Surface-Enhanced Raman Spectroscopy-Based Approach for Ultrasensitive and Selective Detection of Hydrazine

Gu, Xin; Camden, Jon P.

doi:10.1021/acs.analchem.5b01566

Cited by 136 publications

(58 citation statements)

References 30 publications

Supporting

Mentioning

Contrasting

Order By: Relevance

“…22 These analytical methods typically require 4 sample preparation steps that are not amenable to intracellular detection. For in vivo analysis, fluorescent probes that enable sensitive and noninvasive detection of N 2 H 4 become absolutely necessary tools.…”

Section: Introductionmentioning

confidence: 99%

Naked-Eye and Near-Infrared Fluorescence Probe for Hydrazine and Its Applications in In Vitro and In Vivo Bioimaging

et al. 2015

View full text Add to dashboard Cite

Hydrazine has been applied diffusely in most of the chemical industry; however, it is a hazardous environmental pollutant and highly toxic to organisms. Selective, rapid, and sensitive detection of hydrazine thus becomes absolutely necessary in both biological and environmental sciences. Accordingly, fluorescence probes for hydrazine have been paid great attention in recent years. Disclosed here is the near-infrared (NIR) fluorescence probe with a turn-on fluorescent probe CyJ based on the structure-emission property relationships of the NIR dyes containing an acetyl group as the recognizing moiety. This new probe not only can be readily prepared, but also shows excellent sensing properties. First and most important of all, CyJ is highly selective for N2H4 over various anions, cations, and other amino compounds and has a low limit of detection (LOD) of hydrazine (5.4 ppb as fluorescence sensor and 6.1 ppb as UV sensor). Besides, CyJ exhibited a dramatic increase in fluorescence at λmax = 706 nm in the presence of N2H4, and it offers a rapid, colorimetric and vapor sensing detection process for N2H4 in both aqueous solution and diluted human serum. Furthermore, CyJ has good cell-membrane permeability and low cytotoxicity. In addition, we have successfully applied the CyJ to visualize N2H4 in live mouse and, for the first time, in tissues such as the liver, lung, kidney, heart, and spleen.

show abstract

Section: Introductionmentioning

confidence: 99%

Naked-Eye and Near-Infrared Fluorescence Probe for Hydrazine and Its Applications in In Vitro and In Vivo Bioimaging

et al. 2015

View full text Add to dashboard Cite

show abstract

“…8 Thus, the N2H4 content in water is strictly limited by almost all countries, such as it is restricted to ≤0.02 mg/L in drinking water by the Chinese government. 9 To date, there are several analytical methods for hydrazine detection, such as SERS, 10 electrochemical methods, 11,12 titration, 13 gas chromatography, 14 ultraviolet spectrometry, 15 and HPLC. 16 A simple and rapid method for hydrazine detection is still urgently needed.…”

Section: Introductionmentioning

confidence: 99%

A Natural Light Visible Colorimetric Responses Fluorescent Probe for Hydrazine Detection

Yang

et al. 2019

ANAL. SCI.

View full text Add to dashboard Cite

A natural light visible colorimetric responses fluorescent probe (Probe 1) was developed for N2H4 detection. The recognition mechanism of Probe 1 for hydrazine is based on addition-cyclization. The LOD of Probe 1 for N2H4 was 80.3 nM (0.0026 mg/L), which is below the national limited standard (0.02 mg/L). When various concentrations of N2H4 were added, the color of the Probe 1 solution was graded gradually from yellow to colorless, which could be observed under natural light. The changing course only takes 5 min. Furthermore, Probe 1 was successful applied to detect N2H4 in mineral water, seawater, tap water and river water. The obtained recovery ranged from 91.91-100.00%. Probe 1 has great potential, developed as a visual tool for N2H4 rapid detection.

show abstract

“…Some classic methods have been utilized for hydrazine detection. [6][7][8][9][10][11][12][13] However, these methods have disadvantages, such as complex operation and being time consuming. Comparatively, fluorescence spectroscopy has the advantages of high sensitivity and simple operation.…”

Section: Introductionmentioning

confidence: 99%

A New Fluorescent Turn-on Dual Interaction Position Probe for Determination of Hydrazine

Yin

et al. 2019

ANAL. SCI.

View full text Add to dashboard Cite

Reagents, materials and instrumentation Reagents were purchased from Shanghai Aladdin Biochemical Technology Co., Ltd. All reagents were AR. H2O was deionized water. NMR (600 MHz) spectra were obtained on Bruker AVANCE III. HRMS were carried out on Bruker, Apex Ultra 7.0T. UV-vis spectra were got at Agilent Cary 60. Fluorescence spectra were gained at Agilent Cary Eclipse. IR was obtained at Thermo Nicolet iS10. Synthesis of the probe Synthesis of compound 2. The synthetic routes of the probe and the control compounds are shown in Scheme 1. Dissolve compound 1 (450 mg), o-phthalic anhydride (296 mg) and

show abstract

Surface-Enhanced Raman Spectroscopy-Based Approach for Ultrasensitive and Selective Detection of Hydrazine

Cited by 136 publications

References 30 publications

Naked-Eye and Near-Infrared Fluorescence Probe for Hydrazine and Its Applications in In Vitro and In Vivo Bioimaging

Naked-Eye and Near-Infrared Fluorescence Probe for Hydrazine and Its Applications in In Vitro and In Vivo Bioimaging

A Natural Light Visible Colorimetric Responses Fluorescent Probe for Hydrazine Detection

A New Fluorescent Turn-on Dual Interaction Position Probe for Determination of Hydrazine

Contact Info

Product

Resources

About