopy (EDS) confirmed the composition of TCA-AgNP-PI and Cinn-AgNP-PI. Smart solutions involving hybrid materials based on synergistic antimicrobial action have promising future perspectives to combat resistant microorganisms.Pharmaceutics 2020, 12, 361 2 of 36 20,000 related deaths in the United States in 2017 only and remains to be one of the important infection-associated mortality reasons [11,12]. The formation of biofilms on biotic and abiotic surfaces [13] paved the way for biofilm antibiotic tolerance as another major health threat [14,15]. This additional problem hampers the treatment of infections, most often gives rise to chronic infections, in the worst case to therapeutic failure, severe morbidity, and mortality [4]. More than 80% of microbial infections are caused by microbial biofilm formation and pose a severe health risk because treatment with antibiotics remains ineffective [16]. The incidence of chronic wound infections is increasing globally to alarming levels [17]. Chronic wounds are marked by high bacterial colonization and infection rates, which can be treated only by novel therapeutic approaches other than the use of conventional antibiotics [18,19]. Chronic wound tissues can contain microbiomes of complex communities with coexisting fungal and bacterial colonies of different strains within biofilms [20]. According to this inter-kingdom model, fungi like Candida albicans can offer structures for other bacteria (S. aureus, P. aeruginosa, Streptococcus spp., E. faecalis, E. coli, and Acinetobacter baumannii etc.) to attach, form intricate biofilms, and increase the resistance against any ...

show abstract

Section: Discussionsupporting

confidence: 53%

Section: Discussionmentioning

confidence: 99%

“Smart” Antimicrobial Nanocomplexes with Potential to Decrease Surgical Site Infections (SSI)

et al. 2020

View full text Add to dashboard Cite

show abstract

“…They are synthesized via the shikimate pathway where p-coumaric acid is converted into caffeic acid by hydroxylation, whereas the latter one forms ferulic acid upon methylation [50]. The antioxidant potential of these compounds depends primarily on the number of hydroxyl and methoxy groups attached to the phenyl ring [51]. Antioxidant capacities of a series of phenolic acids and flavonoids were earlier measured by Rice-Evans et al [44].…”

Section: Discussionmentioning

confidence: 99%

Antioxidants and Health-Beneficial Nutrients in Fruits of Eighteen Cucurbita Cultivars: Analysis of Diversity and Dietary Implications

et al. 2020

View full text Add to dashboard Cite

Aging is accompanied by gradual accumulation of molecular damage within cells in response to oxidative stress resulting from adverse environmental factors, inappropriate lifestyle, and numerous diseases. Adequate antioxidant intake is a key factor of proper diet. The study aimed to assess the antioxidant/antiradical capacities of Cucurbita fruits (18 cultivars of the species: C. maxima Duch., C. moschata Duch., C. pepo L., and C. ficifolia Bouché) grown in central Europe. The analyses were based on the FRAP (ferric reducing antioxidant power), CUPRAC (cupric ion reducing antioxidant capacity), and DPPH (2,2-diphenyl-1-picrylhydrazyl radical) assays. The content of phenolic compounds and β-carotene was evaluated with HPLC (high performance liquid chromatography), while the main macro- and micronutrients by ICP-OES (inductively coupled plasma mass spectrometry). The results revealed high intraspecies variability within the Cucurbita genus. The Japanese ‘Kogigu’ fruits were distinguished as extraordinary sources of phenolic compounds, including syringic and protocatechuic acids, catechin, and kaempferol. Another popular cultivar ‘Hokkaido’ exhibited the highest antioxidant and antiradical capacities. Most of the fruits proved to be rich sources of zinc and copper. The obtained data are discussed in the context of optimized nutrition of the elderly and suggest that Cucurbita fruits should become daily components of their diet.

show abstract

“…A lipid-removal procedure, as described in Experimental section, was thus necessarily prior to the sample into the detection [50,51]. The peak found at 1035 cm −1 presumably resulted from the surface of Al2O3 NPs/Ag HNS, which is likely the background thar contributed by the core shell structure of Ag HNS [52,53] and Al2O3 NPs upon Ag HNS, in the case of ampicillin in milk solution [44]. In Figure 6b, by taking these three peaks and low concentration (i.e., 0.01 ppm) of ampicillin in water and milk solution for a comparison, the results show the influence of ampicillin in different solutions.…”

Section: Nps/ag Hns For Trace Detection Of Ampicillin In Milk Solumentioning

confidence: 99%

Dielectric Nanoparticles Coated upon Silver Hollow Nanosphere as an Integrated Design to Reinforce SERS Detection of Trace Ampicillin in Milk Solution

et al. 2020

View full text Add to dashboard Cite

Surface-enhanced Raman scattering (SERS) technique is competent to trace detection of target species, down to the single molecule level. The detection sensitivity is presumably degraded by the presence of non-specific binding molecules that occupy a SERS-active site (or hot spot) on the substrate surface. In this study, a silver hollow nano-sphere (Ag HNS) with cavity has been particularly designed, followed by depositing dielectric nanoparticles (Di NPs) upon Ag HNS. In the integrated nanostructures, Di NPs/Ag HNS were furthermore confirmed by cutting through the cross sections using the Focused Ion Beam (FIB) technique, which provides the Scanning Electron Microscope (SEM) with Energy-dispersive Spectroscope (EDS) mode for identifying the distribution of Di NPs upon Ag HNS. The results have indicated that Di NPs/Ag HNS exhibits small diameter of cavity, and among Di NPs in this study, Al 2 O 3 with lower dielectric constant provides a much higher SERS enhancement factor (e.g.,~6.2 × 10 7 ). In this study, to detect trace amounts (e.g., 0.01 ppm) of Ampicillin in water or milk solution, Al 2 O 3 NPs/Ag HNS was found to be more efficient and less influenced by non-specific binding molecules in milk. A substrate with integrated plasmonic and dielectric components was designed to increase the adsorption of target species and to repulse non-specific binding molecules from SERS-active sites.Coatings 2020, 10, 390 2 of 15 techniques to provide rapid, food quality preserved, and bio-safety evaluation or analysis for related laboratories or industries [9][10][11].Surface-enhanced Raman scattering (SERS) technique delivers fingerprint information about a given substance using nearly roughened metal surfaces, metal nanoparticles (NPs), or metal nanostructures owing to their strong effect on the Raman-active peak(s) of target molecule. The enhancement of Raman-active modes is mainly due to the contribution of two effects through chemical mechanism (CM) and electromagnetic mechanism (EM) [12][13][14][15]. The CM depends on the adsorption of target molecules upon the "hot spots", which are generated at SERS-active sites; charge transfer occurs between the target molecule and the substrate, which may be enhanced by the polarizability of the molecule [16]. On the other hand, the EM relies on the physical attributes of the substrate as it is highly dependent on the composition, shape, and size of the metal substrate, which affect localized surface plasmon resonance (LSPR) in the metallic nanostructures. Therefore, available hot spots are formed in between the plasmonic nanostructures [15]. Aside from the mentioned factors, the intensity of SERS signals is also affected by the induced Raman laser wavelength, and thereafter, the interactions of target molecules toward the substrate [17,18].It has been widely accepted that the formation of Raman-active sites generates a highly enhanced EM field that leads to high enhancement factor (EF). The "hot spots" can be observed or even predicted using computer simulation and modeling to de...

show abstract

Surface enhanced Raman spectroscopy of phenolic antioxidants: A systematic evaluation of ferulic acid, p -coumaric acid, caffeic acid and sinapic acid

Cited by 99 publications

References 75 publications

“Smart” Antimicrobial Nanocomplexes with Potential to Decrease Surgical Site Infections (SSI)

“Smart” Antimicrobial Nanocomplexes with Potential to Decrease Surgical Site Infections (SSI)

Antioxidants and Health-Beneficial Nutrients in Fruits of Eighteen Cucurbita Cultivars: Analysis of Diversity and Dietary Implications

Dielectric Nanoparticles Coated upon Silver Hollow Nanosphere as an Integrated Design to Reinforce SERS Detection of Trace Ampicillin in Milk Solution

Contact Info

Product

Resources

About