Surface‐enhanced Raman spectroscopy for quantitative measurement of lactic acid at physiological concentration in human serum

Hsu, Po Hsiang; Chiang, Huihua Kenny

doi:10.1002/jrs.2609

Cited by 33 publications

(23 citation statements)

References 25 publications

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“…In addition to this, LA SERS spectrum shows strong Raman line at 1,390 and 823 cm −1 and weak lines at 528, 661, 745, 858, 928, 1,005, 1,040, 1,082, 1,138, 1,236, 1,454, 1,517, 1,601, 1,720, and 2,731 cm −1 . These spectral features are in good agreement with the earlier reports . The strong Raman line at 828 cm −1 is due to carbon and carboxylic group .…”

Section: Resultssupporting

confidence: 93%

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Detection and classification of volatile fatty acids using surface‐enhanced Raman scattering and density functional theory calculations

Chindaudon

Eiamchai

Horprathum

et al. 2019

J Raman Spectroscopy

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Volatile fatty acids of acetic, butyric, lactic, and propionic acids play an important role in the methane fermentation process. Particularly significant amount of propionic acid presence in the process will influence the methane fermentation efficiency. Herein, zigzag‐aligned silver nanorods were designed as surface‐enhanced Raman scattering (SERS)‐active substrates to establish the classification of volatile fatty acids against the traditional poor sensitive and time‐consuming titration and gas chromatography methods. SERS and chemometric method of principal component analysis is used for the detection and classification of volatile fatty acids. Density functional theory calculations were performed to understand the Raman vibrations and compare with experimental observations and to aid in the assignments of spectral lines. For the first time, the authors have used SERS technique to classify the acids. The findings suggest that this method is of great potential in the field of methane fermentation from industrial waste.

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Section: Resultssupporting

confidence: 93%

“…These spectral features are in good agreement with the earlier reports. [48,51] The strong Raman line at 828 cm −1 is due to carbon and carboxylic group. [50] The intense band at 1,390 cm −1 is from carboxylic group which shows that LA was adsorbed on SERS chips via carboxylic group.…”

Section: Dft Raman and Sers Spectra Of Lamentioning

confidence: 99%

Detection and classification of volatile fatty acids using surface‐enhanced Raman scattering and density functional theory calculations

Chindaudon

Eiamchai

Horprathum

et al. 2019

J Raman Spectroscopy

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“…The results presented in this paper will help to further improve the sensitivity of NWERS sensors. Along with other integrated photonics functionalities, these on-chip Raman sensors can be employed in many interesting application such as the detection of VOCs [28] in ambient air or sensing of bio-analytes in physiological concentration [29,30].…”

Section: Resultsmentioning

confidence: 99%

High index contrast photonic platforms for on-chip Raman spectroscopy

Raza¹,

Clemmen²,

Wuytens³

et al. 2019

Opt. Express

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Nanophotonic waveguide enhanced Raman spectroscopy (NWERS) is a sensing technique that uses a highly confined waveguide mode to excite and collect the Raman scattered signal from molecules in close vicinity of the waveguide. The most important parameters defining the figure of merit of an NWERS sensor include its ability to collect the Raman signal from an analyte i.e. "the Raman conversion efficiency" and the amount of "Raman background" generated from the guiding material. Here, we compare different photonic integrated circuit (PIC) platforms capable of on-chip Raman sensing in terms of the aforementioned parameters. Among the four photonic platforms under study, tantalum oxide and silicon nitride waveguides exhibit high signal collection efficiency and low Raman background. In contrast, the performance of titania and alumina waveguides suffers from a strong Raman background and a weak signal collection efficiency respectively.

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“…Hsu et al . applied silver colloidal NPs‐mediated SERS for rapid identification and quantification of lactic acid . They showed that their silver colloidal NPs‐mediated SERS technique was able to detect lactic acid at physiological concentrations in blood.…”

Section: Surface‐enhanced Raman Spectroscopymentioning

confidence: 99%